Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Kirchner, Philipp, Bourdenx, Mathieu, Madrigal-Matute, Julio, Tiano, Simoni, Diaz, Antonio, Bartholdy, Boris A., Will, Britta, Cuervo, Ana Maria·2019·PLOS Biology

Cited by (257)

Items 101–200 of 257

  1. Autophagy in Atherosclerotic Plaque Cells: Targeting NLRP3 Inflammasome for Self-Rescue
    Xuelian Li, Xianjie Zhu, Yumiao Wei · 2022 · Biomolecules
  2. Chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapy
    Yi Liu, Ming Tan, Meng‐Shan Tan · 2023 · Molecular and Cellular Biochemistry
  3. EVA1A Plays an Important Role by Regulating Autophagy in Physiological and Pathological Processes
    Shizhen Zhao, Honggang Wang · 2021 · International Journal of Molecular Sciences
  4. Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription
    Dongfang Wang, Keai Sinn Tan, Weiping Zeng, Sixu Li, Yueqi Wang, Fapeng Xu, Wen Tan · 2022 · Life Sciences
  5. Targeting chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapeutic potential
    Jin Wu, Wan Xu, Ying Su, Guanghui Wang, Jingjing Ma · 2024 · Acta Pharmacologica Sinica
  6. The Complex Role of Chaperone-Mediated Autophagy in Cancer Diseases
    Jing Liu, Lijuan Wang, Hua He, Yueying Liu, Yiqun Jiang, Jinfeng Yang · 2023 · Biomedicines
  7. Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome
    Rabia R. Khawaja, Ernesto Griego, Kristen L. Lindenau, Asma B. Salek, Jessica Gambardella, Aurora Scrivo, Hannah R. Monday, Mathieu Bourdenx, Jesús Madero‐Pérez, Zohaib N. Khan et al. · 2025 · Nature Cell Biology
  8. Lysosomal targetomics of ghr KO mice shows chaperone-mediated autophagy degrades nucleocytosolic acetyl-coA enzymes
    S. Joseph Endicott, Alexander C. Monovich, Eric L. Huang, E Henry, Dennis N. Boynton, Logan J. Beckmann, Michael J. MacCoss, Richard A. Miller · 2021 · Autophagy
  9. Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions
    William P. Miller, Congzhou Mike Sha, Siddharth Sunilkumar, Allyson L. Toro, Ashley M. VanCleave, Scot R. Kimball, Nikolay V. Dokholyan, Michael Don Dennis · 2022 · Diabetes
  10. Chaperone-mediated autophagy: mechanisms and physiological relevance
    Maryam Jafari, Mericka McCabe, Ana María Cuervo · 2022 · Current Opinion in Physiology
  11. Autophagy regulation of virus infection in aquatic animals
    Chen Li, Yunli Zhang, Xianliang Zhao, Li Li, Xianghui Kong · 2023 · Reviews in Aquaculture
  12. Pathogenic Aspects and Therapeutic Avenues of Autophagy in Parkinson’s Disease
    Rémi Kinet, Benjamin Dehay · 2023 · Cells
  13. Modulating autophagy to treat diseases: A revisited review on in silico methods
    Lifeng Wu, Wenke Jin, Haiyang Yu, Bo Liu · 2023 · Journal of Advanced Research
  14. Site-specific photo-crosslinking of Hsc70 with the KFERQ pentapeptide motif in a chaperone-mediated autophagy and microautophagy substrate in mammalian cells
    Tatsuro Seike, Kazue Terasawa, Takanori Iwata, Jun‐Lin Guan, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara‐Yokoyama · 2024 · Biochemical and Biophysical Research Communications
  15. The Role of Chaperone-Mediated Autophagy in Hepatitis C Virus-Induced Pathogenesis
    Chieko Matsui, Putu Yuliandari, Lin Deng, Takayuki Abe, Ikuo Shoji · 2021 · Frontiers in Cellular and Infection Microbiology
