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High-resolution quantitative phase-contrast microscopy by digital holography
Open accessAbstract
Techniques of digital holography are improved in order to obtain high-resolution, high-fidelity images of quantitative phase-contrast microscopy. In particular, the angular spectrum method of calculating holographic optical field is seen to have significant advantages including tight control of spurious noise components. Holographic phase images are obtained with 0.5 mum diffraction-limited lateral resolution and largely immune from the coherent noise common in other holographic techniques. The phase profile is accurate to about 30 nm of optical thickness. Images of SKOV-3 ovarian cancer cells display intracellular and intranuclear organelles with clarity and quantitative accuracy.
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Cited by
Spectral-domain phase microscopy
Choma, M. A., Ellerbee, A. K., Yang, C., Creazzo, T. L., & Izatt, J. A. (2005) · Optics Letters · doi:10.1364/ol.30.001162 · Cited by 342
A Flexible Microdevice for Mechanical Cell Stimulation and Compression in Microfluidic Settings
Onal, S., Alkaisi, M. M., & Nock, V. (2021) · Frontiers in Physics · doi:10.3389/fphy.2021.654918 · Cited by 29
Pais, D. A. M., Galrão, P. R. S., Kryzhanska, A., Barbau, J., Isidro, I. A., & Alves, P. M. (2020) · Processes · doi:10.3390/pr8040487 · Cited by 25
Metadata
- Authors
- Mann, C. J., Yu, L., Lo, C.-M., & Kim, M. K.
- Venue
- Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2005
- Volume
- 13
- Issue
- 22
- Pages
- 8693
- ISSN
- 1094-4087 (ISSN-L)
- OpenAlex
- W2006161060
- Cited by
- 663
- References
- 0
- FWCI
- 11.07
- Type
- journal article
- Language
- en
- Open access
- gold
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- Mann, C. J., Yu, L., Lo, C.-M., & Kim, M. K. (2005). High-resolution quantitative phase-contrast microscopy by digital holography. Optics Express. https://doi.org/10.1364/opex.13.008693
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