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Cited by 14Quantum Information and CryptographyQuantum optics and atomic interactionsPhotorefractive and Nonlinear Optics

High-precision quantum transmittometry of DNA and methylene-blue using a frequency-entangled twin-photon beam in type-I SPDC

Open access
Motazedifard, Ali, Madani, Seyed Ahmad·2021·OSA Continuum
DOI 10.1364/osac.413830
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Abstract

Using the coincidence-count (CC) measurement of the generated frequency-entangled twin-photon beam (TWB) via the process of type-I spontaneous parametric-down conversion (SPDC) in BBO nonlinear crystal (NLC), we have precisely measured the transmittance of very diluted rabbit- and human-DNA, methylene-blue (MB) as a disinfectant, and a thin-film multilayer at near IR wavelength 810nm with an accuracy in order of %0.01 due to the quantum correlation, while the accuracy of classical-like measurement, single-count (SC), is in order of %0.1 in our setup. Moreover, using quantum measurement of the transmittance, the different types of DNA with the same concentration, and also very diluted (in order of pg/μ l) different concentrations of DNA and MB solutions, are distinguished and detected with high-reliability. Interestingly, in the case of human-DNA samples in contrast to our classical-like measurement, we could precisely detect and distinguish two very diluted concentrations 0.01ng/μl and 0.1ng/μl with high reliability while the commercial standard spectrometer device of our DNA-manufacturer could neither detect nor distinguish them. Surprisingly, measurement on the thin-film multilayer illustrates that the introduced method in this work might be performed to cancer/brain tissues or stem cells for cancer therapy and may hopefully open a pave and platform for non-invasive quantum diagnosis in the future.

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  • A type-II periodically poled PPKTP source has the potential to generate a type-II polarization-entangled Bell state.

    “This type of NLC has potential to generate the type-II polarization-entangled Bell-state (for more details about the state of SPDC, see Refs. [2], [12], [13]).”

    From Nonlocal realism tests and quantum state tomography in Sagnac-based type-II polarization-entanglement SPDC-source (2021) · cites this paper as [13]

    Section 2.3 (p. 4) says type-II SPDC generates photons with different polarizations, and Section 2.1 (p. 3) describes polarization-entangled Bell states and the wavepacket overlap needed to prepare them. The paper does not establish that a type-II PPKTP source can generate a Bell state; its experiment instead uses a type-I BBO crystal (Section 3.1, p. 7). (LLM, conf=0.84)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 17

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Cited by

Sorted by citations

Authors
Motazedifard, A., & Madani, S. A.
Affiliations
  • University of Isfahan (IR)
  • University of Tabriz (IR)
ORCID
Venue
OSA Continuum
Publisher
Optica Publishing Group
Published
2021-03-15
Volume
4
Issue
3
Pages
1049
ISSN
2578-7519 (ISSN-L)
DOI
10.1364/osac.413830
OpenAlex
W3134238124
Cited by
14
References
2
Citations by year
2026: 1 · 2025: 3 · 2024: 4 · 2022: 4 · 2021: 2
FWCI
0.88
Type
journal article
Language
en
Open access
Licence
Locations
  • OSA Continuum (publishedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • Figshare (submittedVersion, public-domain)
  • arXiv (Cornell University) (public-domain)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Quantum Information and Cryptography
  • Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Quantum optics and atomic interactions
  • Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Photorefractive and Nonlinear Optics
Keywords
DNA detection, methylene blue, multilayer films, near-infrared transmittance, quantum correlations, tumor imaging

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