The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Validation of PHQ-2 and PHQ-9 to Screen for Major Depression in the Primary Care Population
Open accessAbstract
PURPOSE: Although screening for unipolar depression is controversial, it is potentially an efficient way to find undetected cases and improve diagnostic acumen. Using a reference standard, we aimed to validate the 2- and 9-question Patient Health Questionnaires (PHQ-2 and PHQ-9) in primary care settings. The PHQ-2 comprises the first 2 questions of the PHQ-9. METHODS: Consecutive adult patients attending Auckland family practices completed the PHQ-9, after which they completed the Composite International Diagnostic Interview (CIDI) depression reference standard. Sensitivities and specificities for PHQ-2 and PHQ-9 were analyzed. RESULTS: There were 2,642 patients who completed both the PHQ-9 and the CIDI. Sensitivity and specificity of the PHQ-2 for diagnosing major depression were 86% and 78%, respectively, with a score of 2 or higher and 61% and 92% with a score 3 or higher; for the PHQ-9, they were 74% and 91%, respectively, with a score of 10 or higher. For the PHQ-2 a score of 2 or higher detected more cases of depression than a score of 3 or higher. For the PHQ-9 a score of 10 or higher detected more cases of major depression than the PHQ determination of major depression originally described by Spitzer et al in 1999. CONCLUSIONS: We report the largest validation study of the PHQ-2 and PHQ-9, compared with a reference standard interview, undertaken in an exclusively primary care population. The PHQ-2 score or 2 or higher had good sensitivity but poor specificity in detecting major depression. Using a PHQ-2 threshold score of 2 or higher rather than 3 or higher resulted in more depressed patients being correctly identified. A PHQ-9 score of 10 or higher appears to detect more depressed patients than the originally described PHQ-9 scoring for major depression.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The PHQ-2 score was used to estimate the severity of depression, which assessed the frequency of depressed mood and anhedonia over the past two weeks [22].”
From Association between first-line antidepressant use and risk of dementia in older adults: a retrospective cohort study (2023) · cites this paper as [22]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The PHQ-8 has excellent internal consistency (Cronbach α=.89) and excellent test-retest reliability [47].”
From Feasibility and Preliminary Efficacy of Digital Interventions for Depressive Symptoms in Working Adults: Multiarm Randomized Controlled Trial (2023) · cites this paper as [47]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The PHQ-8 has excellent internal consistency (Cronbach α of .89 in primary care settings and .88 in this study at t0) and excellent test–retest reliability [49].”
From Feasibility and Preliminary Efficacy of Web-Based and Mobile Interventions for Common Mental Health Problems in Working Adults: Multi-Arm Randomized Pilot Trial (2022) · cites this paper as [49]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Spitzer, R. L. (1999) · JAMA · doi:10.1001/jama.282.18.1737 · Cited by 9,802
The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2003) · Medical Care · doi:10.1097/01.mlr.0000093487.78664.3c · Cited by 6,359
Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative.
Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., Lijmer, J. G., Moher, D., Rennie, D., de Vet, H. C. W., et al. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-1-200301070-00010 · Cited by 3,219
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., Lijmer, J. G., Moher, D., Rennie, D., & de Vet, H. C. W. (2003) · BMJ · doi:10.1136/bmj.326.7379.41 · Cited by 3,215
Users' Guides to the Medical Literature
Guyatt, G. H. (1993) · JAMA · doi:10.1001/jama.270.17.2096 · Cited by 3,083
Detecting and monitoring depression with a two-item questionnaire (PHQ-2)
Löwe, B., Kroenke, K., & Gräfe, K. (2005) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2004.09.006 · Cited by 1,473
Wittchen, H.-U., Lachner, G., Wunderlich, U., & Pfister, H. (1998) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050095 · Cited by 668
Spitzer, R. L., Williams, J. B. W., & Kroenke, K. (1999) · PsycTESTS Dataset · doi:10.1037/t02598-000 · Cited by 590
Screening for Depression: Recommendations and Rationale
U.S. Preventive Services Task Force* (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-10-200205210-00012 · Cited by 524
Li, C., Friedman, B., Conwell, Y., & Fiscella, K. A. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01103.x · Cited by 334
Flagged first, then by citations
Research works printed but not linked: 3
- N Z Med J. 2003;116(1171):U379.
- Ministry of Health. Taking the Pulse. The 1996/97 New Zealand Health Survey. Wellington: Ministry of Health; 1999:197-202.
- Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
Cited by
Sorted by citations
Items 401–500 of 1,000
Blood metabolic signatures of hikikomori, pathological social withdrawal
Setoyama, D., Matsushima, T., Hayakawa, K., Nakao, T., Kanba, S., Kang, D., & Kato, T. A. (2021) · Dialogues in Clinical Neuroscience · doi:10.1080/19585969.2022.2046978 · Cited by 22
“The severity of depression was assessed with the Patients Health Questionaire-9 (PHQ-9; Kroenke et al. 2001; Arroll et al. 2010), the Beck Depression Inventory-II (BDI-II) by self-rated questionnaires (Kojima et al.”
