The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Balancing Selection and Its Effects on Sequences in Nearby Genome Regions
Open accessAbstract
Our understanding of balancing selection is currently becoming greatly clarified by new sequence data being gathered from genes in which polymorphisms are known to be maintained by selection. The data can be interpreted in conjunction with results from population genetics models that include recombination between selected sites and nearby neutral marker variants. This understanding is making possible tests for balancing selection using molecular evolutionary approaches. Such tests do not necessarily require knowledge of the functional types of the different alleles at a locus, but such information, as well as information about the geographic distribution of alleles and markers near the genes, can potentially help towards understanding what form of balancing selection is acting, and how long alleles have been maintained.
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Citations
Cites
Detecting recent positive selection in the human genome from haplotype structure
Sabeti, P. C., Reich, D. E., Higgins, J. M., Levine, H. Z. P., Richter, D. J., Schaffner, S. F., Gabriel, S. B., Platko, J. V., Patterson, N. J., McDonald, G. J., et al. (2002) · Nature · doi:10.1038/nature01140 · Cited by 2,106
Extended linkage disequilibrium surrounding the hemoglobin E variant due to malarial selection
Ohashi, J., Naka, I., Patarapotikul, J., Hananantachai, H., Brittenham, G., Looareesuwan, S., Clark, A. G., & Tokunaga, K. (2004) · The American Journal of Human Genetics · doi:10.1086/421330 · Cited by 137
Cited by
Cruickshank, T. E., & Hahn, M. W. (2014) · Molecular Ecology · doi:10.1111/mec.12796 · Cited by 1,061
Detecting Natural Selection in Genomic Data
Vitti, J. J., Grossman, S. R., & Sabeti, P. C. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133526 · Cited by 694
Kryukov, G. V., Pennacchio, L. A., & Sunyaev, S. R. (2007) · The American Journal of Human Genetics · doi:10.1086/513473 · Cited by 598
Gazal, S., Finucane, H. K., Furlotte, N. A., Loh, P.-R., Palamara, P. F., Liu, X., Schoech, A., Bulik-Sullivan, B., Neale, B. M., Gusev, A., et al. (2017) · Nature Genetics · doi:10.1038/ng.3954 · Cited by 525
Genetic architecture: the shape of the genetic contribution to human traits and disease
Timpson, N. J., Greenwood, C. M. T., Soranzo, N., Lawson, D. J., & Richards, J. B. (2018) · Nature Reviews Genetics · doi:10.1038/nrg.2017.101 · Cited by 434
Metadata
- Authors
- Charlesworth, D.
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2006-04-28
- Volume
- 2
- Issue
- 4
- Pages
- e64
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- OpenAlex
- W2039435867
- Cited by
- 717
- References
- 2
- FWCI
- 14.14
- Type
- journal article
- Language
- en
- Open access
- gold
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