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Cell damage in near-infrared multimode optical traps as a result of multiphoton absorption

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König, K., Liang, H., Berns, M. W., Tromberg, B. J.·1996·Optics Letters

Abstract

We report on cell damage of single cells confined in continuous-wave (cw), near-infrared (NIR) multimode optical traps as a result of multiphoton absorption phenomena. Trapping beams at NIR wavelengths less than 800 nm are capable of damaging cells through a two-photon absorption process. Cell damage is more pronounced in multimode cw traps compared with single-frequency true cw NIR traps because of transient power enhancement by longitudinal mode beating. Partial mode locking in tunable cw Ti:sapphire lasers used as trapping beam sources can produce unstable subnanosecond pulses at certain wavelengths that amplify multiphoton absorption effects significantly. We recommend the use of single-frequency long-wavelength NIR trapping beams for optical micromanipulation of vital cells.

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Metadata

Authors
König, K., Liang, H., Berns, M. W., & Tromberg, B. J.
Venue
Optics Letters
Published
1996-07-15
Volume
21
Issue
14
Pages
1090
ISSN
  • 0146-9592 (ISSN-L)
  • 1539-4794
OpenAlex
W2016952847
Cited by
158
References
0
FWCI
3.84
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Cell damage in near-infrared multimode optical traps as a result of multiphoton absorption. https://app.cochat.ai/papers/10.1364/ol.21.001090
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König, K., Liang, H., Berns, M. W., & Tromberg, B. J. (1996). Cell damage in near-infrared multimode optical traps as a result of multiphoton absorption. Optics Letters. https://doi.org/10.1364/ol.21.001090

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.