MethodBeck, A., Hamel, C., Thuku, M., Esmaeilisaraji, L., Bennett, A., Shaver, N., Skidmore, B., Colman, I., Grigoriadis, S., Nicholls, S. G., et al. (2022) · Systematic Reviews · doi:10.1186/s13643-022-02022-2 · Cited by 23
Naggie, S., Milstone, A. P., Castro, M., Collins, S. P., Lakshmi, S., Anderson, D. J., Cahuayme‐Zuniga, L., Turner, K. B., Cohen, L. W., Currier, J. S., et al. (2023) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2023.01.019 · Cited by 20
Paudel, K., Gupta, S., Gautam, K., Wickersham, J. A., Khati, A., Azwa, I., Ha, T., & Shrestha, R. (2023) · Journal of Community Health · doi:10.1007/s10900-023-01195-8 · Cited by 20
Dhaubhadel, S., Ganguly, K., Ribeiro, R. M., Cohn, J. D., Hyman, J. M., Hengartner, N., Kolade, B., Singley, A., Tanmoy Bhattacharya, A., Finley, P. D., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-51762-9 · Cited by 20
“…that are associated with our combined outcome, including demographics, vital signs, laboratory results, PHQ2 and PHQ9 mental health survey results 43 , opioid use, mental health diagnoses, serious health conditions, certain aspects of cardiovascular disease, and behavioral health treatments.”
Young, R. A., Benold, T., Whitham, J., & Burge, S. K. (2011) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2011.05.100298 · Cited by 20
“It is also likely that the depressive symptoms we identified with the PHQ-2 overestimated the prevalence of major depression, because it is a more sensitive than specific diagnostic tool.(47) Our study was also limited by using only one question to measure how CLBP interfered with work.”
Koball, A. M., Glodosky, N. C., Ramirez, L. D., Kallies, K. J., & Gearhardt, A. N. (2018) · Addiction Research & Theory · doi:10.1080/16066359.2018.1516757 · Cited by 20
Inverted U‐shaped relationship between vitamin D and ever‐reported eczema in US adults
Wei, J., Jaleel, T., MacLeod, A. S., & Ji, J. S. (2018) · Allergy · doi:10.1111/all.13708 · Cited by 20
“Depression indicator was ascertained through Patient Health Questionnaire (PHQ), a validated self‐reported assessment based on the nine symptoms for depression in the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM‐IV).(22) PHQ scores were classified as none (score 0‐4), mild (score 5‐9), moder…”
MethodSleep disturbances in orthopaedic trauma patients
Lu, K., Barron, J. O., Israel, H. A., & Cannada, L. K. (2019) · OTA International The Open Access Journal of Orthopaedic Trauma · doi:10.1097/oi9.0000000000000040 · Cited by 20
Padrnos, L. J., Scherber, R. M., Geyer, H. L., Langlais, B., Dueck, A. C., Kosiorek, H., Senyak, Z., Clark, M. M., Boxer, M. A., Cotter, M., et al. (2020) · Cancer Medicine · doi:10.1002/cam4.3380 · Cited by 19
Evaluation of eMentalHealth.ca, a Canadian Mental Health Website Portal: Mixed Methods Assessment
Jeong, D., Cheng, M., St-Jean, M., & Jalali, A. (2019) · JMIR Mental Health · doi:10.2196/13639 · Cited by 19
“She fills out a screening questionnaire for depression (which uses the validated PHQ-9 scale) [11], and it shows that she may have depression.”
Sutin, A. R., Luchetti, M., Stéphan, Y., & Terracciano, A. (2021) · Mental health and physical activity · doi:10.1016/j.mhpa.2021.100412 · Cited by 21
Chainé, S. M., Montoya, A. L., Maldonado, A. B., Aguirre, A. G. B., Robles, R., Rubio, C. R. G., Astudillo‐García, C. I., Chávez, I. A. L., & Gómez, M. G. R. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.656036 · Cited by 20
Attridge, M. D., & Dickens, S. P. (2022) · SAGE Open · doi:10.1177/21582440221087278 · Cited by 22
“The ultra-brief versions of the PHQ-9 for depression (Arroll et al., 2010; Kroenke & Spitzer, 2002) and the General Anxiety Disorder scale GAD-7 for anxiety (Spitzer et al, 2006) are combined as the Patient Health Questionnaire 4 or PHQ-4 (Kroenke et al., 2009; Löwe et al., 2010).”
BackgroundMethodQin, R., Yang, K., Abbasi, A., Dobolyi, D. G., Seyedi, S. S., Griner, E. L., Kwon, H., Cotes, R. O., Jiang, Z., Clifford, G. D., et al. (2024) · ACM Transactions on Management Information Systems · doi:10.1145/3673906 · Cited by 18
“Their use of LSTMs on all utterances as an unstructured conversation contradicted previous tendencies to filter to a key set of questions and use simple decision trees [6, 116], marking a shift to deep learning approaches.”
