The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
Solid lipid nanoparticles as drug delivery systems
Abstract
For a decade, trials have been made to utilize solid lipid nanoparticles (SLNs) as alternative drug delivery systems to colloidal drug delivery systems such as lipid emulsions, liposomes, and polymeric nanoparticles. Various lipid matrices, surfactants, and other excipients used in formulation, preparation methods, sterilization and lyophilization of SLNs are discussed in this article. Entrapment efficiency of drug carrier and its effect on physical parameters, drug release, and release mechanisms of various compositions are reviewed and discussed. Important points in characterization and stability of SLNs are outlined. Various in vitro studies carried out by different research groups are mentioned in addition to in vivo evaluation. Exploitation potential of SLNs to administer by various routes of administration are covered. Passive and active drug targeting using SLNs are presented.
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Cites
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Solid lipid nanoparticles (SLN) for controlled drug delivery â a review of the state of the art
Müller, R. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00087-4 · Cited by 3,759
Solid lipid nanoparticles Production, characterization and applications
Mehnert, W. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00105-3 · Cited by 3,150
Solid lipid nanoparticles (SLN) for controlled drug delivery – Drug release and release mechanism
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The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres
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Stealth Me. PEG‐PLA Nanoparticles Avoid Uptake by the Mononuclear Phagocytes System
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Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles
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Momin, M. Y., Gaddam, R. R., Kravitz, M., Gupta, A., & Vikram, A. (2021) · Cells · doi:10.3390/cells10113097 · Cited by 107
Metadata
- Authors
- Manjunath, K., Reddy, J. S., & Venkateswarlu, V.
- Venue
- Methods and Findings in Experimental and Clinical Pharmacology
- Publisher
- Portico
- Published
- 2005
- Volume
- 27
- Issue
- 2
- Pages
- 127
- ISSN
- 0379-0355 (ISSN-L)
- 2013-0155
- OpenAlex
- W1964896591
- Cited by
- 306
- References
- 80
- FWCI
- 3.70
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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