MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes

Cited by (272)

Items 201–272 of 272

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    Hongjoo An, Chuandong Fan, Dongkyeong Kim, Huy Bui, Yungki Park · 2025 · PLoS Genetics
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    Jack K. McDonald, Sheng Yu Ang, Christopher J. Langmead, Gregory D. Stewart · 2025 · Journal of Neurochemistry
  5. MYRF Variants in Patients With 46, XY Differences/Disorders of Sex Development and Literature Review
    Wei Zhang, Xi Wang, Jiangfeng Mao, Yaqing Cao, Xiaoxia Zhang, Min Nie, Xueyan Wu · 2025 · American Journal of Medical Genetics Part A
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  8. Activation of the Akt Attenuates Ropivacaine-Induced Myelination Impairment in Spinal Cord and Sensory Dysfunction in Neonatal Rats
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  9. Correspondence to Rossetti et al.'s review of the phenotypic spectrum associated with haploinsufficiency of MYRF
    Wenmin Sun, Xueshan Xiao, Qingjiong Zhang · 2019 · American Journal of Medical Genetics Part A
  10. The clinical overlap between cardiac‐urogenital syndrome, Meacham syndrome, and PAGOD syndrome. Report of a new patient with cardiac‐urogenital syndrome
    Daniela Alves, Miguel Leão · 2020 · American Journal of Medical Genetics Part A
  11. Myelin pathology in ataxia-telangiectasia is the cell autonomous effect of ATM deficiency in oligodendrocytes
    Tse, Kai-Hei, Cheng, Aifang, Yeung, Sunny Hoi-Sang, Ng, Jia-Nian, Cheng, Gerald Wai-Yeung, Wang, Qingyang, Zhu, Beika, Cui, Yong, Jiang, Liwen, Kofler, Julia et al. · 2021
  12. Oligodendrocyte lineage cells driven by neuronal activity in selected brain regions are required for episodic memory formation
    Luendreo P. Barboza, Benjamin Bessières, Omina Nazarzoda, Cristina M. Alberini · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  13. FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult CNS
    Hannah Y. Collins, Ryan A. Doan, Jiaxing Li, Jason J. Early, Megan Madden, Tyrell Simkins, David Anthony Lyons, Kelly R. Monk, Ben Emery · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Like a G6-nal: transcriptional control of G-protein coupled receptors during oligodendroglial development
    Tim Aberle, Michael Wegner · 2024 · Neural Regeneration Research
  15. The Intranasal Administration of Transferrin‐Loaded Extracellular Vesicles Enhances Remyelination
    Vanesa Soledad Mattera · 2025 · Journal of Neurochemistry
  16. Persistent Leukoencephalopathy Following H 1 N 1 Infection Associated With a Novel MYRF Variant (p. G ly735 A sp)
    Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian · 2025 · Annals of Clinical and Translational Neurology
  17. Integrative genomic characterization of the FADS1-2-3 mood disorder risk locus: implications for the role of polyunsaturated fatty acids
    David Stacey, William R. Reay, Liam J. Veltman, Beben Benyamin, S. Hong Lee, Elina Hyppönen · 2026 · Journal of Affective Disorders
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    Anandika Dhaliwal · 2013 · Materials and Methods
  19. A shifting adversary: control of pancreatic cancer transcriptomic subtypes
    Charles J. David · 2022 · Journal of Cancer Metastasis and Treatment
  20. LY2940094, an NOPR antagonist, promotes oligodendrocyte generation and myelin recovery in an NOPR independent manner
    Yanhui Duan, Chenyuan Ye, Jingyi Liao, Xin Xie · 2024 · Neurotherapeutics
  21. MYRF gene mutation leading to coronary artery anomaly combined with 46,XY sex development disorder, a case report and literature review
    Jianhua Ding, Zhenyu Lv, Zhen Zhen, Yong Gai, Yanyan Xiao · 2025 · BMC Pediatrics
  22. Generation and Maturation of Macroglia in the Central Nervous System
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  23. Central nervous system hypomyelination disrupts axonal conduction and behaviour in larval zebrafish