  16. Autophagy-Associated Immunogenic Modulation and Its Applications in Cancer Therapy
    Zhuxi Duan, Yu Shi, Qun Lin, Ahmed Hamaï, Maryam Mehrpour, Chang Gong · 2022 · Cells
  17. Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age
    Ignacio Ramírez‐Pardo, Silvia Campanario, Bhakti Chavda, Olaya Santiago‐Fernández, Marta Flández, Mercedes Grima-Terrén, Andrés Cisneros, Aina Calls, Daniel N. Itzhak, Bryan Ngo et al. · 2025 · Nature Metabolism
  18. Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis
    You‐Jin Choi, Yoon Ah Nam, Ji Ye Hyun, Jihyeon Yu, Yewon Mun, Sung Ho Yun, Wonseok Lee, Cheon Jun Park, Byung Woo Han, Byung‐Hoon Lee · 2024 · Autophagy
  19. Selective Degradation Permits a Feedback Loop Controlling Annexin A6 and Cholesterol Levels in Endolysosomes of NPC1 Mutant Cells
    Elsa Meneses‐Salas, Ana García-Melero, Patricia Blanco‐Muñoz, Jaimy Jose, Marie-Sophie Brenner, Albert Lu, Francesc Tebar, Thomas Grewal, Carles Rentero, Carlos Enrich · 2020 · Cells
  20. Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass
    Nisreen S. Akel, Ryan S. MacLeod, Stuart B. Berryhill, Dominique J. Laster, Milena Dimori, Julie A. Crawford, Qiang Fu, Melda Onal · 2022 · Scientific Reports
  21. Proteostasis, disease and the ageing neuron: Compartmental complexity in non-renewing cells
    Rosemary A Coleman, Michaela E. Johnson, Anna Konopka, Yee Lian Chew · 2026 · Ageing Research Reviews
  22. Chaperone-mediated autophagy as a modulator of aging and longevity
    S. Joseph Endicott · 2024 · Frontiers in Aging
  23. Ferroptosis triggers anti-tumor immunity via promoting chaperone-mediated autophagic degradation of SHP2
    Jiazhen Zhu, Xiaofei Li, Wenbo Chen, Zhenqi Zuo, Qin Gong, Jinbo Hu, Kai Huang, Wen Liu, Yanhong Gu, Qiang Xu et al. · 2025 · Redox Biology
  24. WDR45 mutation dysregulates iron homeostasis by promoting the chaperone-mediated autophagic degradation of ferritin heavy chain in an ER stress/p38 dependent mechanism
    Qiuhong Xiong, Huimin Sun, Wenxiu Xing, Xin Li, Guangxin Chen, Zhonghua Zhao, Changxin Wu, Ping Li · 2023 · Free Radical Biology and Medicine
  25. Pycard deficiency inhibits microRNA maturation and prevents neointima formation by promoting chaperone-mediated autophagic degradation of AGO2/argonaute 2 in adipose tissue
    Jian Li, Hongmin Yao, Fujie Zhao, Junqing An, Qilong Wang, Jing Mu, Zhixue Liu, Ming‐Hui Zou, Zhonglin Xie · 2023 · Autophagy
  26. The essential role of TTC28 in maintaining chromosomal stability via HSPA8 chaperone-mediated autophagy
    Ge Zhang, Meiyi Xiang, Liankun Gu, Jing Zhou, Baozhen Zhang, Wei Tian, Dajun Deng · 2024 · Proceedings of the National Academy of Sciences
  27. Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
    Deyu Zhang, Songze Song, Jing Lin, Tianxing Ye, Xiao Min Yang, Qiwei Jiang, Yue Mi, Mengting Zhang, Xiangwei Ge, Yanjie Shen et al. · 2025 · Developmental Cell
  28. Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress
    Yixiao Zhuang, Xinyi Zhang, Shuang Zhang, Yunpeng Sun, Hui Wang, Yuxuan Chen, Hanyin Zhang, Penglai Zou, Yonghao Feng, Xiaodan Lü et al. · 2025 · Nature Communications
  29. RETRACTED: Lysosomes in Stem Cell Quiescence: A Potential Therapeutic Target in Acute Myeloid Leukemia
