Cited by 19Oral microbiology and periodontitis researchChronic Obstructive Pulmonary Disease (COPD) ResearchDental Health and Care Utilization

Correction: A Cohort Study of the Impact of Tooth Loss and Periodontal Disease on Respiratory Events among COPD Subjects: Modulatory Role of Systemic Biomarkers of Inflammation

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Barros, Silvana P., Suruki, Robert, Loewy, Zvi G., Beck, James D., Offenbacher, Steven·2013·PLoS ONE

Abstract

Background:In COPD patients, fatal and non-fatal respiratory-related events are influenced by age, severity of respiratory disease, and comorbidities.Objectives: Analyze the effects of edentulism, periodontal disease and systemic biomarkers of inflammation on the occurrence of serious fatal and non-fatal respiratory-related events among subjects with COPD.Methods: Cases were identified from Dental Atherosclerosis Risk in Communities study.Edentulism was defined as study participants without any natural teeth or implants.Participants with one or more natural teeth (comprising 11,378 subjects) were studied as dentate subjects.Periodontal disease status among dentate individuals was determined using the consensus definitions published by the joint Center for Disease Control/American Association of Periodontology working group).Adjusted Hazard Models are developed to evaluate the relationship between edentulism/periodontal disease and COPD Related Events.Models were then stratified by GOLD Stage I, II and III/IV.Serum biomarkers were also evaluated to explore the effect of systemic inflammation.Results: A statistically significant association was found between oral health status and COPD-related events, even adjusting for conditions such as hypertension, smoking and diabetes.Edentulous individuals who had been diagnosed with COPD had a higher incidence and were at greater risk of having a COPD related event (hospitalization and death) than individuals who had teeth and whose mout…

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Crossref · 10.1371/annotation/066cd415-327b-41cb-adce-3db7e5cb527d

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References 21 · Cited by 19

Authors
Barros, S. P., Suruki, R., Loewy, Z. G., Beck, J. D., & Offenbacher, S.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • GlaxoSmithKline (United States) (US)
Corresponding author
Offenbacher, Steven
Venue
PLoS ONE
Published
2013-08-26
Volume
8
Issue
8
ISSN
1932-6203 (ISSN-L)
OpenAlex
W2588629978
Cited by
19
References
21
Citations by year
2026: 1 · 2025: 1 · 2023: 4 · 2022: 2 · 2021: 5 · 2020: 1 · 2019: 3 · 2017: 1 · 2015: 1
Type
journal article
Language
en
Open access
Locations
  • PLoS ONE (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
Keywords
chronic obstructive pulmonary disease, edentulism, periodontal disease, respiratory events, systemic inflammation, interleukin-6, GOLD stage, hospitalization, mortality, oral health, comorbidities

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