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Cited by 48Insect Resistance and GeneticsMosquito-borne diseases and controlDengue and Mosquito Control Research

Pyrethroid resistance alters the blood-feeding behavior in Puerto Rican Aedes aegypti mosquitoes exposed to treated fabric

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Agramonte, Natasha M., Bloomquist, Jeffrey R., Bernier, Ulrich R.·2017·PLOS Neglected Tropical Diseases
DOI 10.1371/journal.pntd.0005954PMC PMC5624645
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Abstract

Emerging insecticide resistance is a major issue for vector control. It decreases the effectiveness of insecticides, thereby requiring greater quantities for comparable control with a net increase in risk of disease resurgence, product cost, and damage risk to the ecosystem. Pyrethroid resistance has been documented in Puerto Rican populations of Aedes aegypti (L.) mosquitoes. In this study, topical toxicity of five insecticides (permethrin, etofenprox, deltamethrin, DDT, transfluthrin) was determined for susceptible (Orlando-ORL) and resistant (Puerto Rico-PR) strains of Ae. aegypti. Resistance ratios were calculated using LD50 values, and high resistance ratios for permethrin (112) and etofenprox (228) were observed for the Puerto Rico strain. Behavioral differences in blood-feeding activity for pyrethroid-resistant and pyrethroid-susceptible strains of Ae. aegypti when exposed to pyrethroid-treated cloth were also explored. Strains were exposed for 15 min to a range of concentrations of pyrethroid-treated uniform fabric in a cage that contained 60 female Ae. aegypti mosquitoes. Interestingly, the resistance ratios for blood-feeding were similar for permethrin (61) and etofenprox (70), but were lower than their respective resistance ratios for topical toxicity, suggesting that knockdown resistance was the primary mechanism of resistance in the blood feeding assays. Results showed a rightward shift in the dose-response curves for blood-feeding that indicated higher concentrations of pyrethroids were necessary to deter blood-feeding behavior in the pyrethroid-resistant Puerto Rican strain of Ae. aegypti.

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Authors
Agramonte, N. M., Bloomquist, J. R., & Bernier, U. R.
Affiliations
  • Agricultural Research Service (US)
  • University of Florida (US)
Corresponding author
Agramonte, Natasha M.
ORCID
Venue
PLOS Neglected Tropical Diseases
Publisher
Public Library of Science (PLoS)
Published
2017-09-20
Volume
11
Issue
9
Pages
e0005954
ISSN
  • 1935-2727 (ISSN-L)
  • 1935-2735
DOI
10.1371/journal.pntd.0005954
PMC
PMC5624645
OpenAlex
W2756322811
Cited by
48
References
4
Citations by year
2026: 1 · 2025: 6 · 2024: 3 · 2023: 5 · 2022: 6 · 2021: 6 · 2020: 5 · 2019: 6 · 2018: 10
FWCI
2.35
Type
journal article
Language
en
Update notices
new_version (2017-10-02)
Open access
Licence
Locations
  • PLoS neglected tropical diseases (publishedVersion, public-domain)
  • Europe PMC (PubMed Central) (publishedVersion, public-domain)
  • PubMed Central (publishedVersion, public-domain)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Figshare (submittedVersion, cc-by)
Funders
  • U.S. Department of Defense
  • Agricultural Research Service (58-6615-4-023)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Insect Resistance and Genetics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Mosquito-borne diseases and control
  • Social Sciences › Sociology and Political Science › Dengue and Mosquito Control Research
Keywords
pyrethroid resistance, Aedes aegypti, blood-feeding behavior, permethrin, etofenprox, deltamethrin, transfluthrin, DDT, knockdown resistance, vector control, resistance ratio
MeSH terms
Aedes, Animals, Feeding Behavior, Female, Insecticide Resistance, Insecticides, Puerto Rico, Pyrethrins, Textiles

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