Cited by 1,486Tuberculosis Research and EpidemiologyDiagnosis and treatment of tuberculosisInfectious Diseases and Tuberculosis

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies

Open access

Jeon, Christie Y, Murray, Megan B·2008·PLoS Medicine

DOI 10.1371/journal.pmed.0050152PMC PMC2459204

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Several studies have suggested that diabetes mellitus (DM) increases the risk of active tuberculosis (TB). The rising prevalence of DM in TB-endemic areas may adversely affect TB control. We conducted a systematic review and a meta-analysis of observational studies assessing the association of DM and TB in order to summarize the existing evidence and to assess methodological quality of the studies. METHODS AND FINDINGS: We searched the PubMed and EMBASE databases to identify observational studies that had reported an age-adjusted quantitative estimate of the association between DM and active TB disease. The search yielded 13 observational studies (n = 1,786,212 participants) with 17,698 TB cases. Random effects meta-analysis of cohort studies showed that DM was associated with an increased risk of TB (relative risk = 3.11, 95% CI 2.27-4.26). Case-control studies were heterogeneous and odds ratios ranged from 1.16 to 7.83. Subgroup analyses showed that effect estimates were higher in non-North American studies. CONCLUSION: DM was associated with an increased risk of TB regardless of study design and population. People with DM may be important targets for interventions such as active case finding and treatment of latent TB and efforts to diagnose, detect, and treat DM may have a beneficial impact on TB control.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1371/journal.pmed.0050152

Cites

47 of 47 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623
Operating characteristics of a rank correlation test for publication bias
Begg, C. B., & Mazumdar, M. (1994) · Biometrics · doi:10.2307/2533446 · Cited by 16,955
Global Prevalence of Diabetes
Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1047 · Cited by 15,297
The combination of estimates from different experiments
Cochran, W. G. (1954) · Biometrics · doi:10.2307/3001666 · Cited by 5,380
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703
Infection and diabetes: The case for glucose control
Rayfield, E. J., Ault, M. J., Keusch, G. T., BROTHERS, M. J., Nechemias, C., & Smith, H. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90511-3 · Cited by 628
Glucocorticoid use, other associated factors, and the risk of tuberculosis
Jick, S. S., Lieberman, E. S., Rahman, M. U., & Choi, H. K. (2006) · Arthritis Care & Research · doi:10.1002/art.21705 · Cited by 477

Flagged first, then by citations

Show all 47 references

Research works printed but not linked: 48

Banyai, 1931, Am Rev Tuberc, 24, 650
Root, 1934, New Engl J Med, 210, 1
Boucot, 1952, Am Rev Tuberc, 65, 1
Nichols, 1957, Am Rev Tuberc, 76, 1016
Silwer, 1958, Acta Med Scand Suppl, 335, 1
Kim, 1995, Tuber Lung Dis, 76, 529
Pablos-Mendez, 1997, Am J Public Health, 87, 574
Ponce-De-Leon, 2004, Diabetes Care, 27, 1584
Alisjahbana, 2006, Int J Tuberc Lung Dis, 10, 696
Perez, 2006, Am J Trop Med Hyg, 74, 604
Oluboyo, 1990, Tubercle, 71, 135
Basoglu, 1999, Monaldi Arch Chest Dis, 54, 307
Restrepo, 2007, Clin Inf Dis, 45, 436
Stevenson, 2007, BMC Public Health, 7, 234
Dixon, 2007, Lancet Infect Dis, 7, 444
Wild, 2004, Diabetes Care, 27, 1047
Stroup, 2000, JAMA, 283, 2008
Cochran, 1954, Biometrics, 10, 101
Higgins, 2002, Stat Med, 21, 1539
DerSimonian, 1986, Control Clin Trials, 7, 177
Greenland, 1982, Am J Epidemiol, 116, 547
Dyck, 2007, Can J Public Health, 98, 55
Begg, 1994, Biometrics, 50, 1088
Egger, 1997, BMJ, 315, 629
Chen, 2006, Transpl Infect Dis, 8, 148
Brassard, 2006, Clin Infect Dis, 43, 717
John, 2001, Kidney Int, 60, 1148
Jick, 2006, Arthritis Rheum, 55, 19
Mori, 1992, Arch Intern Med, 152, 547
Buskin, 1994, Am J Public Health, 84, 1750
Rosenman, 1996, Am J Ind Med, 30, 148
Coker, 2006, BMJ, 332, 85
Lienhardt, 2005, Int J Epidemiol, 34, 914
Mugusi, 1990, Tubercle, 71, 271
Abe, 2003, J Infect, 46, 215
Al Kubaisy, 2003, East Mediterr Health J, 9, 675
Tocque, 2001, Eur Respir J, 18, 959
Stevenson, 2007, Chronic Illn, 3, 228
Lienhardt, 1997, Int J Tuberc Lung Dis, 1, 196
Yamashiro, 2005, Clin Exp Immunol, 139, 57
Martens, 2007, Am J Respir Cell Mol Biol, 37, 518
Viardot, 2007, Endocrinology, 148, 346
Stalenhoef, 2008, Eur J Clin Microbiol Infect Dis, 27, 97
Tsukaguchi, 1997, Kekkaku, 72, 617
Delamaire, 1997, Diabet Med, 14, 29
Rayfield, 1982, Am J Med, 72, 439
Feinstein, 1986, J Chron Dis, 39, 495
Harris, 1998, Diabetes Care, 21, 518

