The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

Darash-Yahana, Merav, Gillespie, John W., Hewitt, Stephen M., Chen, Yun-Yun K., Maeda, Shin, Stein, Ilan, Singh, Satya P., Bedolla, Roble B. +5 more·2009·PLoS ONE
DOI 10.1371/journal.pone.0006695

Cited by (143)

Items 101–143 of 143

  1. The Role of Chemokines in Migration of Metastatic-like Lymphangioleiomyomatosis Cells
    Gustavo Pacheco–Rodriguez, Joel Moss · 2010 · Critical Reviews in Immunology
  2. Integrative characterisation of secreted factors involved in intercellular communication between prostate epithelial or cancer cells and fibroblasts
    Yunjian Wu, Kimberley C. Clark, Birunthi Niranjan, Anderly C. Chüeh, Lisa Glen Horvath, Renea A. Taylor, Roger J. Daly · 2023 · Molecular Oncology
  3. High expression of CXC chemokine receptor 6 associates with poor prognosis in patients with clear cell renal cell carcinoma
    Yuan Chang, Lin Zhou, Le Xu, Qiang Fu, Yuanfeng Yang, Zongming Lin, Jiejie Xu · 2017 · Urologic Oncology Seminars and Original Investigations
  4. Chemokines key players in cancer progression and metastasis
    Shailesh Singh · 2011 · Frontiers in Bioscience-Scholar
  5. Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers
    Houtan Noushmehr, T Sabedot, TM Malta, K Nelson, J Snyder, M Wells, Ana C. deCarvalho, Abir Mukherjee, Dhananjay Arun Chitale, Maritza S. Mosella et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  6. Increased plasma sCXCL16 levels may have a relationship with Th1/Th2 imbalance in primary immune thrombocytopenia
    Yating Hao, Yang Li, Huiyuan Li, Mingen Lyu, Donglei Zhang, Rongfeng Fu, Yue Guan, Shixuan Wang, Boyang Sun, Xueqing Dou et al. · 2017 · Cytokine
  7. A distinct population of CD8+ T cells expressing CD39 and CD73 accumulates with age and supports cancer progression
    Monica Bodogai, Bong Soo Park, Fatima-Zohra Braikia, Fnu Naqing, Konda Kumaraswami, Chen Chen, Emeline Ragonnaud, Sharon M. Stack, Steffen Ormanns, Michael Guenther et al. · 2025 · Nature Aging
  8. CXC chemokine ligand 16, inversely correlated with CD99 expression in Hodgkin Reed-Sternberg cells, is widely expressed in diverse types of lymphomas
    Fang Liu, Yu Zhang, Hongping Tang, Xinhua Zhou, Ziqing Wu, Dongsheng Tang, Tong Zhao · 2013 · Oncology Reports
  9. Associations of CXCL16, miR‑146a and miR‑146b in atherosclerotic apolipoprotein E‑knockout mice
    Aijun Ma, Xiaoyan Zhu, Shaonan Yang, Xudong Pan, Ting Wang, Yuan Wang, Xing Xiao, Shihai Liu · 2018 · Molecular Medicine Reports
  10. Pathogenesis of Germinal Matrix Hemorrhage: Insights from Single-Cell Transcriptomics
    Jiapei Chen, Jennifer Ja-Yoon Choi, Pin-Yeh Lin, Eric Jinsheng Huang · 2024 · Annual Review of Pathology Mechanisms of Disease
  11. Cross-Talk of Breast Cancer Cells with the Immune System
    Sandra Demaria, A. Karsten, Sylvia Adams · 2011 · InTech eBooks
