APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction

Soto, Ileana, Graham, Leah C., Richter, Hannah J., Simeone, Stephen N., Radell, Jake E., Grabowska, Weronika, Funkhouser, W. Keith, Howell, Megan C. +1 more·2015·PLOS Biology

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  18. Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults
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  19. APOE ε3/ε4 and APOE ε4/ε4 genotypes drive unique gene signatures in the cortex of young mice
    Kate E. Foley, Dylan T. Garceau, Kevin P. Kotredes, Gregory W. Carter, Michael Sasner, Gareth R. Howell · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Vascular integrity and immune infiltration in SCI pain: Can exercise tip the balance?
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  21. The blood-brain barrier in aging
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  23. Age and Sex‐Related Differences in Neuroprotective Effects of Cardiovascular Endurance on Cortical Thickness and Brain Volume in Adults Across Age
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  24. Walking on the tightrope: the shared roles of the bridging pericytes in the brain
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  25. Physical activity and the brain barriers: Mechanisms of neuroprotection and disease resilience
    Julia Morys, Anna Solarz, Junqiao Mi, Monika Gilicinska, Magdalena Kostka, Małgorzata Burek, Andrzej Małecki, Michal J. Toborek, Marta Maria Nowacka-Chmielewska · 2026 · Biomedicine & Pharmacotherapy
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  27. APOE-ε4 allele load modifies the brain aging process in cognitively normal late middle aged and older adults
    Lan Lin, Yuchao Wu, Xuetao Wu, Shuicai Wu · 2019 · International Conference on Artificial Intelligence, Information Processing and Cloud Computing (AIIPCC)
  28. Development of a Neuroinformatics Pipeline and its Application to Gene-environment Interaction in Neurodegenerative Disease
    Shauna M. Overgaard · 2020 · University of Minnesota Digital Conservancy (University of Minnesota)
  29. APOE ε4 and exercise interact to influence systemic and cerebral risk factors for dementia
    Kate E. Foley, Cory A. Diemler, Amanda A. Hewes, Dylan T. Garceau, Michael Sasner, Gareth R. Howell · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Impaired drainage through capillary-venous networks contributes to age-related white matter loss
    Andy Y. Shih, Stefan Stamenković, Franca Schmid, Nicolas A. Weitermann, Kevin Takasaki, Stephanie K. Bonney, Maria J. Sosa, Yuandong Li, Hannah Benett, Yongsoo Kim et al. · 2024 · Research Square
  31. A suplementação alimentar de longo prazo com folhas de manjericão (Ocimum basilicum) induz alterações comportamentais e previne o declínio cognitivo associado à idade em camundongos
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  35. Additional file 1 of Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia
    Han, Hao, Zhao, Yawei, Junda Du, Wang, Sushan, Yang, Xuehan, Li, Weijie, Song, Jiayi, Zhang, Siwei, Zhang, Ziyi, Tan, Yongfei et al. · 2024 · Figshare
  36. Additional file 2 of Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia
    Hao Han, Zhao, Yawei, Junda Du, Wang, Sushan, Yang, Xuehan, Li, Weijie, Song, Jiayi, Zhang, Siwei, Zhang, Ziyi, Tan, Yongfei et al. · 2024 · Figshare
  37. Additional file 4 of Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia
    Hao Han, Zhao, Yawei, Junda Du, Wang, Sushan, Yang, Xuehan, Li, Weijie, Song, Jiayi, Zhang, Siwei, Zhang, Ziyi, Tan, Yongfei et al. · 2024 · Figshare
  38. Additional file 3 of Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia
    Hao Han, Zhao, Yawei, Junda Du, Wang, Sushan, Yang, Xuehan, Li, Weijie, Song, Jiayi, Zhang, Siwei, Zhang, Ziyi, Tan, Yongfei et al. · 2024 · Figshare
  39. Exercise as a Systemic Prevention and Management for Alzheimer’s Disease: Restoring Brain–Body Homeostasis Through Metabolic, Neurovascular, Anti-Inflammatory, and Regenerative Mechanisms
    Li Xiao, Jeshka Meihua Green, Mai Mochizuki, Taka Nakahara · 2026 · Cells
  40. Synergistic Effects of High-Intensity Interval Training and Omega-3 on Modulating Neuroinflammation and Improving Cognitive Function in an Alzheimer's Disease Rat Model
    Mohammad Sadegh Ebrahimi, Abdolhossein Taheri, Fardin Fatahi · 2026 · Journal of Kermanshah University of Medical Sciences