Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

Percie du Sert, Nathalie, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T., Baker, Monya, Browne, William J., Clark, Alejandra, Cuthill, Innes C. +20 more·2020·PLOS Biology

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Items 401–500 of 2,747

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  7. Subclinical hypothyroidism contributes to poor glycemic control in patients with type 2 diabetes mellitus, and ellagic acid attenuates methimazole‐induced abnormal glucose metabolism in mice model
    Ye Liu, Xing Li, Yikun Zhu, Jiong Liu, Sunjun Liu · 2021 · Journal of Food Biochemistry
  8. Comparative transcriptomic analysis reveals an association of gibel carp fatty liver with ferroptosis pathway
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  9. Contribution of preclinical MRI to responsible animal research: living up to the 3R principle
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  10. Disbalance of the Duodenal Epithelial Cell Turnover and Apoptosis Accompanies Insensitivity of Intestinal Redox Homeostasis to Inhibition of the Brain Glucose-Dependent Insulinotropic Polypeptide Receptors in a Rat Model of Sporadic Alzheimer’s Disease
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  11. Oral vaccination of piglets against Mycoplasma hyopneumoniae using silica SBA-15 as an adjuvant effectively reduced consolidation lung lesions at slaughter
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  12. Raman Spectroscopy as a Neuromonitoring Tool in Traumatic Brain Injury: A Systematic Review and Clinical Perspectives
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  14. Altered Secretion, Constitution, and Functional Properties of the Gastrointestinal Mucus in a Rat Model of Sporadic Alzheimer’s Disease
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  15. The effect of the head-up position on cardiopulmonary resuscitation: a systematic review and meta-analysis
    Cheng‐Chieh Huang, Kuan-Chih Chen, Zih-Yang Lin et al. · 2021 · Critical Care
  16. Regulatory considerations for animal studies of biomaterial products
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  17. The impact of bio-logging on body weight change of the Eurasian beaver
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  18. What has preclinical systematic review ever done for us?
    Ash Russell, Brad A. Sutherland, Lila M. Landowski, Malcolm Robert Macleod, David William Howells · 2022 · BMJ Open Science
  19. Haematological and biochemical reference intervals for wild green turtles (Chelonia mydas): a Bayesian approach for small sample sizes
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  20. Hypoxia-triggered O-GlcNAcylation in the brain drives the glutamate–glutamine cycle and reduces sensitivity to sevoflurane in mice
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  21. Understanding the importance of quality control and quality assurance in preclinical PET/CT imaging
    Wendy McDougald, Julia G. Mannheim · 2022 · EJNMMI Physics
  22. Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart–brain dysfunctions in adulthood
    Katherine A. Leyba, Nitchawat Paiyabhroma, John P. Salvas et al. · 2023 · Acta Physiologica
  23. Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study
    Nabil V. Sayour, Gábor B Brenner, András Makkos, Bernadett Kiss, Csenger Kovácsházi, Tamás G. Gergely, Sverre Groever Aukrust, Huimin Tian, Viktória Zenkl, Kamilla Gömöri et al. · 2023 · Cardiovascular Research
  24. Ferritinophagy was involved in long-term SiNPs exposure induced ferroptosis and liver fibrosis
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  26. Nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, COX-2, and diminution of AChE, BDNF and NGF levels in cerebral cortex and hippocampus of male albino rats
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  28. Changes in the equine facial repertoire during different orthopedic pain intensities
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  30. Open Transparent Communication about Animals in Laboratories: Dialog for Multiple Voices and Multiple Audiences
    Larry Carbone · 2021 · Animals
  31. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model
    Robert T. Kleven, Kunal B. Karani, Nicole Hilvert, Samantha M. Ford, Karla P. Mercado‐Shekhar, John M. Racadio, Marepalli Bhaskara Rao, Todd A. Abruzzo, Christy K. Holland · 2021 · Scientific Reports
  32. CBF oscillations induced by trigeminal nerve stimulation protect the pericontusional penumbra in traumatic brain injury complicated by hemorrhagic shock
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  33. Resolvins as a Treatment Modality in Experimental Periodontitis: A Systematic Review of Preclinical Studies
    Nouf Al‐Shibani · 2022 · Cureus
  34. Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI
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  37. Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL-AD preclinical testing core study
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  38. CAF to the Rescue! Potential and Challenges of Combination Antifungal Therapy for Reducing Morbidity and Mortality in Hospitalized Patients With Serious Fungal Infections
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  39. A systematic review and meta-analysis of the effects of probiotics on bone outcomes in rodent models
    Jenalyn L. Yumol, William Gittings, Russell J. de Souza, Wendy Elizabeth Ward · 2024 · Journal of Bone and Mineral Research
  40. Trimethylamine N-Oxide (TMAO) Acts as Inhibitor of Endothelial Nitric Oxide Synthase (eNOS) and Hampers NO Production and Acetylcholine-Mediated Vasorelaxation in Rat Aortas
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  41. A primitive type of renin-expressing lymphocyte protects the organism against infections
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  42. Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses
    Alexander J. Dwyer, Jacob M. Ritz, Jason S. Mitchell · 2021 · Scientific Reports
  43. Chronic Pharmacological Modulation of Mitochondrial Dynamics Alleviates Prediabetes-Induced Myocardial Ischemia–Reperfusion Injury by Preventing Mitochondrial Dysfunction and Programmed Apoptosis
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  44. Posttraumatic Osteoarthritis Damage in Mice: From Histological and Micro–Computed Tomodensitometric Changes to Gait Disturbance
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  45. Intracellular and Intercellular Gene Regulatory Network Inference From Time-Course Individual RNA-Seq
    Makoto Kashima, Yuki Shida, Takashi Yamashiro, Hiromi Hirata, Hiroshi Kurosaka · 2021 · Frontiers in Bioinformatics
  46. Physiological Reloading Recovers Histologically Disuse Atrophy of the Articular Cartilage and Bone by Hindlimb Suspension in Rat Knee Joint
    Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki, Masahiro Hoso · 2021 · Cartilage
  47. Oxidized low-density lipoprotein receptor 1: a novel potential therapeutic target for intracerebral hemorrhage
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  48. Biological Behavior of Xenogenic Scaffolds in Alcohol-Induced Rats: Histomorphometric and Picrosirius Red Staining Analysis
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  49. Neuro-molecular characterization of fish cleaning interactions
    Sandra Ramirez‐Calero, José Ricardo Paula, Eve Otjacques, Rui Rosa, Timothy Ravasi, Celia Schunter · 2022 · Scientific Reports
  50. Dose-Dependent Antidepressant-Like Effects of Cannabidiol in Aged Rats
    Elena Hernández‐Hernández, María Julia García-Fuster · 2022 · Frontiers in Pharmacology
  51. Bacterial invasion into the epidermis of rats with sodium lauryl sulphate‐irritated skin increases damage and induces incontinence‐associated dermatitis
    Sofoklis Koudounas, Takeo Minematsu, Yuko Mugita · 2022 · International Wound Journal
  52. Effects of different duck rearing systems on egg flavor and quality and microbial diversity
    Xuefeng Shi, Mingyi Huang, Jianlou Song · 2022 · Poultry Science
  53. Supplementation of mixed doses of glutamate and glutamine can improve the growth and gut health of piglets during the first 2 weeks post-weaning
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  54. Genome-wide association study reveals genetic loci and candidate genes for meat quality traits in a four-way crossbred pig population
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  56. No detectable changes in anxiety-related and locomotor behaviors in adult ovariectomized female rats exposed to estradiol, the ERβ agonist DPN or the ERα agonist PPT
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  58. OECD-407 Driven 28-day-repeated-dose non-clinical safety evaluation of Tinospora cordifolia (Giloy) stem aqueous extract in Sprague-Dawley rats under GLP compliance
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  59. Large-scale industrial plantations are more likely than smallholdings to threaten biodiversity from oil palm replanting spatial disturbances
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  60. Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes
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  61. Doxorubicin-Loaded Platelet Decoys for Enhanced Chemoimmunotherapy Against Triple-Negative Breast Cancer in Mice Model
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  62. Neuromechanical Strategies for Obstacle Negotiation during Overground Locomotion following Incomplete Spinal Cord Injury in Adult Cats
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  63. The CXCL12-CXCR4-NLRP3 axis promotes Schwann cell pyroptosis and sciatic nerve demyelination in rats
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  64. Neurotoxicity of melittin: Role of mitochondrial oxidative phosphorylation system in synaptic plasticity dysfunction
    Dan Sun, Shanshan Li, Haiqin Huang, Lixing Xu · 2023 · Toxicology
  65. Possible role of selenium in ameliorating lead-induced neurotoxicity in the cerebrum of adult male rats: an experimental study
    Abdelmonem Awad Hegazy, Ayat M. Domouky, Fatma Akmal, Dalia Ibrahim El-Wafaey · 2023 · Scientific Reports
  66. Human embryonic and fetal biobanking: Establishing the Dutch Fetal Biobank and a framework for standardization
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  67. Effects of ketone body 3-hydroxybutyrate on cardiac and mitochondrial function during donation after circulatory death heart transplantation
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  68. Untargeted metabolomic profiling of serum from client-owned cats with early and late-stage chronic kidney disease
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  73. Development of synergistic antifungal in situ gel of miconazole nitrate loaded microemulsion as a novel approach to treat vaginal candidiasis
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  77. Non-invasive, non-pharmacological/bio-technological interventions towards neurorestoration upshot after ischemic stroke, in adults—systematic, synthetic, literature review
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  78. Effects of targeted muscle reinnervation on spinal cord motor neurons in rats following tibial nerve transection
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  79. Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats
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  80. Neuroprotection by Ozanimod Following Intracerebral Hemorrhage in Mice
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  82. Pharmacologically targeting transient receptor potential channels for seizures and epilepsy: Emerging preclinical evidence of druggability
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  84. Presubiculum principal cells are preserved from degeneration in knock-in APP/TAU mouse models of Alzheimer’s disease
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  85. Role of anterior segment optical coherence tomography angiography in the assessment of acute chemical ocular injury: a pilot animal model study
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  86. Nicotinamide Riboside Neutralizes Hypothalamic Inflammation and Increases Weight Loss Without Altering Muscle Mass in Obese Rats Under Calorie Restriction: A Preliminary Investigation
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  87. Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress
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  88. A systematic review on the reporting quality in mouse telemetry implantation surgery using electrocardiogram recording devices
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  89. Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak
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  90. Biofluorescent sexual dimorphism revealed in a southern Appalachian endemic salamander, Plethodon metcalfi
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  91. Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology
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  92. SIRT3 improves alveolar epithelial cell damage caused by bronchopulmonary dysplasia through deacetylation of FOXO1
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  96. Modulation of blood redox status by the progression of induced apical periodontitis in rats
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  97. Cardiovascular decline in offspring during the perinatal period in an ovine model of fetal growth restriction
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  98. Allelic effects on uromodulin aggregates drive autosomal dominant tubulointerstitial kidney disease
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