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Multiphoton plasmon-resonance microscopy
Open accessAbstract
A novel method for detection of noble-metal nanoparticles by their nonlinear optical properties is presented and applied for specific labeling of cellular organelles. When illuminated by laser light in resonance with their plasmon frequency these nanoparticles generate an enhanced multiphoton signal. This enhanced signal is measured to obtain a depth-resolved image in a laser scanning microscope setup. Plasmon-resonance images of both live and fixed cells, showing specific labeling of cellular organelles and membranes, either by two-photon autofluorescence or by third-harmonic generation, are presented.
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Cited by
Jain, P. K., Lee, K. S., El-Sayed, I. H., & El-Sayed, M. A. (2006) · The Journal of Physical Chemistry B · doi:10.1021/jp057170o · Cited by 4,603
Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
Huang, X., Neretina, S., & El‐Sayed, M. A. (2009) · Advanced Materials · doi:10.1002/adma.200802789 · Cited by 1,921
El-Sayed, I. H., Huang, X., & El-Sayed, M. A. (2005) · Nano Letters · doi:10.1021/nl050074e · Cited by 1,919
Au nanoparticles target cancer
Jain, P. K., El-Sayed, I. H., & El-Sayed, M. A. (2007) · Nano Today · doi:10.1016/s1748-0132(07)70016-6 · Cited by 1,157
Maiorano, G., Sabella, S., Sorce, B., Brunetti, V., Malvindi, M. A., Cingolani, R., & Pompa, P. P. (2010) · ACS Nano · doi:10.1021/nn101557e · Cited by 573
Metadata
- Authors
- Yelin, D., Oron, D., Thiberge, S., Moses, E., & Silberberg, Y.
- Venue
- Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2003-06-16
- Volume
- 11
- Issue
- 12
- Pages
- 1385
- ISSN
- 1094-4087 (ISSN-L)
- OpenAlex
- W2077887473
- Cited by
- 232
- References
- 0
- FWCI
- 4.01
- Type
- journal article
- Language
- en
- Open access
- gold
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