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High-speed optical frequency-domain imaging
Open accessAbstract
We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We derive and show experimentally that frequency-domain ranging provides a superior signal-to-noise ratio compared with conventional time-domain ranging as used in optical coherence tomography. A high sensitivity of -110 dB was obtained with a 6 mW source at an axial resolution of 13.5 microm and an A-line rate of 15.7 kHz, representing more than an order-of-magnitude improvement compared with previous OCT and interferometric imaging methods.
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Cited by
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Self-citationComprehensive volumetric optical microscopy in vivo
Yun, S. H., Tearney, G. J., Vakoc, B. J., Shishkov, M., Oh, W. Y., Desjardins, A. E., Suter, M. J., Chan, R. C., Evans, J. A., Jang, I.-K., et al. (2006) · Nature Medicine · doi:10.1038/nm1450 · Cited by 438
Self-citationApplication of optical coherence tomography in clinical diagnosis
Wang, Y., Liu, S., Lou, S., Zhang, W., Cai, H., & Chen, X. (2019) · Journal of X-Ray Science and Technology: Clinical Applications of Diagnosis and Therapeutics · doi:10.3233/xst-190559 · Cited by 42
Metadata
- Authors
- Yun, S., Tearney, G., de Boer, J., Iftimia, N., & Bouma, B.
- Venue
- Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2003-11-03
- Volume
- 11
- Issue
- 22
- Pages
- 2953
- ISSN
- 1094-4087 (ISSN-L)
- OpenAlex
- W2062714345
- Cited by
- 865
- References
- 0
- FWCI
- 22.03
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yun, S., Tearney, G., de Boer, J., Iftimia, N., & Bouma, B. (2003). High-speed optical frequency-domain imaging. Optics Express. https://doi.org/10.1364/oe.11.002953
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