    Megan Madden, Daumante Šuminaite, Elelbin A. Ortiz, Jason J. Early, Sigrid Koudelka, Matthew R. Livesey, Isaac Henry Bianco, Michael Granato, David Anthony Lyons · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Early Deprivation Impairs Perforant Pathway Connectivity and Contextual Memory in Adolescent Male Mice
    Rafiad Islam, Jordon D. White, Tanzil Mahmud Arefin, Sameet S. Mehta, Xinran Liu, Baruh Polis, Lauryn Giuliano, Sahabuddin Ahmed, Christian Andrew Bowers, Jiangyang Zhang et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium
    Gabrielle M. Rozumek, Michelle Lynn Brinkmeier, Bin Guan, Su Qing Wang, Catherine A. Tower, Nina T. Yang, Rachel Lim, Lijin Dong, Douglas Ford Hannum, Sayoko Eileen Moroi et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans
    Zhimin Xu, Xiaoting Feng, Haochen Lyu, Yong-Hong Yan, Yongqi Zhou, Zhizhi Wang, Fang Bai, Meng‐Qiu Dong, Yingchuan Billy Qi · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Mechanisms of disrupted neurodevelopment after Zika virus infection in infancy
    Venkata Viswanadh Edara, Sienna M. Freeman, Maureen McGuirk Sampson, Kathryn Moore, Rebecca L. Richardson, Nils Schoof, Divine Burgess, Michelle Lee, Gregory Tharp, Roza Vlasova et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Characterization of transcription factors in plasmodium falciparum
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  30. MYRFs on the Move to Rewire Circuits
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  32. Purification de Protéine par chromatographie sur colonne
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  33. Computational genomics and genetics of developmental disorders
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  34. The role of apolipoprotein E in traumatic brain injury as determined by isoform and Abca1 haplodeficiency
    Emilie L. Castranio · 2018 · D-Scholarship@Pitt (University of Pittsburgh)
  35. Myelin plasticity in mouse resilience and susceptibility to psychosocial stress : implications for anxiety disorders
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  36. Evolução molecular do enhancer HACNS1 em primatas
    Gabrielle Azevedo Rizzato · 2020
  37. Pluripotent stem-cell-derived oligodendrocyte progenitors to model demyelination caused by Theiler’s murine encephalomyelitis virus and other viruses
    Eric C. Freundt, Pavan Rajanahalli · 2021 · Elsevier eBooks
  38. Methods to Identify Oligodendrocytes and Schwann cells☆
    Jacqueline Trotter, Khalad Karram · 2015 · Elsevier eBooks
  39. Faculty Opinions recommendation of Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury.
    Michael George Fehlings · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  40. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle
    Rashad Hussain, Wendy B. Macklin · 2017 · Journal of Neuroscience
  41. 柱层析蛋白质纯化方法学之综述
    Caroline Ritchie · 2012 · 实验材料和方法
  42. Ben A. Barres
    2018 · Society for Neuroscience eBooks
  43. Essential Function of Transmembrane Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development
    Zhimin Xu, Zhao Wang, Lifang Wang, Yingchuan Billy Qi · 2024 · eLife
  44. Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe
    C. Donkels, Susanne Huber, T. Demerath, C. Scheiwe, M. Shah, M. Heers, H. Urbach, A. Schulze-Bonhage, Marco Prinz, U. Häussler et al. · 2024 · bioRxiv
  45. Essential Function of Transmembrane Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development
    Zhimin Xu, Zhao Wang, Lifang Wang, Yingchuan Billy Qi · 2024 · eLife
  46. Anophthalmia, Microphthalmia, and Uveal Coloboma
    Paige M. Brooks, Brian P. Brooks · 2024 · Elsevier eBooks
  47. Cardiac-Urogenital Syndrome (CUSC)
    Linda Z. Rossetti, Daryl A. Scott · 2025 · Springer eBooks
  48. Orchestrating the neuroglial compartment: Ontogeny and developmental interaction of astrocytes, oligodendrocytes, and microglia
    Imke M. E. Schuurmans, Annika Mordelt, Lot D. de Witte · 2025 · Handbook of clinical neurology
  49. Integration of Nuclear Receptors into a Schwann cell Gene Regulatory Network