Health‐related quality of life in kidney transplant patients with diabetes
Dukes, J. L., Seelam, S., Lentine, K. L., Schnitzler, M. A., & Neri, L. (2013) · Clinical Transplantation · doi:10.1111/ctr.12198 · Cited by 19
“Even though the properties of depression screens seem promising, validation studies have shown these tools to have suboptimal accuracy and should be used along with a clinical evaluation to diagnose depression (43, 44).”
BackgroundGeraghty, A. W. A., Santer, M., Williams, S. J., McSharry, J., Little, P. S., Muñoz, R. F., Kendrick, T., & Moore, M. V. (2016) · Health An Interdisciplinary Journal for the Social Study of Health Illness and Medicine · doi:10.1177/1363459316674786 · Cited by 21
“Psychiatric models currently drawn on in primary care research (Kravitz et al., 2013; Kroenke et al., 2001; Mitchell et al., 2009) and recommended for practice (Arroll et al., 2010) often indicate disorder when the severity and duration of symptoms reach a predefined threshold and cause impairment.”
BackgroundPsychological Effect of a Mass Casualty Event on General Surgery Residents
Havron, W. S., Safcsak, K., Corsa, J., Loudon, A. M., & Cheatham, M. L. (2017) · Journal of surgical education · doi:10.1016/j.jsurg.2017.07.021 · Cited by 19
Lipschitz, J. M., Benzer, J. K., Miller, C. J., Easley, S. R., Leyson, J., Post, E. P., & Burgess, J. F. (2017) · BMC Health Services Research · doi:10.1186/s12913-017-2601-9 · Cited by 19
“Arroll B, Goodyear-Smith F, Crengle S, Gunn J, Kerse N, Fishman T, et al. Validation of PHQ-2 and PHQ-9 to screen for major depression in the primary care population.”
BackgroundInfluentialWhat type of happiness are you looking for? - A closer look at detecting mental health from language
Arseniev‐Koehler, A., Mozgai, S., & Scherer, S. J. (2018) · Workshop on Computational Linguistics and Clinical Psychology (CLPsych) · doi:10.18653/v1/w18-0601 · Cited by 22
“Rates for the sensitivity of the PHQ-8 are more like 77% in subsequent validation studies (Arroll et al., 2010; Gilbody et al., 2007).”
BackgroundNeupane, D., Levis, B., Bhandari, P. M., Thombs, B. D., & Benedetti, A. (2021) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1873 · Cited by 19
“cited the STARD reporting guideline (Arroll et al., 2010; Sherina et al., 2012).”
BackgroundAcheampong, K., Pan, X., Kaminga, A. C., & Liu, A. (2022) · Medicine · doi:10.1097/md.0000000000028862 · Cited by 19
“PHQ-9 score of 10or higher candetect more cases of major depression than the PHQ determination of major depression originally described by Spitzer et al in 1999.([20]) PHQ-9 has a good internal consistency (Cronbach’s alphas range from 0.”
BackgroundMichal, M., Prochaska, J. H., Ullmann, A., Keller, K., Göbel, S., Coldewey, M., Münzel, T. F., Wiltink, J., Beutel, M. E., & Wild, P. S. (2014) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12743 · Cited by 19
Validation of the Korean version of the thyroid cancer-specific quality of life questionnaire
Jeong, Y., Choi, J., Ahn, A.-L., Oh, E.-J., Oh, H.-K., Cho, D.-Y., Kweon, H.-J., & Park, K. S. (2015) · Annals of Surgical Treatment and Research · doi:10.4174/astr.2015.89.6.287 · Cited by 19
“Nine-item Patient Health Questionnaires The PHQ-9 is a nine-item questionnaire developed for depression screening in primary care settings, and each item has score ranging from 0 to 3 (leading to a maximum score of 27) [17].”
MethodDe Souza Marcovski, F. C., & Miller, L. J. (2023) · Current Psychology · doi:10.1007/s12144-021-02546-1 · Cited by 18
Beleigoli, A. M. R., Dafny, H. A., de Plaza, M. A. P., Hutchinson, C. L., Marin, T. S., Ramos, J. S., Suebkinorn, O., Gebremichael, L. G., Bulamu, N. B., Keech, W., et al. (2024) · Clinical Rehabilitation · doi:10.1177/02692155241236998 · Cited by 18
“…Health - CATCH database) captured dates of referrals, commence-ments, and completions; pre, post, 6-and 12-month cardiovascular risk factors, depression screening through Patient Health Questionnaire (PHQ)-2 and PHQ-9 16 ; self-reported smoking and medication adherence; and exercise capacity.”
BackgroundAwareness of Prediabetes and Diabetes among Persons with Clinical Depression
Rosedale, M. T., Strauss, S. M., Knight, C., & Malaspina, D. (2015) · International Journal of Endocrinology · doi:10.1155/2015/839152 · Cited by 18
“However, we note that this instrument was specifically developed for and is commonly used in primary care settings to screen for depression and is included in the DSM-5 as a recommended severity measure of clinical depression [27, 32, 53–55].”
