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Henipavirus RNA in African Bats
Open accessAbstract
BACKGROUND: Henipaviruses (Hendra and Nipah virus) are highly pathogenic members of the family Paramyxoviridae. Fruit-eating bats of the Pteropus genus have been suggested as their natural reservoir. Human Henipavirus infections have been reported in a region extending from Australia via Malaysia into Bangladesh, compatible with the geographic range of Pteropus. These bats do not occur in continental Africa, but a whole range of other fruit bats is encountered. One of the most abundant is Eidolon helvum, the African Straw-coloured fruit bat. METHODOLOGY/PRINCIPAL FINDINGS: Feces from E. helvum roosting in an urban setting in Kumasi/Ghana were tested for Henipavirus RNA. Sequences of three novel viruses in phylogenetic relationship to known Henipaviruses were detected. Virus RNA concentrations in feces were low. CONCLUSIONS/SIGNIFICANCE: The finding of novel putative Henipaviruses outside Australia and Asia contributes a significant extension of the region of potential endemicity of one of the most pathogenic virus genera known in humans.
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Drexler, J. F., Corman, V. M., Müller, M. A., Maganga, G. D., Vallo, P., Binger, T., Gloza-Rausch, F., Cottontail, V. M., Rasche, A., Yordanov, S., et al. (2012) · Nature Communications · doi:10.1038/ncomms1796 · Cited by 686
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Cedar Virus: A Novel Henipavirus Isolated from Australian Bats
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Metadata
- Authors
- Drexler, J. F., Corman, V. M., Gloza-Rausch, F., Seebens, A., Annan, A., Ipsen, A., Kruppa, T., Müller, M. A., Kalko, E. K. V., Adu-Sarkodie, Y., Oppong, S., & Drosten, C.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2009-07-28
- Volume
- 4
- Issue
- 7
- Pages
- e6367
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W2022077785
- Cited by
- 223
- References
- 0
- FWCI
- 10.28
- Type
- journal article
- Language
- en
- Open access
- gold
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- Drexler, J. F., Corman, V. M., Gloza-Rausch, F., Seebens, A., Annan, A., Ipsen, A., Kruppa, T., Müller, M. A., Kalko, E. K. V., Adu-Sarkodie, Y., Oppong, S., & Drosten, C. (2009). Henipavirus RNA in African Bats. PLoS ONE. https://doi.org/10.1371/journal.pone.0006367
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