    Raghu Ramesh, Saniya Khullar, Alena J. Hanson, Seongsik Won, Camila Lopez‐Anido, Daifeng Wang, John P. Svaren · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  50. PKC-dependent MYRF dysregulation links Aβ pathology to oligodendrocyte, myelin and cognitive alterations in Alzheimer’s disease
    Uxue Balantzategi, Adhara Gaminde‐Blasco, Neus Alcañiz, Juanma Ramírez, Rodrigo Senovilla-Ganzo, Nagore Hernández-Pinedo, Mario Fernandez-Ballester, Federico Nicolás Soria, Alerie Guzman de la Fuente, Fernando García‐Moreno et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Additional file 3 of ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation
    Chen, Lu, Yu, Zhuo, Li Xie, He, Xiaoxiao, Xingmei Mu, Chen, Chiqi, Yang, Wenqian, Tong, Xiaoping, Liu, Junling, Gao, Zhengliang et al. · 2023 · Figshare
  52. Additional file 1 of Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice
    Rafiad Islam, Jordon D. White, Tanzil Mahmud Arefin, Sameet S. Mehta, Xinran Liu, Polis, Baruh, Lauryn Giuliano, Sahabuddin Ahmed, Christian Bowers, Zhang, Jiangyang et al. · 2024 · Figshare
  53. Additional file 2 of ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation
    Chen, Lu, Yu, Zhuo, Li Xie, He, Xiaoxiao, Xingmei Mu, Chen, Chiqi, Yang, Wenqian, Tong, Xiaoping, Liu, Junling, Gao, Zhengliang et al. · 2023 · Figshare
  54. Additional file 1 of ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation
    Chen, Lu, Yu, Zhuo, Li Xie, He, Xiaoxiao, Xingmei Mu, Chen, Chiqi, Yang, Wenqian, Tong, Xiaoping, Liu, Junling, Gao, Zhengliang et al. · 2023 · Figshare
  55. MYRF drives heterochronic miRNAs and LIN-42, and amplifies oscillatory programs for stage transitions
    Zhao Wang, Shiqian Shen, Xiaoting Feng, Di Chen, Qian Bian, Yingchuan Billy Qi · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  56. Reactive OPCs in CNS Injury: From Functional Diversity to Therapeutic Translation
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  57. Beyond the Wiring: White Matter as a Dynamic Regulator of Brain Function and Disease
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  58. Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos
    Gabrielle M. Rozumek, Michelle Lynn Brinkmeier, Bin Guan, Su Qing Wang, Catherine A. Tower, Nina T. Yang, Rachel S. Lim, Dejuan Kong, Daniel Soden, Qitao Zhang et al. · 2026 · JCI Insight
  59. Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans
    Zhimin Xu, Xiaoting Feng, Haochen Lyu, Yong-Hong Yan, Yongqi Zhou, Zhizhi Wang, Fang Bai, Meng‐Qiu Dong, Yingchuan Billy Qi · 2026 · eLife
  60. Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans
    Zhimin Xu, Xiaoting Feng, Haochen Lyu, Yong-Hong Yan, Yongqi Zhou, Zhizhi Wang, Fang Bai, Meng‐Qiu Dong, Yingchuan Billy Qi · 2026 · eLife
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    Muyoung Lee, Yeejin Jang, Qingqing Guo, Ujwal Punyamurtula, Joonhyuk Choi, Jonghwan Kim, Edward M. Marcotte · 2026 · Nucleic Acids Research
  67. The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice(PTN-PTPRZシグナルはオリゴデンドロサイト分化のためのAFAP1L2依存的PI3K-AKT経路を活性化する:マウスにおけるPTPRZ活性の不活化)
    Naomi Tanga · Institutional Repositories DataBase (IRDB)
  68. A Novel MYRF Variant Presenting With Scimitar Syndrome, Hepatopulmonary Fusion, Right‐Sided Congenital Diaphragmatic Hernia, and Uterine Didelphys
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  69. Crosstalk Between Oligodendrocyte Lineage Cells and CNS ‐Resident and Peripheral Immune Cells Governs Demyelination and Remyelination in Multiple Sclerosis
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  70. Oligodendrocyte‐Targeted SGK1.1 Inhibition Alleviates White Matter Injury and Cognitive Impairment in Alzheimer's Disease via Modulation of HDAC2 Phosphorylation
    Shiji Deng, Shenghan Gao, Chao Zhou, Zhen Lan, Huiya Li, Jiang Chen, Yuhao Xu, Jiashuo Li, Pinyi Liu, Siyuan Zhang et al. · 2026 · CNS Neuroscience & Therapeutics
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