Sorted by citations

Items 801–900 of 1,001

Artificial intelligence-reported chest X-ray findings of culture-confirmed pulmonary tuberculosis in people with and without diabetes
Geric, C., Majidulla, A., Tavaziva, G., Nazish, A., Saeed, S., Benedetti, A., Khan, A. J., & Khan, F. A. (2023) · Journal of Clinical Tuberculosis and Other Mycobacterial Diseases · doi:10.1016/j.jctube.2023.100365 · Cited by 9
How can tuberculosis services better support patients with a diabetes co-morbidity? A mixed methods study in the Philippines
Hashiguchi, L. O., Cox, S. E., Edwards, T., Castro, M. C., Khan, M. S., & Liverani, M. (2023) · BMC Health Services Research · doi:10.1186/s12913-023-10015-7 · Cited by 9
Costs incurred by people with co-morbid tuberculosis and diabetes and their households in the Philippines
Yamanaka, T., Castro, M. C., Ferrer, J. P., Solon, J. A., Cox, S. E., Laurence, Y. V., & Vassall, A. (2024) · PLoS ONE · doi:10.1371/journal.pone.0297342 · Cited by 9
Tuberculosis and diabetes mellitus comorbidity in an adult Ugandan population
Kibirige, D., Biraro, I. A., Olum, R., Adakun, S. A., Zawedde‐Muyanja, S., Sekaggya‐Wiltshire, C., & Kimuli, I. (2024) · BMC Infectious Diseases · doi:10.1186/s12879-024-09111-8 · Cited by 9
Evaluation of Active Pulmonary Tuberculosis Among Patients With Diabetes
Kermansaravi, F., Metanat, M., & Sharifi‐Mood, B. (2014) · International Journal of Infection · doi:10.17795/iji-19632 · Cited by 9
Clinical characteristics and treatment outcomes of tuberculosis cases hospitalised in the intensive phase in Fiji
Alo, A., Gounder, S., & Graham, S. M. (2014) · Public Health Action · doi:10.5588/pha.14.0022 · Cited by 9
Diabetes as an increasingly common comorbidity among patient hospitalizations for tuberculosis in the USA
Zahr, R., Peterson, R., Polgreen, L. A., Cavanaugh, J. E., Hornick, D. B., Winthrop, K. L., & Polgreen, P. M. (2016) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2016-000268 · Cited by 9
A study on prevalence of diabetes and associated risk factors among diagnosed tuberculosis patients registered under Revised National Tuberculosis Control Programme in Bhopal District
Nagar, V., Gour, D., Pal, D., Singh, A. R., Joshi, A., & Dave, L. (2018) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_289_17 · Cited by 9
Coverage of tuberculosis and diabetes mellitus screening among household contacts of tuberculosis patients: a household-based cross-sectional survey from Southern Thailand
Oo, M. M., Tassanakijpanich, N., Phyu, M. H., Safira, N., Kandel, S., Chumchuen, K., Zhang, L. M., Kyu, H. A., Sriwannawit, P., Bilmumad, B., et al. (2020) · BMC Public Health · doi:10.1186/s12889-020-09090-w · Cited by 9
Latent M. tuberculosis infection is associated with increased inflammatory cytokine and decreased suppressor of cytokine signalling (SOCS)‐3 in the diabetic host
Masood, K. I., Irfan, M., Masood, Q., Yameen, M., Jamil, B., Ram, N., Rao, S., Rottenberg, M. E., & Hasan, Z. (2021) · Scandinavian Journal of Immunology · doi:10.1111/sji.13134 · Cited by 9
Risk factors of tuberculosis in Mizoram: First report of the possible role of water source
Sailo, C. V., Tonsing, M. V., Sanga, Z., Chhakchhuak, Z., Kharkongor, F., Fela, V., Chhakchhuak, L., Lalremruata, R., Nemi, L., & Kumar, N. S. (2022) · Indian Journal of Tuberculosis · doi:10.1016/j.ijtb.2022.03.003 · Cited by 9
A Proposed India-Specific Algorithm for Management of Type 2 Diabetes
India Diabetes Management Algorithm Proposal Group (2016) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2015.0308 · Cited by 9
Prevalence and surveillance of tuberculosis in Yemen from 2006 to 2018
Al-Shehari, W. A., Yin, Y.-A., Wang, X., Wang, Y., Sun, H., Fu, Y., & Zhang, F. (2022) · Epidemiology and Infection · doi:10.1017/s0950268822001261 · Cited by 9
Tuberculosis (TB) Aftermath: study protocol for a hybrid type I effectiveness-implementation non-inferiority randomized trial in India comparing two active case finding (ACF) strategies among individuals treated for TB and their household contacts
Cox, S. R., Kadam, A. B., Atre, S. R., Gupte, A., Sohn, H., Gupte, N., Sawant, T., Mhadeshwar, V., Thompson, R. R., Kendall, E. A., et al. (2022) · Trials · doi:10.1186/s13063-022-06503-6 · Cited by 11
Effect of oral N-acetyl cysteine supplementation in type 2 diabetic patients on intracellular glutathione content and innate immune responses to Burkholderia pseudomallei
Gamage, A. M., Lee, K., & Gan, Y. (2014) · Microbes and Infection · doi:10.1016/j.micinf.2014.07.007 · Cited by 9
CT findings of TB in diabetic and non-diabetic patients: A comparison before and after anti-tuberculous therapy