    Vaibhav Jain, Swaroop N. Bose, Awadhesh Kumar Arya, Tasleem Arif · 2022 · Cancers · Retracted
  30. The critical role of the endolysosomal system in cerebral ischemia
    Ying Xu, Huiyi Zhang, Ye Tian, Han-Yan Shi, Ya Cai · 2022 · Neural Regeneration Research
  31. In vitro methods in autophagy research: Applications in neurodegenerative diseases and mood disorders
    Dalinda Isabel Sánchez-Vidaña, Jingjing Li, Samuel Abokyi, Jackie Ngai-Man Chan, Shirley P.C. Ngai, Benson Wui-Man Lau · 2023 · Frontiers in Molecular Neuroscience
  32. TRIM45 restricts influenza virus infection through modulating the chaperone-mediated autophagic degradation of viral PB2 protein
    Yihan Wang, Jiang Li, Qibing Li, Mengjie Li, Wenjun Shi, Bo Wang, Guangwen Wang, Guohua Deng, Jianzhong Shi, Guobin Tian et al. · 2025 · PLoS Pathogens
  33. Heat Therapy: Targeting Health, Disease, and Disability
    Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher Todd Minson · 2026 · Comprehensive physiology
  34. Heat and mitochondrial bioenergetics
    Alex T. Von Schulze, Paige C. Geiger · 2022 · Current Opinion in Physiology
  35. REDD1 Is a Promising Therapeutic Target to Combat the Development of Diabetes Complications: A Report on Research Supported by Pathway to Stop Diabetes
    Siddharth Sunilkumar, Michael Don Dennis · 2024 · Diabetes
  36. How to target membrane proteins for degradation: Bringing GPCRs into the TPD fold
    Bogusława Korona, Laura S. Itzhaki · 2024 · Journal of Biological Chemistry
  37. Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways
    Akiko Idera, Lisa M. Sharkey, Yuki Kurauchi, Keiichi Kadoyama, Henry Lauris Paulson, Hiroshi Katsuki, Takahiro Seki · 2023 · Journal of Pharmacological Sciences
  38. Chaperone-Mediated Autophagy in Brain Injury: A Double-Edged Sword with Therapeutic Potentials
    Huiyi Zhang, Ye Tian, Shuai Ma, Yichen Ji, Zhihang Wang, Peilun Xiao, Ying Xu · 2024 · Molecular Neurobiology
  39. Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila
    Anne‐Claire Jacomin, Raksha Gohel, Zunoon Hussain, Ágnes Varga, Tamás Maruzs, Mark Eddison, Margaux Sica, Ashish Jain, Kevin G. Moffat, Terje Johansen et al. · 2020 · Life Science Alliance
  40. Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability
    Igor Tokarchuk, Félice A. Janser, Anna M. Schläfli, Marta Teixeira Pinto, Magali Humbert, Nicolas J. Niklaus, Sabina Berezowska, Rupert Langer, Mario P. Tschan · 2021 · Biochemical and Biophysical Research Communications
  41. Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro
    Rodrigo Espinosa, Karla Gutiérrez, Javiera Ríos, Fernando Ormeño, Liliana Yantén, Pablo Galaz‐Davison, César A. Ramírez‐Sarmiento, Valentina Parra, Amelina Albornoz, Iván E. Alfaro et al. · 2022 · Cells
  42. D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation
    Erika Ueda, Tomoko Ohta, Ayumu Konno, Hirokazu Hirai, Yuki Kurauchi, Hiroshi Katsuki, Takahiro Seki · 2022 · Cells
  43. Spleen Tyrosine Kinase Contributes to Müller Glial Expression of Proangiogenic Cytokines in Diabetes
    Esma I. Yerlikaya, Allyson L. Toro, Siddharth Sunilkumar, Ashley M. VanCleave, Ming Leung, Yuka Imamura Kawasawa, Scot R. Kimball, Michael Don Dennis · 2022 · Investigative Ophthalmology & Visual Science
