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Cited by 205

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Femtosecond laser disruption of subcellular organelles in a living cell

Open access
Watanabe, Wataru, Arakawa, Naomi, Matsunaga, Sachihiro, Higashi, Tsunehito, Fukui, Kiichi, Isobe, Keisuke, Itoh, Kazuyoshi·2004·Optics Express

Abstract

Subcellular organelles in living cells were inactivated by tightly focusing femtosecond laser pulses inside the cells. Photodisruption of a mitochondrion in living cells was experimentally confirmed by stacking three-dimensional confocal images and by restaining of organelles. The viability of the cells after femtosecond laser irradiation was ascertained by impermeability of propidium iodide as well as by the presence of cytoplasmic streaming.

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Metadata

Authors
Watanabe, W., Arakawa, N., Matsunaga, S., Higashi, T., Fukui, K., Isobe, K., & Itoh, K.
Venue
Optics Express
Published
2004
Volume
12
Issue
18
Pages
4203
ISSN
1094-4087 (ISSN-L)
OpenAlex
W2036725052
Cited by
205
References
0
FWCI
19.96
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Femtosecond laser disruption of subcellular organelles in a living cell. https://app.cochat.ai/papers/10.1364/opex.12.004203
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Watanabe, W., Arakawa, N., Matsunaga, S., Higashi, T., Fukui, K., Isobe, K., & Itoh, K. (2004). Femtosecond laser disruption of subcellular organelles in a living cell. Optics Express. https://doi.org/10.1364/opex.12.004203

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.