Gene Losses during Human Origins

Cited by (245)

Items 101–200 of 245

1. Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain
   Daniel R. Schrider, Andrew D. Kern · 2015 · Genome Biology and Evolution
2. Genetic variation in taste receptor pseudogenes provides evidence for a dynamic role in human evolution
   Davide S. Risso, Sergio Tofanelli, Gabriella Morini, Donata Luiselli, Dennis T. Drayna · 2014 · BMC Evolutionary Biology
3. Differential potency of drosomycin to Neurospora crassa and its mutant: implications for evolutionary relationship between defensins from insects and plants
   Bin Gao, Shunyi Zhu · 2008 · Insect Molecular Biology
4. Expression Profile and Gene Age Jointly Shaped the Genome-Wide Distribution of Premature Termination Codons in a Drosophila melanogaster Population
   Haiwang Yang, Bin He, Huijing Ma, Shun-Chern Tsaur, Chenyu Ma, Ying Wu, Chau‐Ti Ting, Yong E. Zhang · 2014 · Molecular Biology and Evolution
5. Gene loss through pseudogenization contributes to the ecological diversification of a generalist Roseobacter lineage
   Xiao Chu, Siyao Li, Sishuo Wang, Danli Luo, Haiwei Luo · 2020 · The ISME Journal
6. Positive selection targeting the cathelin-like domain of the antimicrobial cathelicidin family
   S. Zhu · 2008 · Cellular and Molecular Life Sciences
7. Evolutionary Analysis of the Contact System Indicates that Kininogen Evolved Adaptively in Mammals and in Human Populations
   Rachele Cagliani, Diego Forni, Stefania Riva, Uberto Pozzoli, M. Colleoni, Nereo Bresolin, Mario Clerici, Manuela Sironi · 2013 · Molecular Biology and Evolution
8. Rapid Turnover of Functional Sequence in Human and Other Genomes
   Chris P. Ponting, Christoffer Nellåker, Stephen Meader · 2011 · Annual Review of Genomics and Human Genetics
9. Positive selection, not negative selection, in the pseudogenization of rcsA in Yersinia pestis
   Jianzhi Zhang · 2008 · Proceedings of the National Academy of Sciences
10. Divergence, demography and gene loss along the human lineage
    Hie Lim Kim, Takeshi Igawa, Ayaka Kawashima, Yoko Satta, Naoyuki Takahata · 2010 · Philosophical Transactions of the Royal Society B Biological Sciences
11. Sequence Diversity at the Proximal 14q32.1 SERPIN Subcluster: Evidence for Natural Selection Favoring the Pseudogenization of SERPINA2
    Susana Seixas, Gianpaolo Suriano, Filipa Carvalho, Raquel Seruca, Jorge Rocha, Anna Di Rienzo · 2006 · Molecular Biology and Evolution
12. Losses of human disease-associated genes in placental mammals
    Virag Sharma, Michael Hiller · 2019 · NAR Genomics and Bioinformatics
13. The CaspBase: a curated database for evolutionary biochemical studies of caspase functional divergence and ancestral sequence inference
    Robert D. Grinshpon, Anna Williford, James E. Titus‐McQuillan, A. Clay Clark · 2018 · Protein Science
14. ACPT gene is inactivated in mammalian lineages that lack enamel or teeth
    Yuan Mu, Xin Huang, Rui Liu, Yulin Gai, Na Liang, Daiqing Yin, Lei Shan, Shixia Xu, Guang Yang · 2021 · PeerJ
15. Involvement of the chemokine-like receptor GPR33 in innate immunity
    Jens Bohnekamp, Iris Böselt, Anja Saalbach, Anke Tönjes, Peter Louis Kovacs, Heike Biebermann, Hovhannes M. Manvelyan, Tobias Polte, Daniela Gašperíková, Sodnomtsogt Lkhagvasuren et al. · 2010 · Biochemical and Biophysical Research Communications
16. Patterns of evolutionary constraints on genes in humans
    Subhajyoti De, Núria López-Bigas, Sarah Amalia Teichmann · 2008 · BMC Evolutionary Biology
17. Antagonistic Changes in Sensitivity to Antifungal Drugs by Mutations of an Important ABC Transporter Gene in a Fungal Pathogen
    Wenjun Guan, Huifeng Jiang, Xiaoxian Guo, Eugenio Mancera, Lin Xu, Yudong Li, Lars Michael Steinmetz, Yong‐Quan Li, Zhenglong Gu · 2010 · PLoS ONE