MethodUsing a Single Screening Question for Depressive Symptoms in Patients With Acute Coronary Syndrome
Frazier, L. Q., Sanner, J. E., Yu, E., Cron, S. G., & Moeller, F. G. (2013) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0b013e318291ee16 · Cited by 18
“61 was reported using a PHQ-2 score of 3 or higher to determine depression, when compared with the Composite International Diagnostic Interview as a diagnostic standard.(23) The 1-question depressive symptom screening tool used in this study yielded similar probabilities, with a slightly lower specificity (82% vs 92%)…”
MethodResultInfluentialDrake, C., Meade, C., Hull, S. K., Price, A., & D, R. S. M. (2018) · Southern Medical Journal · doi:10.14423/smj.0000000000000892 · Cited by 18
A Prospective Longitudinal Study of Trajectories of Depressive Symptoms After Dysvascular Amputation
Roepke, A. M., Turner, A. P., Henderson, A. W., Goldberg, S. B., Norvell, D. C., Czerniecki, J. M., & Williams, R. M. (2018) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2018.11.024 · Cited by 18
Enabling Factors Associated with Receipt of Interconception Health Care
Gregory, E. F., Upadhya, K. K., Cheng, T. L., Psoter, K. J., & Mistry, K. B. (2019) · Maternal and Child Health Journal · doi:10.1007/s10995-019-02850-0 · Cited by 19
Poole, D. N., Liao, S. X., Larson, E., Hedt‐Gauthier, B., Raymond, N. A., Bärnighausen, T., & Fawzi, M. C. S. (2020) · Annals of General Psychiatry · doi:10.1186/s12991-020-0259-x · Cited by 19
Smith, J. D., Fu, E. S., Rado, J. T., Rosenthal, L. J., Carroll, A. J., Atlas, J. A., Carlo, A. D., Burnett‐Zeigler, I., Jordan, N., Brown, C. H., et al. (2021) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2021.100823 · Cited by 18
Zeng, C., Cao, W., Zhao, T., Li, L., & Hou, L. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03401-0 · Cited by 18
“The sensitivity and specificity for the diagnosis of depression with a PHQ-2 score of 2 or higher were 86 and 78%, respectively, and 61 and 92% with a score of 3 or higher [29].”
BackgroundFu, E. S., Carroll, A. J., Rosenthal, L. J., Rado, J. T., Burnett‐Zeigler, I., Jordan, N., Carlo, A. D., Ekwonu, A., Kust, A., Brown, C. H., et al. (2022) · Journal of General Internal Medicine · doi:10.1007/s11606-022-07750-8 · Cited by 18
“The PHQ-9 is a validated measure for depression screening and severity assessment in primary care settings.(34,35) PHQ-9 scores were pulled from the EDW for all participants.”
MethodLee, Y., Hyun, Y., You, M., Lee, H., Han, J.-O., & Seo, S. (2023) · BMC Public Health · doi:10.1186/s12889-023-15628-5 · Cited by 22
belayneh, W., Kassaye, Z., Tantu, T., Abera, N., Hantalo, A., Melkamu, B., & Gunta, M. (2023) · Frontiers in Reproductive Health · doi:10.3389/frph.2023.1244540 · Cited by 18
Choi, S., Hasche, L. K., & Nguyen, D. D. (2014) · Psychiatric Quarterly · doi:10.1007/s11126-014-9324-4 · Cited by 18
Cardarelli, R., Horsley, M., Ray, L., Maggard, N., Schilling, J., Weatherford, S., Feltner, F. J., & Gilliam, K. (2017) · Health Education Research · doi:10.1093/her/cyx064 · Cited by 18
Toorabally, N., Mercer, C. H., Mitchell, K. R., Blell, M. T., Burns, F. M., Gilson, R. J. C., McGregor-Read, J., Allan, S., de Ruiter, A., Dhairyawan, R., et al. (2019) · AIDS Care · doi:10.1080/09540121.2019.1653436 · Cited by 18
“We identified a number of confounding variables a priori from the literature including age, ethnicity, number of reported chronic medical conditions, and depression (screened using the Patient Health Questionnaire-2 or PHQ-2 (Arroll et al., 2010; Arroll, Khin, & Kerse, 2003)).”
MethodAddiction Medicine Practice-Based Research Network (AMNet): Assessment Tools and Quality Measures
Clarke, D. E., Ibrahim, A., Doty, B., Patel, S., Gibson, D., Pagano, A., Thompson, L. R., Goldstein, A. B., Vocci, F. J., & Schwartz, R. P. (2021) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s305972 · Cited by 18
Garg, R., McQueen, A., Roberts, C., Butler, T., Grimes, L. M., Thompson, T., Caburnay, C. A., Wolff, J. M., Javed, I., Carpenter, K., et al. (2021) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2021.100857 · Cited by 18
“The mean stress score in the sample is well above population norms [51], and the mean depression score easily surpasses the threshold at which further depression screening is recommended [52].”
BackgroundQuality of life and frailty outcomes following surgical and transcatheter aortic valve replacement
Surman, T. L., Abrahams, J. M., Kim, J.-W., Surman, H. E., Roberts-Thomson, R., Montarello, J. K., Edwards, J., Worthington, M. G., & Beltrame, J. F. (2022) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-022-01876-w · Cited by 18
Weitzman, E. R., Wisk, L. E., Minegishi, M., Cox, R., Lunstead, J., Brogna, M., & Levy, S. (2022) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2021.10.017 · Cited by 18
“Depressive symptoms were assessed via the Patient Health Questionnaire-2 [24]; anxiety was screened via the Generalized Anxiety Disorder scale [25].”