Wu, H., Asad, U., Wu, J., Zhang, G., Zhang, G., & Lu, X. (2016) · Radiology of Infectious Diseases · doi:10.1016/j.jrid.2016.01.003 · Cited by 9
Diabetes Among United States-Bound Adult Refugees, 2009–2014
Benoit, S. R., Gregg, E. W., Zhou, W., & Painter, J. A. (2016) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-016-0381-7 · Cited by 10
Grupo PrevInfad/PAPPS Infancia y Adolescencia
PrevInfad, G., Faura, S., Revuelta, J. C., Rico, O. C., Ventura, J., Aguado, J. G., Rubio, A., & Bosch, J. P. (2011) · Cited by 9
Prevalence of Tuberculosis Disease Among Adult US-Bound Refugees with Chronic Kidney Disease
Bardenheier, B. H., Pavkov, M. E., Winston, C. A., Klosovsky, A., Yen, C., Benoit, S. R., Gravenstein, S., Posey, D. L., & Phares, C. R. (2019) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-018-00852-8 · Cited by 9
GeneXpert of stool versus gastric lavage fluid for the diagnosis of pulmonary tuberculosis in severely ill adults
Liu, R., Liang, Q., Shang, Y., Ma, Y., Wang, F., Dong, L., Huang, H., Gao, M., & Pang, Y. (2019) · Infection · doi:10.1007/s15010-019-01295-5 · Cited by 9
Strategic investment in tuberculosis control in the Republic of Bulgaria
Doan, T. N., Varleva, T., Zamfirova, M., Tyufekchieva, M., Keshelava, A., Hristov, K., Yaneva, A., Gadzheva, B., Zhang, S., Irbe, S., et al. (2019) · Epidemiology and Infection · doi:10.1017/s0950268819001857 · Cited by 9
Glibenclamide alters interleukin-8 and interleukin-1β of primary human monocytes from diabetes patients against Mycobacterium tuberculosis infection
Kewcharoenwong, C., Saenwongsa, W., Willcocks, S., Bancroft, G. J., Fletcher, H. A., & Lertmemongkolchai, G. (2020) · Tuberculosis · doi:10.1016/j.tube.2020.101939 · Cited by 9
Proteomic profiling of peripheral blood mononuclear cells isolated from patients with tuberculosis and diabetes copathogenesis - A pilot study
Kundu, J., Bakshi, S., Joshi, H., Bhadada, S. K., Verma, I., & Sharma, S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233326 · Cited by 9
A Mathematical Model for the Study of Effectiveness in Therapy in Tuberculosis Taking into Account Associated Diseases
Moya, E. M. D., Piétrus, A., & Oliva, S. M. (2021) · Contemporary Mathematics · doi:10.37256/cm.212021694 · Cited by 9
Optima TB: A tool to help optimally allocate tuberculosis spending
Goscé, L., Jaoude, G. J. A., Kedziora, D. J., Benedikt, C. J., Hussain, A., Jarvis, S., Skrahina, A. M., Klimuk, D., Hurevich, H., Zhao, F., et al. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009255 · Cited by 9
Diabetes and tuberculosis: A n important relationship
Bloomgarden, Z. T., & Misra, A. (2017) · Journal of Diabetes · doi:10.1111/1753-0407.12547 · Cited by 9
Minding the Gap: Specimen Referral Systems for Diagnosis of Infectious Diseases
Dowdy, D. W. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw820 · Cited by 9
Advances in understanding immune homeostasis in latent tuberculosis infection
Niu, L., Wang, H., Luo, G., Zhou, J., Hu, Z., & Yan, B. (2024) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1643 · Cited by 8
Nano-strategies used for combatting the scourge of tuberculosis infections
Fang, R., Jin, Y., Kong, W., Wang, H., Wang, S., Li, X., Xing, J., Zhang, Y., Yang, X., & Song, N. (2024) · Discover Immunity. · doi:10.1007/s44368-024-00007-y · Cited by 8
Distinct Clinical Features of Extrapulmonary and Disseminated Tuberculosis in HIV- and Non-HIV-Associated Immunosuppression: A Retrospective Cohort Study
Aceves-Sánchez, B., Rajme‐López, S., Martínez-Guerra, B. A., Rivera-Villegas, H., Román-Montes, C. M., Tamez-Torres, K. M., González-Vázquez, L. E., Guadarrama-Torres, S., Lazcano-Delgadillo, O., Nares-López, R., et al. (2025) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaf239 · Cited by 8
Drug-resistant tuberculosis: a priority pathogen for enhanced public health research and practice
Yapa, H. M., MacLean, E. L.-H., Menzies, N. A., Dodd, P. J., Dean, A. S., Mirzayev, F., Schumacher, S. G., Nguyen, L. N., Zignol, M., & Fox, G. J. (2025) · Clinical Microbiology Reviews · doi:10.1128/cmr.00064-25 · Cited by 8
SNPs in Genes Related to DNA Damage Repair in Mycobacterium Tuberculosis: Their Association with Type 2 Diabetes Mellitus and Drug Resistance
Pérez-Martínez, D. E., Bermudez-Hernández, G. A., Madrazo-Moya, C. F., Cancino‐Muñoz, I., Montero, H., Licona‐Cassani, C., Muñiz‐Salazar, R., Comas, I., & Zenteno‐Cuevas, R. (2022) · Genes · doi:10.3390/genes13040609 · Cited by 8
Experiences and perceptions of participants on the pathway towards clinical management of dual tuberculosis and diabetes mellitus in Tanzania
