The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cavity-enhanced optical frequency comb spectroscopy: application to human breath analysis
Open accessAbstract
Broad-bandwidth, high-spectral-resolution optical detection of human breath has identified multiple important biomarkers correlated with specific diseases and metabolic processes. This optical-frequency-comb-based breath analysis system comes with excellent performance in all criteria: high detection sensitivity, ability to identify and distinguish a large number of analytes, and simultaneous, real-time information processing. We demonstrate a minimum detectable absorption of 8 x 10(-10)cm(-1), a spectral resolution of 800 MHz, and 200 nm of spectral coverage from 1.5 to 1.7 microm where strong and unique molecular fingerprints exist for many biomarkers. We present a series of breath measurements including stable isotope ratios of CO(2), breath concentrations of CO, and the presence of trace concentrations of NH(3) in high concentrations of H(2)O.
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The HITRAN2016 molecular spectroscopic database
Gordon, I. E., Rothman, L. S., Hill, C., Kochanov, R. V., Tan, Y., Bernath, P. F., Birk, M., Boudon, V., Campargue, A., Chance, K. V., et al. (2017) · Journal of Quantitative Spectroscopy and Radiative Transfer · doi:10.1016/j.jqsrt.2017.06.038 · Cited by 7,721
Cited by
Picqué, N., & Hänsch, T. W. (2019) · Nature Photonics · doi:10.1038/s41566-018-0347-5 · Cited by 1,255
Fermann, M. E., & Hartl, I. (2013) · Nature Photonics · doi:10.1038/nphoton.2013.280 · Cited by 1,160
Ultralow-noise mode-locked fiber lasers and frequency combs: principles, status, and applications
Kim, J., & Song, Y. (2016) · Advances in Optics and Photonics · doi:10.1364/aop.8.000465 · Cited by 567
Phase-stabilized, 15 W frequency comb at 28–48 μm
Adler, F., Cossel, K. C., Thorpe, M. J., Hartl, I., Fermann, M. E., & Ye, J. (2009) · Optics Letters · doi:10.1364/ol.34.001330 · Cited by 314
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Metadata
- Authors
- Thorpe, M. J., Balslev-Clausen, D., Kirchner, M. S., & Ye, J.
- Venue
- Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2008
- Volume
- 16
- Issue
- 4
- Pages
- 2387
- ISSN
- 1094-4087 (ISSN-L)
- OpenAlex
- W2057837754
- Cited by
- 324
- References
- 1
- FWCI
- 9.24
- Type
- journal article
- Language
- en
- Open access
- gold
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- Thorpe, M. J., Balslev-Clausen, D., Kirchner, M. S., & Ye, J. (2008). Cavity-enhanced optical frequency comb spectroscopy: application to human breath analysis. Optics Express. https://doi.org/10.1364/oe.16.002387
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