  44. The Multifaceted Role of CMA in Glioma: Enemy or Ally?
    Alessia Lo Dico, Cristina Martelli, Cecilia Diceglie, Luisa Ottobrini · 2021 · International Journal of Molecular Sciences
  45. Correction: Proteome-wide analysis of chaperone-mediated autophagy targeting motifs
    Philipp Kirchner, Mathieu Bourdenx, Julio Madrigal‐Matute, Simoni Tiano, Antonio Díaz, Boris Bartholdy, Britta Will, Ana María Cuervo · 2022 · PLoS Biology
  46. Chaperone-mediated autophagy controls brown adipose tissue thermogenic activity
    Alberto Mestres‐Arenas, Tania Quesada‐López, Albert Blasco‐Roset, Aleix Gavaldà‐Navarro, Francisco J. Godoy-Nieto, Rubén Cereijo, Susmita Kaushik, Antonio Díaz, Marta Giralt, Francesc Villarroya et al. · 2025 · Science Advances
  47. Defective chaperone-mediated autophagy in the retinal pigment epithelium of age-related macular degeneration patients
    Juan Ignacio Jiménez‐Loygorri, Peng Shang, Ibrahim Bayramoglu, Raquel Gómez‐Sintes, Adrián Martín‐Segura, Helena Ambrosino, Johnson Hoang, Antonio Díaz, Zhaohui Geng, Evripidis Gavathiotis et al. · 2025 · EMBO Molecular Medicine
  48. Autophagy Dysfunction: The Kernel of Hair Loss?
    Xiaofan Jin, Xiuzu Song · 2024 · Clinical Cosmetic and Investigational Dermatology
  49. Chaperone-mediated autophagy in fish: A key function amid a changing environment
    Simon Schnebert, Emilio J. Vélez, Maxime Goguet, Karine Dias, Vincent Véron, Isabel García-Pérez, Lisa M. Radler, Emilie Cardona, Stéphanie Fontagné-Dicharry, Pierre Van Delft et al. · 2024 · Autophagy Reports
  50. Recent advances in autophagic machinery: a proteomic perspective
    Xingyun Wu, Li Luo, Ruxin Kong, Yabing Song, Qifu Li, Edouard Collins Nice, Kui Wang · 2020 · Expert Review of Proteomics
  51. Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP
    Heena Saini, Mahima Choudhary, Harshita Sharma, Shibasish Chowdhury, Sudeshna Mukherjee, Rajdeep Chowdhury · 2022 · Molecular Biology Reports
  52. Chaperone-mediated autophagy regulates the metastatic state of mesenchymal tumors
    Xun Zhou, Eva Berenger, Yong Shi, Vera Shirokova, Elena Y. Kochetkova, Tina Becirovic, Boxi Zhang, Vitaliy O. Kaminskyy, Yashar Esmaeilian, Kayoko Hosaka et al. · 2025 · EMBO Molecular Medicine
  53. Heat shock protein A1 inhibits the replication of foot-and-mouth disease virus by degrading viral RNA polymerase 3D through chaperone-mediated autophagy
    Mei Ren, Haiqian Zhou, Jin’en Wu, Jia-ning Wang, Xuefei Wang, Sahibzada Waheed Abdullah, Huichen Guo, Shiqi Sun · 2025 · Journal of Virology
  54. Recent insights into HSP70: proteostasis and beyond
    Kristina Pustovaya, Artem A Venediktov, Vladislav O. Soldatov, Кузьмин Егор Александрович, Ksenia Pokidova, V. A. Gartzeva, Olga V. Payushina, Vassiliy Tsytsarev, Igor V. Meglinski, Gennadi Piavchenko · 2026 · Frontiers in Molecular Biosciences
  55. Emerging roles of mitotic autophagy
    Eugènia Almacellas, Caroline Mauvezin · 2022 · Journal of Cell Science
  56. Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B
    Ebsy Jaimon, Aashutosh Tripathi, Arohi Khurana, Dipanjana Ghosh, Jini Sugatha, Sunando Datta · 2021 · Journal of Biological Chemistry
  57. Mechanism of Tau protein incorporation into exosomes via cooperative recognition of KFERQ-like motifs by LAMP2A and HSP70
    Shan Xu, Kan Liu, Shiyan Qian, Jingying Wu, Jialing Hu, Dongming Zhou, Tingting Zheng · 2025 · Neurochemistry International
