Correction: Identifying and Characterizing Nodes Important to Community Structure Using the Spectrum of the Graph
Open accessAbstract
Background: Many complex systems can be represented as networks, and how a network breaks up into subnetworks or communities is of wide interest.However, the development of a method to detect nodes important to communities that is both fast and accurate is a very challenging and open problem. Methodology/Principal Findings:In this manuscript, we introduce a new approach to characterize the node importance to communities.First, a centrality metric is proposed to measure the importance of network nodes to community structure using the spectrum of the adjacency matrix.We define the node importance to communities as the relative change in the eigenvalues of the network adjacency matrix upon their removal.Second, we also propose an index to distinguish two kinds of important nodes in communities, i.e., ''community core'' and ''bridge''.Conclusions/Significance: Our indices are only relied on the spectrum of the graph matrix.They are applied in many artificial networks as well as many real-world networks.This new methodology gives us a basic approach to solve this challenging problem and provides a realistic result.
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WWOX and MAF were both prioritized for the WWOX locus, with MAF highly expressed in microglia and WWOX expressed most highly in astrocytes and neurons.
“WWOX and MAF, which surround an intergenic signal in an obesity associated locus91, were both prioritized for the WWOX locus, with MAF, another important regulator of macrophages92,93, being highly expressed in microglia in the Brain RNA-seq database, and WWOX, a high-density-lipoprotein cholesterol and triglyceride–associated gene94,95, being expressed most highly in astrocytes and neurons.”
From Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) · cites this paper as [91]
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References 36 · Cited by 130
- Authors
- Wang, Y., Di, Z., & Fan, Y.
- Affiliations
- Semmelweis University (HU)
- Corresponding author
- Fan, Ying
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-12-13
- Volume
- 6
- Issue
- 12
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3242674
- OpenAlex
- W4251417264
- Cited by
- 130
- References
- 36
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 4 · 2023: 4 · 2022: 10 · 2021: 11 · 2020: 13 · 2019: 9 · 2018: 14 · 2017: 12 · 2016: 13 · 2015: 10 · 2014: 7 · 2013: 8 · 2012: 1
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Natural Science Foundation of China (NCET-09, 70771011, 60974084, NCET-09-0228)
- Ministry of Education of the People's Republic of China
- Beijing Normal University
- Program for New Century Excellent Talents in University
- Fundamental Research Funds for the Central Universities
- Topics
- Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Complex Network Analysis Techniques
- Physical Sciences › Mathematics › Geometry and Topology › Graph theory and applications
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Graph Theory and Algorithms
- Keywords
- node importance, community structure, graph spectra, adjacency matrix eigenvalues, network centrality, bridge nodes, network topology
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