MethodMartino, S. C., Elliott, M. N., Haviland, A. M., Saliba, D., Burkhart, Q., & Kanouse, D. E. (2015) · Health Services Research · doi:10.1111/1475-6773.12359 · Cited by 18
“9) for detecting major depression in general primary care samples (Kroenke, Spitzer, and Williams 2003; Arroll et al. 2010) and samples of older patients (Li et al.”
BackgroundInfluentialLino, V. T. S., Portela, M. C., Camacho, L. A. B., Atie, S., de Lima, M. J. B., Rodrigues, N. C. P., Barros, M. B. D. L., & Andrade, M. K. D. N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113778 · Cited by 18
“The PHQ-2 score cutoffs identified in our study differed from cutoffs reported by others in studies of the elderly [30] and of individuals with low educational levels [31], including in PC settings [11].”
BackgroundResultAdams, D. J., Remick, R. A., Davis, J. C., Vazirian, S., & Khan, K. (2015) · BMJ Open Sport & Exercise Medicine · doi:10.1136/bmjsem-2015-000036 · Cited by 18
“The PHQ-9 is a multipurpose instrument for screening, diagnosing, monitoring and measuring the severity of depression.(33) 34 3.”
MethodChoi, S., Kim, G., & Lee, S. (2016) · Psychiatric Quarterly · doi:10.1007/s11126-016-9418-2 · Cited by 18
“The PHQ-2 consists of two items that can be used as a quick screener for depression in the primary care setting [30].”
MethodCan Patients Forecast Their Postoperative Disability and Pain?
Alokozai, A., Eppler, S. L., Lu, L. Y., Sheikholeslami, N., & Kamal, R. N. (2019) · Clinical Orthopaedics and Related Research · doi:10.1097/corr.0000000000000627 · Cited by 18
“The PHQ-2 is a validated short screening test for unipolar depression and includes two items probing the frequency of depressed mood and anhedonia [3].”
Tønnesen, H., & Noguer, C. B. I. (2010) · Hispana · Cited by 18
Taylor, R. W., Male, R., Economides, M., Bolton, H., & Cavanagh, K. (2023) · JMIR Formative Research · doi:10.2196/41590 · Cited by 15
“The PHQ-8 has excellent internal consistency (Cronbach α =.89) and excellent test-retest reliability [47].”
Spangenberg, L., Brähler, E., & Glaesmer, H. (2012) · Zeitschrift für Psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2012.58.1.3 · Cited by 29
AlHamad, N. S., & Alamri, K. (2021) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_697_21 · Cited by 18
“In this regard, there is a compelling need for further investigation among our respondents who had a PHQ-9 score of >10 to correctly identify any major depression and institute the necessary early intervention.[30] The negative affective experience scores, particularly depression, unhappiness, and anger, ranked highes…”
BackgroundKim, A. B., Cheng, B. T., & Hassan, S. (2022) · JAAD International · doi:10.1016/j.jdin.2022.05.011 · Cited by 17
Sulaiman, S. K., Tsiga-Ahmed, F. I., Arora, T., Faris, M. E., Musa, M. S., Kareem, Y. A., Dayyab, F. M., Hussein, A., Sale, S., Javaid, S. F., et al. (2023) · Brain and Behavior · doi:10.1002/brb3.2990 · Cited by 20
Diabetes distress in a Medicaid sample: The role of psychosocial and health-related factors
Verdecias, N., McQueen, A., Nordheim, D. V., Broussard, D. J., Smith, R. E., & Kreuter, M. W. (2023) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2023.108495 · Cited by 16
Emotional eating behaviors in later life: Identifying key factors for healthy aging
Hawash, M. M., Alhazmi, A. H., El‐Sayed, M. M., Mushfiq, S., El‐Ashry, A. M., Ahmed, H. A., Abd-Elrahman, S. I., Kamel, W. W., & Hafez, S. A. (2023) · Geriatric Nursing · doi:10.1016/j.gerinurse.2023.11.012 · Cited by 20
Hirsch, O., Donner‐Banzhoff, N., & Bachmann, V. (2013) · Journal of Transcultural Nursing · doi:10.1177/1043659613482003 · Cited by 17
“81 (convergent validity), sensitivity values were around 92%, and specificity around 78% (Arroll et al., 2010; Gilbody, Richards, Brealey, & Hewitt, 2007; Kroenke, Spitzer, Williams, & Lowe, 2010).”
BackgroundDeSantis, B., Jackson, M. J., Duncan, B. L., & Reese, R. J. (2016) · Primary Health Care Research & Development · doi:10.1017/s1463423616000311 · Cited by 17
“Both the PHQ-2 and PHQ-9 have demonstrated high sensitivity and specificity for detecting major depression in primary care (Arroll et al., 2010) and a two-step approach to primary care depression screening is often utilized to improve diagnostic accuracy and assess severity.”