  58. Degradation Determinants Are Abundant in Human Noncanonical Proteins and Minor Annotated Isoforms
    Claudio Casola, Adekola Owoyemi, Nikolaos Vakirlis · 2026 · Genome Biology and Evolution
  59. Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy
    Kunjian Lei, Jingying Li, Zewei Tu, Chuandong Gong, Junzhe Liu, Min Hua Luo, Wenqian Ai, Lei Wu, Yishuang Li, Zhihong Zhou et al. · 2024 · Theranostics
  60. Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy
    Putu Yuliandari, Chieko Matsui, Lin Deng, Takayuki Abe, Hiroyuki Mori, Shuhei Taguwa, Chikako Ono, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji · 2022 · Autophagy Reports
  61. Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling
    Nicholas Nikesitch, Eliana Beraldi, Fan Zhang, Hans H. Adomat, Robert H. Bell, Kotaro Suzuki, Ladan Fazli, Sonia H.Y. Kung, C A Wells, Nicholas C. Pinette et al. · 2023 · Oncogene
  62. Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2
    Lisa Ehlers, Marjon Wouters, Anneleen Hombrouck, Bethany A. Pillay, Selket Delafontaine, Giorgia Bucciol, Marco Baggio, Mariia Dzhus, Emma Francés Rabanal, Alexandra Damerau et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  63. Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis
    Zachary M. Augur, Garrett M. Fogo, Mason R. Arbery, Yi‐Chen Hsieh, Nalini R. Rao, Kritika Goyal, Emily Dexter, David Alan Bennett, Jeffrey N. Savas, Andrew M. Stern et al. · 2025 · Acta Neuropathologica
  64. Activation of chaperone-mediated autophagy suppresses glioblastoma by promoting wild-type IDH1/isocitrate dehydrogenase 1 degradation
    Wanjun Tang, Bo Chen, Philip Wing‐Lok Ho, Qi‐Yu Zheng, Cherry Tsz-Yee Ng, Zhiyuan Zhu, Gkk Leung, Karrie Mei Yee Kiang · 2025 · Autophagy
  65. Co‐chaperone BAG3 enters autophagic pathway via its interaction with microtubule associated protein 1 light chain 3 beta
    Hagen Körschgen, Marius Wilhelm Baeken, Daniel Schmitt, Heike Nagel, Christian Behl · 2023 · Traffic
  66. Degradation determinants are abundant in human noncanonical proteins
    Claudio Casola, Adekola Owoyemi, Nikolaos Vakirlis · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  67. Non-enzymatic protein targeting agents as a promising strategy for cancer treatment
    Madison Ambrose, Jeremy Lee, Aleem Syed, Zamal Ahmed, Guang Peng · 2025 · Frontiers in Drug Discovery
  68. Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling
    Xiaxia Fan, Dan Guo, Songtao Li, Jinmiao Tian, Chaotong Zhang, Zhuoyu Li · 2025 · Advanced Science
  69. Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration
    Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang et al. · 2025 · Advanced Science
  70. Molecular engineering of lysosome-based degraders unveils a rapidly expanding therapeutic strategy
    Adèle Rivault, Jade Dussart‐Gautheret, Rachid Benhida, Anthony R. Martin, Patrick Auberger, Arnaud Jacquel, Guillaume Robert · 2026 · Autophagy
  71. Regulatory mechanisms for Snail protein stability: ubiquitin–proteasome system and chaperone-mediated autophagy
    Minju Kim, Keun‐Seok Hong, Taeyoung Kim, Ki‐Jun Ryu, Jiyun Yoo · 2026 · Experimental & Molecular Medicine
  72. Lipid droplet accumulation in Wdr45-deficient cells caused by impairment of chaperone-mediated autophagic degradation of Fasn
    Qiuhong Xiong, Huimin Sun, Yanlin Wang, Qian Xu, Yu Zhang, Mei Xu, Zhonghua Zhao, Ping Li, Changxin Wu · 2024 · Lipids in Health and Disease