Chamba, N. G., Byashalira, K. C., Christensen, D. L., Ramaiya, K. L., Kapyolo, E. P., Shayo, P. J., Lillebæk, T., Ntinginya, N. E., Mmbaga, B. T., Bygbjerg, I. C., et al. (2022) · Global Health Action · doi:10.1080/16549716.2022.2143044 · Cited by 8
Impact of hyperglycemia on tuberculosis treatment outcomes: a cohort study
Xu, Y., Yang, Y., Xiaoqing, W., Zhixuan, L., Kuan, Z., Xin, G., Zhang, B., Jinyu, W., Cai, J., Ma, Y., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-64525-3 · Cited by 8
Tuberculosis survivors and the risk of cardiovascular disease: analysis using a nationwide survey in Korea
Yang, J., Kim, S., Sim, J. K., Gu, S., Seok, J. W., Bae, D., Cho, J. Y., Lee, K. M., Choe, K. H., Lee, H. J., et al. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1364337 · Cited by 8
Clinical Manifestations and Outcome of Tuberculosis in Diabetic Patients Admitted to King Abdulaziz University Hospital in Jeddah, Saudi Arabia
Siddiqui, A. M. (2009) · Journal of Taibah University Medical Sciences · doi:10.1016/s1658-3612(09)70103-9 · Cited by 8
Tuberculosis, HIV/AIDS and Diabetes – Is it Time to Think Together?
Sekar, R., & Mythreyee, M. (2012) · Journal of Medical Microbiology & Diagnosis · doi:10.4172/2161-0703.1000e103 · Cited by 8
The Global Prevalence and Incidence of Diabetes Mellitus and Pulmonary Tuberculosis
Firănescu, A.-G., Popa, A., Sandu, M.-M., Timofticiuc, D. C. P., Popa, S. G., & Moța, M. (2016) · Romanian Journal of Diabetes Nutrition and Metabolic Diseases · doi:10.1515/rjdnmd-2016-0038 · Cited by 8
Factores de riesgo para el desarrollo de Tuberculosis multidrogorresistente en Colombia, 2008 a 2011
Curtidor, L. E. F., Bernal, C. P. M., Carmona, G. I. O., Peña, L. J. P., & Aponte, C. (2016) · Revista de Salud Pública · doi:10.15446/rsap.v18n6.38871 · Cited by 8
Survival rate among tuberculosis patients identified in south of Iran, 2005-2016
Rahmanian, K., Rahmanian, V., Rahmanian, N., Rastgoofard, M., & Mansoorian, E. (2018) · Journal of Acute Disease · doi:10.4103/2221-6189.244172 · Cited by 8
Co-existence of diabetes and TB among adults in India: a study based on National Family Health Survey data
Sil, A., Patra, D., Dhillon, P., & Narasimhan, P. (2020) · Journal of Biosocial Science · doi:10.1017/s0021932020000516 · Cited by 8
Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima—Peru
Lopez, K., Arriaga, M. B., Aliaga, J., Barreda, N. N., Sanabria, O. M., Huang, C.-C., Zhang, Z., García-de-la-Guarda, R., Lecca, L. W., Carvalho, A. C. C., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0243184 · Cited by 8
Screening of latent tuberculosis infection among patients with diabetes mellitus from a high-burden area in Brazil
Torres, A. V., Corrêa, R. D. S., da Matta, M. D. F. B., do Prado, L. C. F., Bandeira, F. M. G. D. C., Rodrigues, L. S., & Gomes, M. B. (2022) · Frontiers in Clinical Diabetes and Healthcare · doi:10.3389/fcdhc.2022.914574 · Cited by 8
The impact of diabetes mellitus and its control on the development of tuberculosis: a nationwide longitudinal study in Taiwan
Lee, M., Lee, C., Shu, C., Pong, W., Lan, C., Wang, J., Lee, L., & Chao, K. (2013) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3491 · Cited by 8
Diabetes mellitus como factor predictor de tuberculosis en el Servicio de Salud Metropolitano Sur en Santiago, Chile
Paulina Ramonda, C., Paulina Pino, Z., & Valenzuela, L. I. (2012) · Revista chilena de enfermedades respiratorias · doi:10.4067/s0717-73482012000400003 · Cited by 8
Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?
Bosu, W. K. (2014) · Advances in Medical Education and Practice · doi:10.2147/amep.s47412 · Cited by 8
Tuberculosis case burden and treatment outcomes in children, adults and older adults, Vanuatu, 2007–2011
Tagaro, M., Harries, A. D., Kool, B., Ram, S., Viney, K. A., Marais, B. J., & Tarivonda, L. (2014) · Public Health Action · doi:10.5588/pha.13.0074 · Cited by 8
Important co-morbidity in patients with diabetes mellitus in three clinics in Western Kenya
Kirui, N., Pastakia, S. D., Kamano, J. H., Cheng, S. W., Manuthu, E., Chege, P., Gardner, A. F., Mwangi, A., Enarson, D. A., Reid, A. J., et al. (2012) · Public Health Action · doi:10.5588/pha.12.0031 · Cited by 8
Diabetes and Tuberculosis – Old Associates Posing a Renewed Public Health Challenge
Kapur, A., Harries, A. D., Lönnroth, K., Bygbjerg, I. C., Lefèbvre, P., & Senior Advisor, I. U. A. T. A. L. D. (2009) · touchREVIEWS in Endocrinology · doi:10.17925/ee.2009.05.00.10 · Cited by 8
Sputum conversion and treatment success among tuberculosis patients with diabetes treated under the Tuberculosis Control Programme in an Urban setting in South India