MethodJones, H. A., Eddy, L. D., Rabinovitch, A. E., Snipes, D. J., Wilson, S. A., Parks, A. M., Karjane, N. W., & Svikis, D. S. (2017) · Journal of Clinical Psychology · doi:10.1002/jclp.22538 · Cited by 18
“The PHQ-2 is an excellent screen for depression in a primary care setting (Arroll et al., 2010) and has strong psychometric properties (Kroenke et al.”
BackgroundEhde, D. M., Alschuler, K. N., Sullivan, M. D., Molton, I. R., Ciol, M. A., Bombardier, C. H., Curran, M. C., Gertz, K. J., Wundes, A., & Fann, J. R. (2017) · Contemporary Clinical Trials · doi:10.1016/j.cct.2017.10.001 · Cited by 17
An Autoethnographic Examination of Postpartum Depression
Frankhouser, T., & Defenbaugh, N. L. (2017) · The Annals of Family Medicine · doi:10.1370/afm.2107 · Cited by 19
Schnall, A. H., Roth, J., Ellis, B. R., Seger, K. R., Davis, M., & Ellis, E. M. (2019) · Disaster Medicine and Public Health Preparedness · doi:10.1017/dmp.2019.6 · Cited by 17
“1 likelihood ratio of generalized anxiety disorder.(8,9) These show a slight, but insignificant, decrease as compared to November 2017.”
ResultBalawi, M. M. A., Faraj, F., Anazi, B. D. A., & Balawi, D. M. A. (2019) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2019.789 · Cited by 19
“The following Table describes the provisional diagnoses for scoring classes [37] (Table 1).”
BackgroundCondiciones de salud mental durante la pandemia por COVID-19
Chainé, S. M., Montoya, A. L., Maldonado, A. B., Aguirre, A. G. B., Robles, R., Rosales, F. L., & Fernández-Cáceres, C. (2020) · Revista Internacional de Investigación en Adicciones · doi:10.28931/riiad.2020.2.03 · Cited by 21
McNaughton, H., Weatherall, M., McPherson, K. M., Fu, V. W. Y., Taylor, W. J., McRae, A., Thomson, T., Gommans, J., Green, G., Harwood, M. L. N., et al. (2021) · Clinical Rehabilitation · doi:10.1177/0269215521993648 · Cited by 19
Kaufmann, C., Zehetmair, C., Jahn, R., Marungu, R., Cranz, A., Kindermann, D., Friederich, H., Bozorgmehr, K., & Nikendei, C. (2021) · Health & Social Care in the Community · doi:10.1111/hsc.13508 · Cited by 17
Elsman, E. B. M., van Munster, E. P. J., van Nassau, F., Verstraten, P., van Nispen, R. M. A., & van der Aa, H. P. A. (2022) · Translational Vision Science & Technology · doi:10.1167/tvst.11.1.16 · Cited by 17
Omérov, P., Steineck, G., Nyberg, T., Runeson, B., & Nyberg, U. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003108 · Cited by 19
Amutah‐Onukagha, N., Doamekpor, L. A., & Gardner, M. (2016) · Journal of Racial and Ethnic Health Disparities · doi:10.1007/s40615-016-0312-2 · Cited by 20
“A PHQ-9 score higher than 10 places a person into the moderate depression, moderately severe depression, or severe depression categories [29].”
Food Insecurity and Substance use in People with HIV Infection and Substance use Disorder
Raja, A., Heeren, T., Walley, A. Y., Winter, M. R., Mešić, A., & Saitz, R. (2020) · Substance Abuse · doi:10.1080/08897077.2020.1748164 · Cited by 16
“The score was dichotomized as below three or three and higher.(54) This dichotomization has been used in many other studies with PLWH.”
MethodEngaging Diverse Older Adults With Cognitive Impairment and Caregivers in Advance Care Planning
Kotwal, A., Barnes, D. E., Volow, A. M., Li, B. H., Boscardin, W. J., & Sudore, R. L. (2021) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000465 · Cited by 16
Patient Activation Measure in Dialysis-Dependent Patients in the United States
Cukor, D., Zelnick, L. R., Charytan, D. M., Shallcross, A. J., & Mehrotra, R. (2021) · Journal of the American Society of Nephrology · doi:10.1681/asn.2021030315 · Cited by 16
Beleigoli, A. M. R., Nicholls, S. J., Brown, A. D. H., Chew, D. P., Beltrame, J. F., Maeder, A. J., Maher, C. A., Versace, V. L., Hendriks, J., Tideman, P. A., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-054558 · Cited by 16
Rist, T. M., Segars, K. A., & Oyer, S. L. (2022) · Facial Plastic Surgery & Aesthetic Medicine · doi:10.1089/fpsam.2022.0037 · Cited by 16
Depressive symptoms and conspiracy beliefs
Green, J., Druckman, J. N., Baum, M., Lazer, D. M. J., Ognyanova, K., & Perlis, R. H. (2022) · Applied Cognitive Psychology · doi:10.1002/acp.4011 · Cited by 17
“We measured participants’ experiences with depression via the Patient Health Questionnaire (PHQ-9), a widely used tool to screen patients for depression in primary care settings (Kroenke and Spitzer 2002, Arroll et al. 2010).”