18. Convergent gene losses and pseudogenizations in multiple lineages of stomachless fishes
    Akira Kato, Supriya Pipil, Chihiro Ota, Makoto Kusakabe, Taro Watanabe, Ayumi Nagashima, An‐Ping Chen, Zinia Islam, Naoko Hayashi, Marty Kwok‐Shing Wong et al. · 2024 · Communications Biology
19. Loss and Gain of Function in SERPINB11: An Example of a Gene under Selection on Standing Variation, with Implications for Host-Pathogen Interactions
    Susana Seixas, Nevyana Ivanova, Zelia Worman, Jorge Rocha, Bruno L. Victor · 2012 · PLoS ONE
20. Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids
    Naoki Osada, Katsuyuki Hashimoto, Momoki Hirai, Jun Kusuda · 2006 · Gene
21. Human-specific antisense transcripts induced by the insertion of transposable element
    Yoonsoo Hahn · 2010 · International Journal of Molecular Medicine
22. PseudoChecker: an integrated online platform for gene inactivation inference
    Luís Q. Alves, Raquel Ruivo, Miguel M. Fonseca, Mónica Lopes‐Marques, Pedro Ribeiro, L. Filipe C. Castro · 2020 · Nucleic Acids Research
23. Modulating vertebrate physiology by genomic fine-tuning of GPCR functions
    Torsten Schöneberg · 2024 · Physiological Reviews
24. Human PTCHD3 nulls: rare copy number and sequence variants suggest a non-essential gene
    Mohammad Mahdi Ghahramani Seno, Benjamin YM Kwan, Ka Ki M Lee-Ng, Rainald Moessner, Anath Christopher Lionel, Christian R. Marshall, Stephen W. Scherer · 2011 · BMC Medical Genetics
25. Genome Sequence Comparison Reveals Independent Inactivation of the Caspase-15 Gene in Different Evolutionary Lineages of Mammals
    Leopold Eckhart · 2006 · Molecular Biology and Evolution
26. Genetics of inflammasome‐associated disorders: A lesson in the guiding principals of inflammasome function
    Ian Gaël Rodrigue‐Gervais, Maya Saleh · 2010 · European Journal of Immunology
27. All Human-Specific Gene Losses Are Present in the Genome as Pseudogenes
    Daniel R. Schrider, James C. Costello, Matthew W. Hahn · 2009 · Journal of Computational Biology
28. Correction: Corrigendum: The reverse evolution from multicellularity to unicellularity during carcinogenesis
    Han Chen, Fangqin Lin, Ke Xing, Xionglei He · 2015 · Nature Communications
29. One pedigree we all may have come from – did Adam and Eve have the chromosome 2 fusion?
    Stankiewicz, Paweł · 2016 · Molecular Cytogenetics
30. Loss of gene function and evolution of human phenotypes
    Hye Ji Oh, Dongjin Choi, Chul Jun Goh, Yoonsoo Hahn · 2015 · BMB Reports
31. Identification and analysis of unitary loss of long-established protein-coding genes in Poaceae shows evidences for biased gene loss and putatively functional transcription of relics
    Yi Chen Zhao, Liang Tang, Zhe Li, Jinpu Jin, Jingchu Luo, Ge Gao · 2015 · BMC Evolutionary Biology
32. Genome-Wide Analysis Indicates Lineage-Specific Gene Loss during Papilionoideae Evolution
    Yongzhe Gu, Shilai Xing, Chaoying He · 2016 · Genome Biology and Evolution
33. Multiple loss-of-function variants of taste receptors in modern humans
    Kohei Fujikura · 2015 · Scientific Reports
34. Repeated DNA sequences as an engine of biological diversification
    Vernata V. Grechko · 2011 · Molecular Biology
35. A Chromosome-level Genome Assembly of the Highly Heterozygous Sea UrchinEchinometrasp. EZ Reveals Adaptation in the Regulatory Regions of Stress Response Genes
    Remi N. Ketchum, Phillip L. Davidson, Edward G Smith, Gregory A. Wray, John A. Burt, Joseph F. Ryan, Adam M. Reitzel · 2022 · Genome Biology and Evolution
36. The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event
    Montserrat Hervella, Theo S. Plantinga, Santos Alonso, Bart Ferwerda, Neskuts Izagirre, Lara Fontecha Martínez, Rosa Fregel, Jos W.M. van der Meer, Concepción de la Rúa Vaca, Mihai Gheorghe Netea · 2012 · PLoS ONE
37. A possible mechanism for maintenance of the deleterious allele of human CASPASE-12
