HPLC Determination of Letrozole in Plasma Using Fluorescence Detection: Application to Pharmacokinetic Studies
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Solid-phase extraction methods with fluorescence detection for LTZ resulted in longer retention times and time-consuming processing.
“Fluorescence detection has been reported to quantify LTZ in human plasma and urine (Marfil et al. 1996; Zarghi et al. 2007). However, these solid-phase extraction methods resulted in longer retention times and time-consuming processing.”
From A simple, precise, and sensitive HPLC method for quantification of letrozole in rat plasma: development, validation, and preclinical pharmacokinetics (2021) · cites this paper as Zarghi et al. 2007
Cites
Letrozole: A Review of its Use in Postmenopausal Women with Advanced Breast Cancer
Lamb, H. M., & Adkins, J. C. (1998) · Drugs · doi:10.2165/00003495-199856060-00020 · Cited by 109 · see citing works
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in healthy postmenopausal women
Iveson, T. J. (1993) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.77.2.324 · Cited by 82 · see citing works
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Acharjya, S., Mallick, P., Panda, P., Kumar, K., & Annapurna, M. (2010) · Journal of Advanced Pharmaceutical Technology & Research · doi:10.4103/0110-5558.72425 · Cited by 46 · see citing works
“On a detailed literature survey, it was found that letrozole could be estimated by spectrophotometry,[3-4] Highperformance liquid chromatography (HPLC),[5-10] the microarray approach,[11] capillary gas chromatographic method with flame ionization detector,[12] and by gas chromatography – mass sprectrometry (GC / MS)[1…”
MethodHegde, A. R., Padya, B. S., Soman, S., & Mutalik, S. (2021) · Journal of Analytical Science and Technology · doi:10.1186/s40543-021-00276-4 · Cited by 17 · see citing works
“Fluorescence detection has been reported to quantify LTZ in human plasma and urine (Marfil et al. 1996; Zarghi et al. 2007).”
BackgroundLetrozole potentiometric PVC membrane and nano-composite carbon paste electrodes
Ganjali, M. R., Karimi, A., & Norouzi, P. (2012) · International Journal of Electrochemical Science · doi:10.1016/s1452-3981(23)13988-5 · Cited by 10 · see citing works
- Authors
- Zarghi, A., Foroutan, S. M., Shafaati, A., & Khoddam, A.
- Affiliations
- Shahid Beheshti University (IR)
- Corresponding author
- Zarghi, Afshin
- Venue
- Chromatographia
- Published
- 2007-08-29
- Volume
- 66
- Issue
- 9-10
- Pages
- 747-750
- ISSN
- 0009-5893 (ISSN-L)
- 1612-1112
- OpenAlex
- W1964317357
- Cited by
- 38
- References
- 2
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 4 · 2016: 2 · 2015: 1 · 2013: 1 · 2012: 5
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chromatographia (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Keywords
- letrozole, plasma drug quantification, therapeutic drug monitoring, pharmacokinetics, monolithic silica column, fluorescence detection, method validation, one-step extraction, aromatase inhibitors
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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