MethodMengin, A. C., Nourry, N., Séverac, F., Berna, F. S., Bemmouna, D., Costache, M. E., Fritsch, A., Frey, I., Ligier, F., Engel, N., et al. (2024) · Internet Interventions · doi:10.1016/j.invent.2024.100736 · Cited by 16
“The Patient Health Questionnaire - 2 items version (PHQ-2) (Arroll et al., 2010) was used to screen for depression (Cronbach ’ s α = 0.73).”
MethodInfluentialKorthuis, P. T., Hoffman, K. A., Wilson‐Poe, A. R., Luoma, J. B., Bazinet, A. D., Pertl, K., Morgan, D. L., Cook, R., Bielavitz, S., Myers, R., et al. (2024) · Journal of Psychopharmacology · doi:10.1177/02698811241257839 · Cited by 16
“Service systems and providers will have to choose from available indicators, such as the Patient Health Questionnair (PHQ-9) (Arroll et al., 2010), and balance response burden with validity.”
Are andropause symptoms related to depression?
Khosravi, S., Ardebili, H. E., Larijani, B. A., Nedjat, S., Nasrabadi, A. N., Ardebili, M. E., Dabiran, S., & Samizadeh, E. (2015) · Aging Clinical and Experimental Research · doi:10.1007/s40520-015-0341-4 · Cited by 16
“The latter is used as a screening and assessment tool for depression [20].”
BackgroundMethodYang, J. X., Stevenson, M. J., Valsdottir, L. R., Ho, K. K. L., Spertus, J. A., Yeh, R. W., & Strom, J. B. (2019) · Heart · doi:10.1136/heartjnl-2019-315835 · Cited by 18
Leightley, D., Rona, R. J., Shearer, J., Williamson, C., Gunasinghe, C., Simms, A., Fear, N. T., Goodwin, L., & Murphy, D. (2020) · JMIR Research Protocols · doi:10.2196/19720 · Cited by 16
“I/C I/C I/C I/C I/C I/C I/C Depression (PHQ2d) [53]”
Oral health and academic performance or absenteeism: Findings from a University in Southern Brazil
Karam, S. A., Costa, F. D. S., Schwendicke, F., Corrêa, M. B., & Demarco, F. F. (2020) · Community Dentistry And Oral Epidemiology · doi:10.1111/cdoe.12598 · Cited by 17
Síndrome de Burnout y dependencia al alcohol en estudiantes de Medicina
González, I., Alfonzo, A., Aranda, J., Cameron, S., Chávez, D., Duré, N., Pino, A., Sawatzky, D. P., Rojas, S. J. O., Villalba, S., et al. (2020) · Medicina Clínica y Social · doi:10.52379/mcs.v4i2.147 · Cited by 16
Public perceptions and disparities in access to telehealth orthopaedic services in the COVID-19 era
Puzzitiello, R. N., Moverman, M. A., Pagani, N. R., Ryan, S. P., Salzler, M. J., Jawa, A., & Menendez, M. E. (2021) · Journal of the National Medical Association · doi:10.1016/j.jnma.2021.02.007 · Cited by 16
Beehr, T. A., Ragsdale, J. M., & Kochert, J. F. (2014) · Journal of Organizational Behavior · doi:10.1002/job.1974 · Cited by 17
Implications of two-stage depression screening for identifying persons with thoughts of self-harm
Pratt, L. A., & Brody, D. J. (2013) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2013.09.007 · Cited by 16
“We examine the cut point of three and a lower cut point of two, as has been done in other studies [27–30].”
ResultArrabales, R. (2020) · doi:10.31234/osf.io/nfas4 · Cited by 26
“Nowadays, depression misdiagnose and undertreatment in primary care is still a concern [10], and primary care physicians are encouraged to use screening tools, such as Patient Health Questionaire-2 (PHQ-2) [11], Patient Health Questionaire-9 (PHQ-9) [12] and Beck Depression Inventory (BDI) [13], so that appropriate tr…”
Weems, J. A., Rhodes, S., & Powers, J. S. (2021) · Geriatrics · doi:10.3390/geriatrics6030080 · Cited by 15
“Burden and depression scores were self-assessed at each of the first and last class sessions using the 4-item Zarit Burden Interview Scale [7] and the PHQ-2 depression questionnaire [8].”
MethodFuchs, C. H., Haradhvala, N., Evans, D. R., Nash, J. M., Weisberg, R. B., & Uebelacker, L. A. (2016) · Families, Systems, & Health · doi:10.1037/fsh0000237 · Cited by 15
Erez, C., & Gordon, I. (2024) · Assessment · doi:10.1177/10731911241261168 · Cited by 17
“The Patient Health Questionnaire-2 (PHQ-2).”