    Evan Hermel, Kevin Klapstein · 2011 · Medical Hypotheses
38. Screening for mouse genes lost in mammals with long lifespans
    Рубанов Лев Израилевич, Andrey G. Zaraisky, Gregory A. Shilovsky, А. В. Селиверстов, Oleg A. Zverkov, Vassily Lyubetsky · 2019 · BioData Mining
39. Evolution and Expression of the Immune System of a Facultatively Anadromous Salmonid
    Thomas J. Colgan, Peter A. Moran, Louise C. Archer, Robert Wynne, Stephen A. Hutton, Philip McGinnity, Thomas Eric Reed · 2021 · Frontiers in Immunology
40. Examining the Dynamic Evolution of G Protein-Coupled Receptors
    Claudia Stäubert, Diana Le Duc, Torsten Schöneberg · 2013 · Methods in pharmacology and toxicology
41. Glycan-based shaping of the microbiota during primate evolution
    Sumnima Singh, Patricia Bastos-Amador, Jessica Ann Thompson, Mauro Truglio, Bahtiyar Yılmaz, Sílvia Cardoso, Daniel Sobral, Miguel Parreira Soares · 2021 · eLife
42. Focusing on comparative ape population genetics in the post-genomic age
    Anne C. Stone, Brian C. Verrelli · 2006 · Current Opinion in Genetics & Development
43. Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation
    Daniel Divín, Mercedes Gómez-Samblás, Nithya Kuttiyarthu Veetil, Eleni Voukali, Zuzana Świderská, Tereza Krajzingrová, Martin Těšičký, Vladimı́r Beneš, Daniel Elleder, Oldřich Bartoš et al. · 2022 · Proceedings of the Royal Society B Biological Sciences
44. Presence of the functional CASPASE‐12 allele in Indian subpopulations
    Mahdieh Yavari, Garland Brinkley, Kevin Klapstein, Walter Carl Hartwig, Rammohan V. Rao, Evan Hermel · 2012 · International Journal of Immunogenetics
45. GLADX: an automated approach to analyze the lineage-specific loss and pseudogenization of genes
    Dainat, Jacques, Paganini, Julien, Pontarotti, Pierre, Gouret, Philippe · 2012 · PLoS ONE
46. Species-Specific Exon Loss in Human Transcriptomes
    Jinkai Wang, Zhixiang Lu, Collin J. Tokheim, Sara Miller, Yi Xing · 2014 · Molecular Biology and Evolution
47. Premature termination codons in modern human genomes
    Kohei Fujikura · 2016 · Scientific Reports
48. Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome
    Musaddeque Ahmed, Ping Liang · 2013 · Genomics & Informatics
49. Adaptive Gene Loss? Tracing Back the Pseudogenization of the Rabbit CCL8 Chemokine
    Wessel van der Loo, Maria J. Magalhães, Ana Lemos de Matos, Joana Abrantes, Fumio Yamada, Pedro José Esteves · 2016 · Journal of Molecular Evolution
50. Linking Fold, Function and Phylogeny: A Comparative Genomics View on Protein (Domain) Evolution
    Aartjan J.W. te Velthuis, Christoph P. Bagowski · 2008 · Current Genomics
51. Effect of Duplicate Genes on Mouse Genetic Robustness: An Update
    Zhixi Su, Junqiang Wang, Xun Gu · 2014 · BioMed Research International
52. INDELSCAN: a web server for comparative identification of species-specific and non-species-specific insertion/deletion events
    F.-C. Chen, C.-J. Chen, Trees‐Juen Chuang · 2007 · Nucleic Acids Research
53. Atherosclerosis as the Damocles’ sword of human evolution: insights from nonhuman ape-like primates, ancient human remains, and isolated modern human populations
    Annora Ai-Wei Kumar, Gavin Huangfu, Gemma A. Figtree, Girish Dwivedi · 2024 · American Journal of Physiology-Heart and Circulatory Physiology
54. Why is motilin active in some studies with mice, rats, and guinea pigs, but not in others? Implications for functional variability among rodents
    Gareth John Sanger · 2022 · Pharmacology Research & Perspectives
55. Detecting Gene Duplications in the Human Lineage
    Yuval Itan, Kevin Bryson, Mark Thomas · 2010 · Annals of Human Genetics
56. Limitations of Pseudogenes in Identifying Gene Losses
    James C. Costello, Mira Han, Matthew W. Hahn · 2008 · Lecture notes in computer science