  73. The lysosome and proteostatic stress at the intersection of pediatric neurological disorders and adult neurodegenerative diseases
    Lane-Donovan, Courtney, Paredes, Mercedes, Kao, Aimee W. · 2025 · Progress in Neurobiology
  74. Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis
    María Dolores Salinas, Carlos Manuel Martínez, Francisco Jose Roca, David García‐Bernal, Marta Martínez-Morga, Juan R. Rodríguez-Madoz, Felipe Prósper, Agustín G. Zapata, Jose Maria Moraleda, Salvador Martı́nez et al. · 2025 · Journal of Advanced Research
  75. A novel lncRNA FAM151B-DT regulates degradation of aggregation prone proteins
    Arun Renganathan, Miguel Minaya, Matthew Broder, Isabel Alfradique‐Dunham, Rebecca L. Miller, Dhruva D. Dhavale, Michelle Moritz, Reshma Bhagat, Jacob A. Marsh, Anthony C. Verbeck et al. · 2025 · Molecular Psychiatry
  76. Unraveling the intersection of aging and Parkinson’s disease: a collaborative roadmap for advancing research models
    M. Y. Schmidt, Ana María Cuervo, Kit S. Double, Dan Ehninger, M. S. Goldberg, Kirsten Harvey, Jan H.J. Hoeijmakers, K. C. Luk, Pier G. Mastroberardino, Darren J. Moore et al. · 2026 · npj Parkinson s Disease
  77. Chaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis
    Jiazhen Wang, Ru Wang, Yang Liu, Yicun Li, Peng Xian, Yuanhang Zhang, Xinning Zhang, Jiayi Wang, Chuangeng Tu, Haitao Zhang et al. · 2026 · Science Translational Medicine
  78. The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
    Xiang-Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Xiu Lu, Han‐Ming Shen · 2026 · MedComm – Oncology
  79. The emerging role and therapeutic targeting of autophagy-lysosome pathway in the pathogenesis of Parkinson’s disease
    Takahiro Shimizu, Sanem Isik, Nitika Kamath, Zhenyu Yue · 2026 · Translational Neurodegeneration
  80. Peptide-mediated inhibition of aberrant chaperone-mediated autophagy in pericytes prevents glioblastoma progression through MAPT/tau secretion
    María Dolores Salinas, Isabel María Martínez, Elena Naranjo, Maria Luisa Molina, Ana María Cuervo, Sylviane Muller, Rut Valdor · 2026 · Autophagy
  81. Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells
    Rebecca Sereda, Kristen L. Lindenau, Antonio Díaz, Zhaohui Liu, Olaya Santiago‐Fernández, Rabia R. Khawaja, Ronald R. Cutler, Jazmín Calyeca, Mericka McCabe, Sylvère Durand et al. · 2026 · Nature Aging
  82. TBBPA-BDBPE induces ferroptosis in trophoblasts through chaperone-mediated autophagy of GPX4
    Yaming Mu, Kai Wang, Yan Kang, Zhenya Fang, Shuping Yu, Jiaqi Zhou, Shuxian Li, Meihua Zhang · 2025 · Ecotoxicology and Environmental Safety
  83. An ethanol-induced loss of the lipid droplet–associated segregase VCP/p97 leads to hepatic steatosis
    Sandhya Sen, Shaun G. Weller, Ryan J. Schulze, Donglin Ding, Carol A. Casey, Conrad Chris Weihl, Mark A. McNiven · 2025 · The Journal of Cell Biology
  84. Targeting chaperone-mediated autophagy to regulate osteoclast activity as a therapeutic strategy for osteoporosis
    Yunhui Zhang, Quanfeng Li, Xiaoshuai Peng, Pengfei Ji, Yibin Zhang, Jiahao Jin, Zihao Yuan, Jianan Jiang, Guangqi Tian, Mingxi Cai et al. · 2025 · Materials Today Bio
  85. Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes
    Emilio J. Vélez, Vincent Véron, Jeanne Gouis, Steffi Reji, Karine Dias, Amaury Herpin, Florian Beaumatin, Iban Seiliez · 2025 · Scientific Reports
  86. Coupling of USP10 de-ubiquitination and chaperone-mediated autophagy causes cardiac sodium channel degradation and cardiac arrhythmias