  12. Genetically Engineered Mesenchymal Stem Cells
    Khalid Shah · 2014 · Elsevier eBooks
  13. Methylation Signature Genes Identification of the Lung Squamous Cell Carcinoma Occurrence and Recognition Research
    Xuedong Wang, Wenhui Shang, Yu Chang, Xiaoqin Li · 2018 · Journal of Computational Biology
  14. Migration, Metastasis, and More: The Role of Chemokines in the Proliferation, Spreading, and Metastasis of Tumors
    Rolf Mentlein, Kirsten Hattermann, Janka Held‐Feindt · 2013 · Springer eBooks
  15. Role of Chemokines and Chemokine Receptors in Cancer
    Pierre-Louis Loyher, Mathieu Paul Rodero, Christophe Combadière, Alexandre Boissonnas · 2020 · Springer eBooks
  16. Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy
    Imran Siddiqui, Alberto Mantovani, Paola Allavena · 2014 · Springer eBooks
  17. NR4A3high mast cells promote ovarian cancer metastasis by reprogramming tumor-associated macrophages via JAK2/STAT6 signaling
    Xiaofeng Bian, Yi‐Rong Chen, Caixia Zhang, Shijia Huang, Xiaorui Fu, Bowen Yang, Siyan Lu, Wei Zhao, Yan Pan, Shuli Zhao · 2025 · Translational Oncology
  18. Targeting CXCR6 Disrupts β-Catenin Signaling and Enhances Sorafenib Response in Hepatocellular Carcinoma
    Morgan E. Reeves, Anastasia Chambers, Abhishek P Shrestha, Sergio Duarte, Ali Zarrinpar, Siobhan Malany, Satyamaheshwar Peddibhotla · 2025 · Cancers
  19. Network and Gene Set Enrichment Analysis of Adipokine Drivers of Prostate Cancer; Unravelling the Mechanistic Link Between Excess Adiposity and Prostate Cancer Risk
    Zachary S. Dovey, Elena Tomás Bort, Jeffrey Ian Mechanick · 2025 · Cancer Medicine
  20. Fibroblasts Derived From Vestibular Schwannoma Express Protumorogenic Markers
    Paramita Baruah, Jennifer L. Marshall, Philip N. Jones, Triin Major, Valentina Pucino, John D. O’Neil, Meriam Nefla, Helen Michelle McGettrick, Peter Monksfield, Richard M Irving et al. · 2023 · Otology & Neurotology
  21. Diagnostic significance of a color Doppler ultrasound combined with serum CXCL16 and E-cad in cervical cancer
    Wenrong Wang, Xing Gao, Yuan Zhu, Yaozhi Qi, Yanjuan Wang · 2021 · Translational Cancer Research
  22. Inhibition of selective factor Xa suppresses type 1 diabetes development in mice via the CXCL16 chemokine
    Mohamed Sadek Abdel‐Bakky, Hamdoon Abdelhamid Mohammed, Elham Amin · 2024 · Pharmacia
  23. Inflammatory Microenvironment in Prostate Carcinogenesis
    Geraldine Gueron, Javier Cotignola, Elba Susana Vazquez · 2013 · InTech eBooks
  24. Role of Chemokines and Chemokine Receptors in Cancer
    Mathieu Paul Rodero, Christophe Combadière, Alexandre Boissonnas · 2014 · Springer eBooks
  25. Investigating novel biomarkers in uterine corpus endometrial carcinoma: in silico analysis and clinical specimens validation via RT-qPCR and immunohistochemistry.