Velayutham, B., Bhatnagar, T., Savithri, S., Kumar, N., Kangusamy, B., & Mehendale, S. M. (2017) · Indian Journal of Community Medicine · doi:10.4103/ijcm.ijcm_179_16 · Cited by 8
Effect of human development index on tuberculosis incidence in Asia: An ecological study
Khazaei, Z., Goodarzi, E., Sohrabivafa, M., Dehkordi, A. H., & Moayed, L. (2019) · Advances in Human Biology · doi:10.4103/aihb.aihb_8_19 · Cited by 8
Treatment Delay and Total Delay among Pulmonary Tuberculosis Patients in the North of Iran: Application Survival Data Analysis.
Charati, J. Y., Rezai, M. S., Fendereski, A., Mohammadi, S., & Alipour, N. (2017) · Europe PMC (PubMed Central) · Cited by 8
Bidirectional Screening of Diabetes Mellitus and Tuberculosis in Cambodia
Kheang, S. T., Theang, H., Khun, K. E., Eang, M. T., Kong, S., Loun, C., Olkkonen, A., AlMossawi, H. J., & Kak, N. (2019) · doi:10.35248/2329-891x.19.7.326 · Cited by 8
Infections Associated With Diabetes
Egede, L. E., Hull, B. J., & Williams, J. S. (2018) · Cited by 8
Long-term Protection From Tuberculosis Preventive Treatment Among People With HIV in a High-Burden Tuberculosis Setting: An Observational Cohort Study From India
Agarwal, R., Nyendak, M. R., Chava, N., Allam, R. R., Moonan, P. K., Sriram, C. S., Ganti, R., Ragi, P. K., Polsani, A. R., Yeldandi, V. V., et al. (2025) · Clinical Infectious Diseases · doi:10.1093/cid/ciaf322 · Cited by 7
Adverse pregnancy outcomes and complications of tuberculosis in pregnant women
Su, Y., Kong, X., Chen, Z., Wang, X., & Lu, S. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1550430 · Cited by 7
Integrated Public Health and Health Service Delivery for Noncommunicable Diseases and Comorbid Infectious Diseases and Mental Health
Magee, M. J., Ali, M. K., Prabhakaran, D., Ajay, V. S., & Narayan, K. M. V. (2017) · World Bank, Washington, DC eBooks · doi:10.1596/978-1-4648-0518-9_ch16 · Cited by 7
Diabetes—Tuberculosis Care in Eswatini: A Qualitative Study of Opportunities and Recommendations for Effective Services Integration
Williams, V., Vos, A. G., Haumba, S., Dlamini, L. M., Calnan, M., Grobbee, D. E., Otwombe, K. N., & Klipstein‐Grobusch, K. (2023) · International Journal of Public Health · doi:10.3389/ijph.2023.1605551 · Cited by 7
The effect of diabetes mellitus on tuberculosis in eastern China: A decision‐tree analysis based on a real‐world study
Ling, Y., Chen, X., Zhou, M. R., Zhang, M., Luo, D., Wang, W., Chen, B., & Jiang, J. (2023) · Journal of Diabetes · doi:10.1111/1753-0407.13444 · Cited by 7
Human alveolar macrophage function is impaired in tuberculosis contacts with diabetes
Kleynhans, L., Kunsevi-Kilola, C., Tshivhula, H., Webber, T., Keyser, A. T., Prins, N., Snyders, C., Shabangu, A., Rozot, V., Kidd, M., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.106050 · Cited by 7
HIV prevalence and diabetes prevalence among tuberculosis patients in Antananarivo city: a descriptive study
Rakotonirina, J., Razanakoto, H., Rasolofomanana, L., & Razanakolona, L. R.-S. (2014) · International Journal of Research in Medical Sciences · doi:10.5455/2320-6012.ijrms20140873 · Cited by 7
Diabète chez les nouveaux cas de tuberculose pulmonaire à Hanoï, Vietnam
Thanh, N. P., Khuê, P. M., Sy, D. N., & Strobel, M. (2015) · Bulletin de la Société de pathologie exotique · doi:10.1007/s13149-015-0454-1 · Cited by 7
The diabetes-tuberculosis co-epidemic: the role of international migration
Caraffa, E., Schepisi, M. S., Gualano, G., Parracino, M. P., Rianda, A., Corpolongo, A., Pinnetti, C., Galati, V., Carballo, M., Ippolito, G., et al. (2016) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.15.0295 · Cited by 7
The Intracellular Growth ofM. tuberculosisIs More Associated with High Glucose Levels Than with Impaired Responses of Monocytes from T2D Patients
Torres, M., Herrera, M. T., Miguel, G. F.-S., & González, Y. (2019) · Journal of Immunology Research · doi:10.1155/2019/1462098 · Cited by 7
Prevalence and Clinical Profiling of Dysglycemia and HIV Infection in Persons With Pulmonary Tuberculosis in Brazil
Arriaga, M. B., Araújo‐Pereira, M., Barreto‐Duarte, B., Sales, C., Miguez-Pinto, J. P., Nogueira, E. B., Nogueira, B. M. F., Rocha, M. S., Souza, A. B., Benjamin, A., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2021.804173 · Cited by 7
Type 2 Diabetes Mellitus- and Complication-Related Risk of Nontuberculous Mycobacterial Disease in a South Korean Cohort
Jeon, D. S., Kim, S., Kim, M. A., Chong, Y. P., Shim, T. S., Jung, C. H., Kim, Y., & Jo, K. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04511-22 · Cited by 7