    Hongbo Xiong, Di Guo, Zhen Zhou, Lilin Xiang, Xiangjie Kong, Tong Zhang, Zhijie Wang, Huanhuan Cai, Di Fan, Qiongxin Wang et al. · 2025 · Cardiovascular Research
  87. DYNC1LI2 regulates localization of the chaperone-mediated autophagy-receptor LAMP2A and improves cellular homeostasis in cystinosis
    Farhana Rahman, Jennifer Linda Johnson, Jinzhong Zhang, Jing Na He, Stéphanie Cherqui, Sergio Daniel Catz · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Chaperone‐Mediated Autophagy: A Critical Regulator of Neuroinflammation and Neurodegeneration
    Yingying Han, Xinyue Huang, Ying Su, Jingjing Ma, Jin Wu · 2025 · Advanced Biology
  89. Bridging structure and selectivity in chaperone‐mediated autophagy: towards targeted therapeutics
    Devid Sahu, Ishwar Patel, Kharishni Lakshman, Koyeli Mapa, Nidhi Malhotra · 2025 · FEBS Journal
  90. GRP75 blocks hepatitis E virus infection by targeting HEV-ORF2 for degradation through chaperone-mediated autophagy and promoting IRF3 activation
    Yajing Wang, Yafei Li, Rong Xu, Tong Yuan, Chenying Xu, Zhaobin Zhou, Cuiyu Ba, Qin Zhao, Chunyan Wu, Zhiru An et al. · 2025 · Journal of Virology
  91. A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy
    Taylor M. Benske, Marnie P. Williams, Pei-Pei Zhang, Adrian J. Palumbo, Ting-Wei Mu · 2026 · Journal of Biological Chemistry
  92. Chaperone-mediated autophagy is a tumor-suppressive mechanism in hepatocellular carcinoma
    Khushbu Patel, Begoña Zapatería, Alexander J. Ledet, Saba S Hazaveh, Floralba Gjergjova, Antonio Diaz, Simone Sidoli, Amaia Lujambio, Ana María Cuervo, Fernando Macián et al. · 2026 · Cell Reports
  93. Heat Therapy Can Improve Hepatic Mitochondrial Function and Glucose Control
    Chelsea N. Johnson, Reilly S. Jensen, Alex T. Von Schulze, Paige C. Geiger · 2022 · Exercise and Sport Sciences Reviews
  94. Tracking Chaperone-Mediated Autophagy Flux with a pH-Resistant Fluorescent Reporter
    Ruotong Qi, Xingyi Chen, Zihan Li, Zheng Wang, Zhuohui Xiao, Xinyue Li, Yuanyuan Han, Hongfei Zheng, Yanjun Wu, Yi Xu · 2024 · International Journal of Molecular Sciences
  95. Cerebellar Biochemistry/Pharmacology
    Takahiro Seki · 2023 · Contemporary clinical neuroscience
  96. Modern view on the role of pericytes in the microcirculation
    П. В. Михайлов, А. В. Муравьев, Irina A. Tikhomirova, Igor A. Osetrov · 2024 · Regional blood circulation and microcirculation
  97. The Role of Autophagy in Heart Disease
    Osman Mohiuddin, Sabu Abraham, Hongyuan Zhang, Andrea Ruiz‐Velasco · 2024 · International Journal of Drug Discovery and Pharmacology
  98. Rapid proteasomal degradation of the stress response protein REDD2 is mediated by the E3 ligase HUWE1
    Ashley M. VanCleave, Siddharth Sunilkumar, Christopher M. McCurry, Allyson L. Toro, Scot R. Kimball, Michael Don Dennis · 2025 · Biochemical and Biophysical Research Communications
  99. Chaperone-Mediated Autophagy in Health and Disease
    Susmita Kaushik · 2025 · Learning materials in biosciences
  100. Central activation of chaperone-mediated autophagy reduces appetite by fine-tuning hypothalamic amino acid pools: new insights from fish
    Steffi Reji, Emilio J. Vélez, Ayelén Melisa Blanco, Cécile Heraud, Vincent Véron, Karine Dias, Alexandre Stella, Odile Burlet‐Schiltz, Simon Schnebert, Jérôme Roy et al. · 2026 · American Journal of Physiology-Cell Physiology