    Jie Li, Faiqah Ramzan, Guiping Zhong · 2023 · PubMed Central
  26. CXCR6+ T cells promote apoptosis and necroptosis in proximal tubules during AKI-to-CKD transition
    Xiaoxu Li, Isabel Melchinger, Yuchu Chen, Guo Jiankan, Lloyd G. Cantley, Leyuan Xu · 2026 · Cell Death and Disease
  27. Advancements in understanding and treating CXCL16/CXCR6 in tumors and in inflammatory diseases: a narrative review
    Xiaohong Li, S J Liu, Die Qian, Maokui Huang, Mingmin Na, Qingyan Mo, Mingqian Ju, Jingjing Ge, Jie Gao, Xueling Zhang et al. · 2026 · Frontiers in Immunology
  28. Prognostic Implications of the Expression of CXCL16 in Breast Carcinoma
    Dong-Youl Choi, Ran Hong, Sung-Churl Lim, Keun-Hong Kee, Chae‐Hong Suh, Mi‐Ja Lee · 2011 · Journal of Pathology and Translational Medicine
  29. CXCL16 mediates nociception and inflammation in murine post-traumatic osteoarthritis
    Lindsey Lammlin, Stephen J. Redding, Alexander J. Knights, Aanya Mohan, Michael D. Newton, Rachel F. Bergman, Isabelle J. Smith, Scarlet C. Howser, Sofia Gonzalez-Nolde, Phillip Rzeczycki et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Tumor Immunotherapy by Utilizing a Double-Edged Sword, Chemokines
    Naofumi Mukaida, Soichiro Sasaki, Tomohisa Baba · 2013 · Springer eBooks
  31. Cell-Cell Fusion, Chemotaxis and Metastasis
    George E. Parris · 2015 · Springer eBooks
  32. THE ROLES OF CHEMOKINES, CHEMOKINE RECEPTORS AND GLYCOLIPID ACTIVATION IN NKT CELL TUMOUR INFILTRATION
    Natasa Zatezalo · 2017 · DalSpace (Dalhousie University)
  33. The Functional Characterization of Invariant Natural Killer T Cells and the Chemokine Receptor CXCR6 in a Mouse Model of Inflammatory Arthritis
    Drew Slauenwhite · 2017 · DalSpace (Dalhousie University)
  34. Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T-Cells in Cancer Immunotherapy
    Imran Siddiqui, Debora Vignali, Marinos Kallikourdis, Alberto Mantovani, Paola Allavena · 2020 · Springer eBooks
  35. CXC Chemokine Ligand 16 Promotes the Proliferation and Migration of Hodgkin and Reed-Sternberg Cells Via the PI3K/Akt/NF-κB Signaling Pathway
    Yang Xun, Dinghua Shen, Hua Yang, Yijun Liang, Ruixue Wang, Lixia Fan, Hui Liu, Yilong Ai, Dahai Liu, Fang Liu et al. · 2021 · Novel Approaches in Cancer Study
  36. Chemokines and Chemokine Receptors in Cancer: An Update
    Noha Mousaad Elemam, Azzam A. Maghazachi · 2023 · Springer eBooks
  37. Integrated multiplex network based approach reveled CC and CXC chemokines associated key biomarkers in colon adenocarcinoma patients.
    Wei Hsuan Huang, Yanyan Hu, Xiaotao Zhang, Yan Xu, Zhiling Sun, Ping’an Ding, Xiaoping Qian, Akbar Ali, Zilu Chen · 2023 · PubMed Central
  38. Establishment of fracture blister model and analysis of plasma protein markers in rats
    Xin Hu, Peiyuan Wang, Tao Wang, Jingcheng Cao, Kezheng Du, Marius M. Scarlat, Lin Liu, Yutong Li, Xin Wang, Haofei Wang et al. · 2025 · Frontiers in Immunology
  39. Chemokines and Chemokine Receptors in Cancer: An Update
    Noha Mousaad Elemam, Azzam A. Maghazachi · 2025 · Springer eBooks
  40. Additional file 1 of Role of CXCL16 in BLM-induced epithelial–mesenchymal transition in human A549 cells
    Ma, Zhenzhen, Ma, Chunyan, Zhang, Qingfeng, Bai, Yang, Kun Mu, Liu, Xiangyuan, Yang, Qingrui · 2021 · Figshare
  41. Translatome-based classification of pancreatic cancer
    Sauyeun Shin · 2020
  42. CXCL16 gene promoter methylation is associated with inflammation in patients with chronic hepatitis B
    Zhezhe Tian, Miaomiao Xu, Hongfei Li, Yunxin Yao, Yuchen Fan, Shuai Gao, Kai Wang · 2026 · Virology Journal
  43. Diagnostic Potential of Circulating CXCL13, CXCL14, and CXCL16 in Colorectal Cancer: A Preliminary Case–Control Study
    Adrianna Romanowicz, Marta Łukaszewicz‐Zając, Agnieszka Kulczyńska‐Przybik, Kamil Safiejko, Marcin Juchimiuk, Barbara Mroczko · 2026 · Cancers