Lebrett, M. B., Crosbie, E. J., Yorke, J., Hewitt, K., Rowlands, A., Badrick, E., Evans, D. G., Balata, H., Booton, R., & Crosbie, P. A. J. (2022) · Lung Cancer · doi:10.1016/j.lungcan.2022.04.003 · Cited by 15
Osman, D. M., Ahmed, G. K., Farghal, M. M., & Ibrahim, A. K. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04239-w · Cited by 16
Bryan, C. J., Allen, M. H., Bryan, A. O., Thomsen, C. J., Baker, J. C., & May, A. M. (2023) · The Joint Commission Journal on Quality and Patient Safety · doi:10.1016/j.jcjq.2023.08.008 · Cited by 15
Carvajal, D. N., Ghazarian, S. R., Crowne, S. S., Brown, P. B., Carter‐Pokras, O., DUGGAN, A. K., & Barnet, B. (2014) · Women s Health Issues · doi:10.1016/j.whi.2013.10.003 · Cited by 15
“Depressive symptoms were measured using the Patient Health Questionnaire (PHQ-9), a nine-item instrument predictive of depression (Arroll et al., 2010; Kroenke, Spitzer, & Williams, 2001; Richardson et al., 2010) and validated among both English and Spanish speaking Latinas (Merz, Malcarne, Roesch, Riley, & Sadler, 20…”
MethodInfluentialAssociation between anxious symptoms and sleeping medication use among US older adults
Harris, D. A., McNicoll, L., Epstein-Lubow, G. P., & Thomas, K. S. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4795 · Cited by 15
“The PHQ‐2 is a 2‐question standardized and validated measure of depression in both clinical and elderly populations.(28,29) PHQ‐2 questions are “Over the last month, how often have you: a) had little interest or pleasure in doing things; b) felt down, depressed, or hopeless.”
MethodWei, J., Zhang, J. J., & Ji, J. S. (2018) · Archives of Environmental & Occupational Health · doi:10.1080/19338244.2018.1467874 · Cited by 15
“ment based on the nine DSM-IV symptoms for depression.(37,39) PHQ scores were classified as none (score 0–4), mild (score 5–9), moderate (score 10–14), and severe”
MethodCreatinine synthesis rate and muscle strength and self-reported physical health in dialysis patients
Poppe, E. S. J. M., Polinder‐Bos, H. A., Huberts, M., Vogels, S., Ipema, K. J. R., Gansevoort, R. T., Westerhuis, R., Bakker, S. J. L., Gaillard, S., & Franssen, C. F. M. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.07.010 · Cited by 15
MacLean, S. E., Corsi, D. J., Litchfield, S., Kucharski, J., Genise, K., Selaman, Z., Testa, V., & Hatcher, S. (2019) · Journal of Medical Internet Research · doi:10.2196/15001 · Cited by 15
“The PHQ-9 is often used as a screening tool for major depressive disorder in primary care practice [28].”
BackgroundMethodSelf-citationJin, H., & Wu, S. (2020) · Journal of Medical Internet Research · doi:10.2196/17282 · Cited by 15
“Previous studies have tested the validity of conducting standardized depression screening, such as the Patient Health Questionnaire (PHQ), by using paper-based self-reported assessment [18-20], in-person interviewer (INTW) assessment [21,22], and telephone INTW assessment [11,21].”
BackgroundKrist, A. H., O'Loughlin, K. M., Woolf, S. H., Sabo, R., Hinesley, J., Kuzel, A. J., Rybarczyk, B. D., Kashiri, P. L., Brooks, E. M., Glasgow, R. E., et al. (2020) · Trials · doi:10.1186/s13063-020-04463-3 · Cited by 14
Metadata
- Authors
- Arroll, B., Goodyear-Smith, F., Crengle, S., Gunn, J., Kerse, N., Fishman, T., Falloon, K., & Hatcher, S.
- Affiliations
- University of Auckland (NZ)
- Venue
- The Annals of Family Medicine
- Publisher
- Annals of Family Medicine
- Published
- 2010-07-01
- Volume
- 8
- Issue
- 4
- Pages
- 348-353
- ISSN
- 1544-1709 (ISSN-L)
- 1544-1717
- PMC
- PMC2906530
- OpenAlex
- W2122884679
- Cited by
- 1,279
- References
- 18
- Citations by year
- 2026: 60 · 2025: 89 · 2024: 115 · 2023: 115 · 2022: 137 · 2021: 182 · 2020: 116 · 2019: 92 · 2018: 71 · 2017: 63 · 2016: 60 · 2015: 55 · 2014: 39 · 2013: 42 · 2012: 23
- FWCI
- 34.75
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- The Annals of Family Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- ResearchSpace (University of Auckland) (submittedVersion, cc-by)
- Funders
- Health Research Council of New Zealand
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- PHQ-2, PHQ-9, Patient Health Questionnaire, major depressive disorder, depression screening, primary care, screening sensitivity and specificity, Composite International Diagnostic Interview, threshold scores, general practice
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Major Depressive Disorder, Depressive Disorder, Major, Diagnosis, Computer-Assisted, Female, Humans, Male, Mass Screening, Middle Aged, New Zealand, Physicians, Family, Predictive Value of Tests, Primary Health Care, Psychometrics, Surveys and Questionnaires, Sensitivity and Specificity, Software, Time Factors, Prevalence, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review