Latent tuberculosis in children and youth with type 1 diabetes mellitus in Dar es Salaam, Tanzania: a cross section survey
Majaliwa, E., Muze, K., Godfrey, E. K., Byashalira, K. C., Mmbaga, B. T., Ramaiya, K. L., & Mfinanga, S. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08753-4 · Cited by 7
Latent tuberculosis diagnostics: current scenario and review
Gupta, A., Chandra, E., Anand, S., Kumar, N. P., Arora, R., Rana, D., & Mrigpuri, P. (2024) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2024.2984 · Cited by 7
A Study on Diabetes Mellitus among Cases of Pulmonary Tuberculosis in a Tertiary Care Hospital, Ahmedabad -
Dutt, N., & Gupta, A. (2014) · National Journal of Medical Research · Cited by 7
A study to assess the blood glucose level among diagnosed cases of tuberculosis registered at a tuberculosis unit of Bhopal city, Madhya Pradesh, India
Nagar, V., Gour, D., Arutagi, V., Dave, L., Bhatia, P., Joshi, A., & Pal, D. K. (2014) · International Journal of Medical Science and Public Health · doi:10.5455/ijmsph.2015.2210201456 · Cited by 7
Clinical characteristics and treatment outcomes among patients with tuberculosis in Bangkok and Nonthaburi, Thailand.
Manosuthi, W., Kawkitinarong, K., Suwanpimolkul, G., Chokbumrungsuk, C., Jirawattanapisal, T., Ruxrungtham, K., & Akksilp, S. (2012) · PubMed · Cited by 7
Notified tuberculosis among Singapore residents by ethnicity, 2002–2011
Lim, L. K.-Y., Enarson, D. A., Reid, A. J. S., Satyanarayana, S., Cutter, J. L., Win, K. M., Chee, C. B.-E., & Wang, Y. T. (2013) · Public Health Action · doi:10.5588/pha.13.0055 · Cited by 7
Screening for Diabetes Mellitus in Patients Diagnosed with Pulmonary Tuberculosis
Pablo-Villamor, M. P., Benedicto, J., Benedicto, J. U., & Perez, V. M. (2014) · Cited by 7
Fatores associados à tuberculose em população de diabéticos: um estudo caso-controle
Leal, M. L., Maciel, E. L. N., & Cadê, N. V. (2019) · Ciência & Saúde Coletiva · doi:10.1590/1413-81232018249.30392017 · Cited by 7
Prevalence of Diabetes among Tuberculosis Patients at Urban Health Centre, Ahmedabad
Mansuri, S., Chaudhari, A., Singh, A., Malek, R., & Viradiya, R. (2015) · Cited by 7
Use of network analysis multidrug‐resistant tuberculosis contact investigation in Kanchanaburi, Thailand
Boonthanapat, N., Soontornmon, K., Pungrassami, P., Sukhasitwanichkul, J., Mahasirimongkol, S., Jiraphongsa, C., Monkongdee, P., Angchokchatchawal, K., & Wiratsudakul, A. (2018) · Tropical Medicine & International Health · doi:10.1111/tmi.13190 · Cited by 7
Factors associated with mortality from tuberculosis in Iran: an application of a generalized estimating equation-based zero-inflated negative binomial model to national registry data
Sarvi, F., Moghimbeigi, A., Mahjub, H., Mahshid, N., & Khodadost, M. (2019) · Epidemiology and Health · doi:10.4178/epih.e2019032 · Cited by 7
Prevalencia de la comorbilidad tuberculosis y diabetes mellitus en Paraguay, 2016 y 2017
Céspedes, C., López, L., Aguirre, S., & Mendoza‐Ticona, A. (2019) · Revista Panamericana de Salud Pública · doi:10.26633/rpsp.2019.105 · Cited by 7
A public-private model to scale up diabetes mellitus screening among people accessing tuberculosis diagnostics in Dhaka, Bangladesh
Paul, K. K., Alkabab, Y., Rahman, M. M., Ahmed, S., Amin, M. J., Hossain, M. D., Heysell, S. K., & Banu, S. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.01.001 · Cited by 7
Mycobacterial Growth Inhibition Assay (MGIA) as a Host Directed Diagnostic Tool for the Evaluation of the Immune Response in Subjects Living With Type 2 Diabetes Mellitus
Bobadilla-del-Valle, M., Leal-Vega, F. J., Torres‐González, P., Ordaz‐Vázquez, A., García‐García, L., Tovar-Vargas, M. D. L. A., Delgado-Sánchez, G., Guerra-de-Blas, P. D. C., Wallis, R. S., Ponce‐de‐León, A., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.640707 · Cited by 7
Pulmonary Complications of Endocrine Diseases
Zimmerman, L. H. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-3383-5.00095-6 · Cited by 7
Mycobacteria
Simner, P. J., Woods, G. L., & Wengenack, N. L. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.dmih2-0016-2015 · Cited by 7
Survival of Cuban Patients with Pulmonary Tuberculosis (2009–2010)
Martínez-Rodríguez, A., González-Díaz, A., Armas-Pérez, L., Sánchez-Valdés, L., Martínez-Morales, M. A., & González-Ochoa, E. R. (2016) · MEDICC Review · doi:10.37757/mr2016.v18.n1-2.5 · Cited by 7
Influence of diabetes mellitus and risk factors in activating latent tuberculosis infection: a case for targeted screening in malaysia.
Swarna Nantha, Y. (2012) · PubMed · Cited by 7