57. Using Pseudogene Database to Identify Lineage-Specific Genes and Pseudogenes in Humans and Chimpanzees
    Qu Zhang · 2014 · Journal of Heredity
58. Sexual devolution in plants: apomixis uncloaked?
    Richard D. Noyes · 2008 · BioEssays
59. Genome-Wide Identification of Gene Loss Events Suggests Loss Relics as a Potential Source of Functional lncRNAs in Humans
    Zheng-Yang Wen, Yu-Jian Kang, Ke Lan, De-Chang Yang, Ge Gao · 2023 · Molecular Biology and Evolution
60. Evolution Reversed: The Ability To Bind Iron Restored to the N-Lobe of the Murine Inhibitor of Carbonic Anhydrase by Strategic Mutagenesis
    Anne B. Mason, Gregory L. Judson, Maria Cristina Bravo, Andrew Edelstein, Shaina L. Byrne, Nicholas G. James, Eric D. Roush, Carol A. Fierke, Cedric E. Bobst, Igor A. Kaltashov et al. · 2008 · Biochemistry
61. GENCODE Pseudogenes
    Cristina Sisu · 2021 · Methods in molecular biology
62. Nonsense Mutations in Eukaryotes
    Nadezhda A. Potapova · 2022 · Biochemistry (Moscow)
63. Computational Methods for Pseudogene Annotation Based on Sequence Homology
    Paul M. Harrison · 2021 · Methods in molecular biology
64. Human Variability and the Origins and Evolution of Language
    Terrence W. Deacon · 2016 · Elsevier eBooks
65. Positive Darwinian Selection in Gene Evolution
    Jianzhi Zhang · 2010
66. A STRUCTURAL GENOMICS APPROACH TO THE REGULATION OF APOPTOSIS: CHIMP VS. HUMAN
    Jessica Ahmed, Stefan Günther, Friedrich Möller, Robert Preißner · 2007 · International Conference on Genome Informatics (GIW)
67. Genome-scale evolution in local populations of wild chimpanzees
    Takashi Hayakawa, Takushi Kishida, Yasuhiro Go, Eiji Inoue, Eri Kawaguchi, Tomoyuki Aizu, Hinako Ishizaki, Atsushi Toyoda, Asao Fujiyama, Tetsuro Matsuzawa et al. · 2025 · Scientific Reports
68. Discovering Functional DNA Elements Using Population Genomic Information: A Proof of Concept Using Human mtDNA
    Daniel R. Schrider, Andrew D. Kern · 2014 · Genome Biology and Evolution
69. The Impact of 'Anthropotechnology' on Human Evolution
    Sylvia Blad · 2010 · Techné Research in Philosophy and Technology
70. Methods to Identify and Study the Evolution of Pseudogenes Using a Phylogenetic Approach
    Jacques Dainat, Pierre Pontarotti · 2021 · Methods in molecular biology
71. Human Lineage‐Specific Gene Inactivation
    Wendy E. Grus, Jianzhi Zhang · 2013 · Wiley eBooks
72. The Motilin Gene Evolved a New Function in Kangaroo Rats and Kangaroo Mice (Dipodomyinae)
    Jing He, Taicheng Zhou, David M. Irwin, Yongyi Shen, Ya‐Ping Zhang · 2012 · Journal of Molecular Evolution
73. Computational Methods for Pseudogene Annotation Based on Sequence Homology
    Paul M. Harrison · 2014 · Methods in molecular biology
74. Imperial botany and the early scientific breeders
    Denis J. Murphy · 2007 · Oxford University Press eBooks
75. Aspek Kepemimpinan Manajemen, Praktik Manajemen Mutu Terpadu, dan Quality Performance: Analisa PLS-Path Modeling
    F.X. Kurniawan Tjakrawala, Nurainun Bangun · 2019 · Jurnal Dinamika Akuntansi dan Bisnis
76. Primate Evolution: Gene Loss and Inactivation
    Yoko Satta · 2011 · Wiley eBooks
77. Natural Selection in Human Populations
    Amy Goldberg, Lawrence H. Uricchio, Noah A. Rosenberg · 2018 · Oxford University Press eBooks
78. Fluid genomes, uncertain species, and the genetics of crop domestication
    Denis J. Murphy · 2007 · Oxford University Press eBooks
