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Mitochondrial Haplogroup H1 in North Africa: An Early Holocene Arrival from Iberia

Ottoni, Claudio, Primativo, Giuseppina, Hooshiar Kashani, Baharak, Achilli, Alessandro, Martínez-Labarga, Cristina, Biondi, Gianfranco, Torroni, Antonio, Rickards, Olga·2010·PLoS ONE
DOI 10.1371/journal.pone.0013378PMC PMC2958834
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Figure 1 Most parsimonious tree of complete H1 mtDNA sequences from North Africa. The tree includes 18 complete mtDNA sequences and illustrates sub-haplogroup affiliations, including the novel sub-haplogroups H1v, H1w and H1x. Eleven sequences are from the Tuareg of Libya and seven were previously published: four Tunisians, two Moroccan Jews, and one Berber from Egypt (Table S1 and the supplementary References S1). The position of the revised Cambridge reference sequence (rCRS) [47] is indicated for reading off sequence motifs. Tuareg mtDNAs were selected through a preliminary sequence analysis of the control region and an RFLP survey in order to include the widest possible range of internal variation of haplogroup H1. The sequencing procedure and phylogeny construction were performed as described elsewhere [17], [30]. Mutations are shown on the branches; they are transitions unless a base is explicitly indicated. The prefix @ designates reversions, while suffixes indicate: transversions (to A, G, C, or T), indels (+, d), gene locus (∼t, tRNA; ∼r, rRNA; ∼nc, non coding region outside of the mtDNA control region), and synonymous or non-synonymous changes (s or ns). Recurrent mutations are underlined. The root of H1o has been defined according to Behar et al. [36]. Additional information regarding each mtDNA is available on Table S1 and on the supplementary References S1. MtDNAs # 1 and 2 are from Moroccan Jews [36], # 3–7 and 9–14 are from Libyan Tuareg, # 8 and 15–17 are from Tunisian subjects [35], and # 18 is from a Berber of Egypt [17].
Figure 1 Most parsimonious tree of complete H1 mtDNA sequences from North Africa. The tree includes 18 complete mtDNA sequences and illustrates sub-haplogroup affiliations, including the novel sub-haplogroups H1v, H1w and H1x. Eleven sequences are from the Tuareg of Libya and seven were previously published: four Tunisians, two Moroccan Jews, and one Berber from Egypt (Table S1 and the supplementary References S1). The position of the revised Cambridge reference sequence (rCRS) [47] is indicated for reading off sequence motifs. Tuareg mtDNAs were selected through a preliminary sequence analysis of the control region and an RFLP survey in order to include the widest possible range of internal variation of haplogroup H1. The sequencing procedure and phylogeny construction were performed as described elsewhere [17], [30]. Mutations are shown on the branches; they are transitions unless a base is explicitly indicated. The prefix @ designates reversions, while suffixes indicate: transversions (to A, G, C, or T), indels (+, d), gene locus (∼t, tRNA; ∼r, rRNA; ∼nc, non coding region outside of the mtDNA control region), and synonymous or non-synonymous changes (s or ns). Recurrent mutations are underlined. The root of H1o has been defined according to Behar et al. [36]. Additional information regarding each mtDNA is available on Table S1 and on the supplementary References S1. MtDNAs # 1 and 2 are from Moroccan Jews [36], # 3–7 and 9–14 are from Libyan Tuareg, # 8 and 15–17 are from Tunisian subjects [35], and # 18 is from a Berber of Egypt [17].CC BY · PubMed Central
Figure 2 Spatial frequency distribution (%) of haplogroup H1 in western Eurasia and North Africa. The inset illustrates the geographic location of populations surveyed. Populations and corresponding frequency values are listed in Table S3 and in the supplementary References S1.
Figure 2 Spatial frequency distribution (%) of haplogroup H1 in western Eurasia and North Africa. The inset illustrates the geographic location of populations surveyed. Populations and corresponding frequency values are listed in Table S3 and in the supplementary References S1.CC BY · PubMed Central
Figure 3 Spatial frequency distribution (%) of haplogroup H1 in western Eurasia and North Africa after excluding the Libyan Tuareg samples.
Figure 3 Spatial frequency distribution (%) of haplogroup H1 in western Eurasia and North Africa after excluding the Libyan Tuareg samples.CC BY · PubMed Central

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Cited by

Metadata

Authors
Ottoni, C., Primativo, G., Hooshiar Kashani, B., Achilli, A., Martínez-Labarga, C., Biondi, G., Torroni, A., & Rickards, O.
Venue
PLoS ONE
Publisher
Public Library of Science (PLoS)
Published
2010-10-21
Volume
5
Issue
10
Pages
e13378
ISSN
1932-6203
DOI
10.1371/journal.pone.0013378
PMC
PMC2958834
Cited by
49
References
0
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

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