Diabetes in Asia
Sharma, V., & Kumar, V. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60435-7 · Cited by 7
Where can Tanzania health system integrate clinical management of patients with dual tuberculosis and diabetes mellitus? A cross-sectional survey at varying levels of health facilities
Chamba, N. G., Byashalira, K. C., Shayo, P. J., Ramaiya, K. L., Manongi, R. N., Daud, P., Mmbaga, B. T., Ntinginya, N. E., Lillebæk, T., Bygbjerg, I. C., et al. (2022) · Public Health in Practice · doi:10.1016/j.puhip.2022.100242 · Cited by 6
Large language models and large concept models in radiology: Present challenges, future directions, and critical perspectives
Merchant, S. A., Merchant, N., Varghese, S. L., & Shaikh, M. J. S. (2025) · World Journal of Radiology · doi:10.4329/wjr.v17.i11.114754 · Cited by 6
The yield of chest X-ray based versus symptom-based screening among patients with diabetes mellitus in public health facilities in Addis Ababa, Ethiopia
Jerene, D., Muleta, C., Dressie, S., Ahmed, A., Tarekegn, G., Haile, T., Bedru, A., Mustapha, G., Gebhard, A. C., & Wares, F. (2022) · Journal of Clinical Tuberculosis and Other Mycobacterial Diseases · doi:10.1016/j.jctube.2022.100333 · Cited by 6
Diabetes as a risk factor for tuberculosis disease
Franco, J. V. A., Metzendorf, M., Risso, A., Boeckmann, M., Schlesinger, S., Damen, J. A., Richter, B., Baddeley, A., Carlqvist, A., Bastard, M., et al. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd016013 · Cited by 6
Prevalence and Associated Factors of Diabetes Mellitus Among Newly Enrolled Tuberculosis Patients in Lubumbashi (DRC)
Kakisingi, C. N., Mwamba, C., Muteba, M. K., Éric, K. I., Nzaji, M. K., Tanon, A., & Situakibanza, H. N.-T. (2024) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s436873 · Cited by 6
The double burden: a new-age pandemic meets an ancient infection
Bridson, T. L., Govan, B. L., Norton, R. E., Schofield, L., & Ketheesan, N. (2014) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/tru135 · Cited by 6
Using Spatial Disease Patterns and Patient‐Level Characteristics to Describe Prevalence Elastic Behavior in Treatment for Latent Tuberculosis Infection ( LTBI )
Fluegge, K. (2015) · Public Health Nursing · doi:10.1111/phn.12170 · Cited by 6
Perfil clínico y social de pacientes con tuberculosis en una unidad de medicina familiar de Reynosa, Tamaulipas, México
Hernández-Guerrero, I. A., Vázquez-Martínez, V. H., Guzmán-López, F., Ochoa-Jiménez, L. G., & Cervantes-Vázquez, D. A. (2015) · Atención Familiar · doi:10.1016/s1405-8871(16)30070-0 · Cited by 6
Is there a connection between gestational diabetes mellitus, human immunodeficiency virus infection, and tuberculosis?
Alexander, M., Gupta, A., & Mathad, J. S. (2019) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.18.0337 · Cited by 6
Testing for Mycobacterium tuberculosis infection using the QuantiFERON-TB GOLD assay in patients with comorbid conditions in a tertiary care endemic setting
Masood, K. I., Jamil, B., Akber, A., Hassan, M., Islam, M., & Hasan, Z. (2020) · Tropical Diseases Travel Medicine and Vaccines · doi:10.1186/s40794-020-0102-z · Cited by 6
The Impact of Diabetes and Prediabetes on Prevalence of Mycobacterium tuberculosis Infection Among Household Contacts of Active Tuberculosis Cases in Ethiopia
Smith, A., Kempker, R. R., Wassie, L., Bobosha, K., Nizam, A., Gandhi, N. R., Auld, S. C., Magee, M. J., Blumberg, H. M., Ernst, J., et al. (2022) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofac323 · Cited by 6
The Association of Gestational Diabetes with HIV Infection and Tuberculosis in Indian Women
Chebrolu, P., Alexander, M., Bhosale, R. A., Naik, S., Gupte, N., Lee, M. H., Kumar, P., Babu, S., Fitzgerald, D. W., Gupta, A., et al. (2022) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.21-1106 · Cited by 7
Sleep disorders in elderly population suffering from TB and respiratory diseases
Devassy, T. V., Nishanth, P. S., Sharma, D., & Thomas, A. M. (2022) · Indian Journal of Tuberculosis · doi:10.1016/j.ijtb.2022.10.019 · Cited by 6
Epidemiological cluster identification using multiple data sources: an approach using logistic regression
Susvitasari, K., Tupper, P. F., Cancino‐Muñoz, I., López, M. G., Comas, I., & Colijn, C. (2023) · Microbial Genomics · doi:10.1099/mgen.0.000929 · Cited by 6
Innovative Integrated Motivational Interviewing for Dual Management in Tuberculosis Patients with Diabetes (MID-DOT) in Malaysia
Mohammad, W. M. Z. W., Ahmad, S. R., Yaacob, N. A., Shariff, N. M., Jaeb, M. Z. M., & Hussin, Z. (2023) · Healthcare · doi:10.3390/healthcare11131929 · Cited by 6