79. Evolution of Repetitive Genomic Content and Gene Families Over Geo‐Climatic Gradients in Brassicaceae
    Jana M. Flury, Weihong Qi, Olivier Bachmann, Yvonne Willi · 2025 · Ecology and Evolution
80. Chromosomal rearrangements and segmental deletions contribute to gene loss in squamates
    Buddhabhushan Girish Salve, H Sonal, Nagarjun Vijay · 2026 · BMC Biology
81. The Power of an Evolutionary Perspective in Studies of Endocrinology
    Jing He, David M., Ya‐Ping Zhang · 2011 · InTech eBooks
82. Evolutionarily recent insertions of mobile elements and their contribution to human genome structure
    Konstantin K. Baskaev, Anton A. Buzdin · 2012 · Biology Bulletin Reviews
83. Methods to Study the Occurrence and the Evolution of Pseudogenes Through a Phylogenetic Approach
    Jacques Dainat, Pierre Pontarotti · 2014 · Methods in molecular biology
84. The domestication of non-cereal crops
    Denis J. Murphy · 2007 · Oxford University Press eBooks
85. Agricultural improvement in modern times
    Denis J. Murphy · 2007 · Oxford University Press eBooks
86. Interspecies Mixtures and the Status of Humanity
    Neville Cobbe · 2011 · Springer eBooks
87. Gene loss in plants: Evidence from genome‐wide phylogenetic analysis of thiamine pyrophosphate‐dependent enzymes
    Xinmin Tian, Peng Wang, Wen‐Bin Hu, Da‐Hai Gao, Qiong Li · 2014 · Journal of Systematics and Evolution
88. Research proceedings on primate comparative genomics
    Chenghong Liao, Bing SU · 2013 · Zoological Research
89. The domestication of cereal crops
    Denis J. Murphy · 2007 · Oxford University Press eBooks
90. Early human societies and their plants
    Denis J. Murphy · 2007 · Oxford University Press eBooks
91. Nitric oxide synthase in plants—A follow-up of ABR volume 77: Nitric oxide and signaling in plants
    David Wendehenne · 2021 · Advances in botanical research
92. A Positively Selected MAGEE2 LoF Allele Is Associated with Sexual Dimorphism in Human Brain Size and Shows Similar Phenotypes in Magee2 Null Mice
    Michał Szpak, Stephan C. Collins, Yan Li, Xiao Liu, Qasim Ayub, Marie‐Christine Fischer, Valerie E. Vancollie, Christopher J. Lelliott, Yali Xue, Binnaz Yalcin et al. · 2021 · Molecular Biology and Evolution
93. Spatial and temporal diversity of positive selection on shared haplotypes at the PSCA locus among worldwide human populations
    Risa L. Iwasaki, Yoko Satta · 2023 · Heredity
94. Linear Programming and Integer Linear Programming in Bioinformatics
    Sandro Andreotti · 2015 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
95. Human Lineage‐specific Gene Inactivation
    Wendy E. Grus, Jianzhi Zhang · 2008 · Wiley eBooks
96. Evolutionary analysis of mammalian genomes and associations to human disease
    Jessica J. Vamathevan · 2009 · OpenGrey (Institut de l'Information Scientifique et Technique)
97. Genomic Patterns of Gene Evolution.
    Margaret A. Bakewell · 2011 · Deep Blue (University of Michigan)
98. Divergence between the Human and Chimpanzee Genomes and its Impact on Protein and Transcriptome Evolution
    Hildegard Kehrer‐Sawatzki, D.N. Cooper · 2008 · Wiley eBooks
99. Models of adaptation and speciation
    Pleuni Simone Pennings · 2007 · Elektronische Hochschulschriften der LMU München (Ludwig-Maximilians-Universität München)
100. Aproximació molecular a l'estudi dels primats: Evolució dels gens RPS4Y i aplicació d'SNPs en conservació
     Olga Andrés Viñas · 2007 · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)