Authors: Jeon, C. Y., & Murray, M. B.
Affiliations: Harvard University (US)
Corresponding author: Jeon, Christie Y
ORCID: Jeon, Christie Y
Murray, Megan B
Venue: PLoS Medicine
Publisher: Public Library of Science (PLoS)
Published: 2008-07-15
Volume: 5
Issue: 7
Pages: e152
ISSN: 1549-1277 (ISSN-L)
1549-1676
DOI: 10.1371/journal.pmed.0050152
PMC: PMC2459204
OpenAlex: W2104101804
Cited by: 1,486
References: 47
Citations by year: 2026: 51 · 2025: 68 · 2024: 83 · 2023: 87 · 2022: 104 · 2021: 102 · 2020: 100 · 2019: 122 · 2018: 114 · 2017: 116 · 2016: 114 · 2015: 91 · 2014: 87 · 2013: 75 · 2012: 66
FWCI: 4.02
Type: journal article
Language: en
Update notices: correction (2008-08-26)
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (unspecified)
Locations: PLoS Medicine (publishedVersion, cc-by)
PubMed Central (publishedVersion, other-oa)
PubMed (publishedVersion)
Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
RePEc: Research Papers in Economics (submittedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Figshare (submittedVersion, cc-by)
Topics: Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
Health Sciences › Medicine › Infectious Diseases › Diagnosis and treatment of tuberculosis
Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
Keywords: diabetes mellitus, active tuberculosis, tuberculosis risk, comorbidities, tuberculosis control, latent tuberculosis infection, active case finding
MeSH terms: Diabetes Mellitus, Type 2, Humans, Risk Factors, Tuberculosis, Diabetes Complications

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks