2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease
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- Markers of Alzheimer’s Disease in Primary Visual Cortex in Normal Aging in MiceLuis Fernando Hernández-Zimbrón, M Pérez-Hernández, Abigail Torres-Romero, Elisa Gorostieta-Salas, Roberto González-Salinas, Rosario Gulías-Cañizo, Hugo Quiroz–Mercado, Edgar Zenteno · 2017 · BioMed Research International
- Ketogenic Approaches for the Treatment of Alzheimer’s DiseaseRenata Gabuzyan, Christopher Lee, H. Nygaard · 2024 · Journal of Alzheimer's Disease
- Metabolic Management of CancerThomas N. Seyfried · 2012 · Wiley eBooks
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- Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer’s diseasePaule E. H. M’Bra, Laura K. Hamilton, Gaël Moquin‐Beaudry, Chenicka Lyn Mangahas, Federico Pratesi, Anne Castonguay, Sophia Mailloux, Manon Galoppin, Jessica Avila Lopez, Megan Bernier et al. · 2025 · Brain
- 2-Deoxyglucose protects hippocampal neurons against kainate-induced temporal lobe epilepsy by modulating monocyte-derived macrophages (mo-MΦ) and progranulin production in the hippocampusFarnaz Nikbakht, Rafie Belali, Homa Rasoolijazi, Ali Mohammadkhanizadeh · 2019 · Neuropeptides
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- A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activityAbbi R. Hernandez, Maya E. Barrett, Katelyn N. Lubke, A. P. Maurer, S. Burke · 2023 · Frontiers in Aging Neuroscience
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- Chronic Dietary Administration of 2-Deoxy-D-Glucose Does Not Compromise Neurobehavioral Functions at Tumor Preventive Doses in MiceSaurabh Pratap Singh, Mayank Kumar, Kailash Manda, Seenu Haridas, Anant Narayan Bhatt, Daman Saluja, Bilikere Srinivasa Rao Dwarakanath · 2015 · Journal of Behavioral and Brain Science
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- Endogenous drivers of altered immune cell metabolismLianne C. Shanley, Hannah K. Fitzgerald, Sinead A O’Rourke, Aisling Dunne · 2022 · Experimental Biology and Medicine
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- Mitochondrial Function and Neurodegenerative DiseasesWilkins, Heather M., Weidling, Ian, Koppel, Scott, Wang, Xiaowan, von Schulze, Alex, Swerdlow, Russell H. · 2018 · The Molecular and Cellular Basis of Neurodegenerative Diseases
- A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activityAbbi R. Hernandez, Maya E. Barrett, Katelyn N. Lubke, A. P. Maurer, S. Burke · 2023 · bioRxiv
- Targeting Mitochondria and Redox Dyshomeostasis in Brain Ageing: An UpdateSusana Cardoso, Paula Isabel Moreira · 2021 · Healthy ageing and longevity
- A machine learning-based holistic approach for the diagnosis of patients suffering from different conditions within the Alzheimer's disease spectrumN. Massetti, Alberto Granzotto, M. Bomba, S. Pizzi, A. Mosca, Reinhold Scherer, M. Onofrj, S. Sensi · 2020 · medRxiv
- Lifestyle Factors, Mitochondrial Dynamics, and NeuroprotectionKatheryn Broman, Abigail U. Davis, Jordan May, Hana Park · 2019 · IntechOpen eBooks
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- Suppression of the dihydrolipoamide dehydrogenase gene ( dld-1 ) protects against the toxicity of human amyloid beta in C. elegans model of Alzheimer’s diseaseWaqar Ahmad · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy miceAnn Wells, John J. Wilson, Sarah E. Heuer, John D. Sears, Jian Ning Wei, Raghav Pandey, Mauro W. Costa, Catherine Cook Kaczorowski, Derry C. Roopenian, Chih‐Hao Chang et al. · 2024 · PLoS ONE
- Metabolic shift toward ketosis in asocial cavefish increases social-like affinityMotoko Iwashita, Amity Tran, Marianne Garcia, Jia Cashon, Devanne Burbano, Vanessa dos Santos Chiappetta Nogue Salgado, Malia Hasegawa, Rhoada Balmilero-Unciano, Kaylah Politan, Miki Wong et al. · 2023 · BMC Biology
- Modulatory role of ketogenic diet on neuroinflammation; a possible drug naïve strategy to treatment of Parkinson’s diseaseS. Shaafi, J. Mahmoudi, S. Najmi, S. Sadigh-Eteghad, M. Farhoudi, H. Aliasgharpour · 2015
- Targeting Alzheimer's disease neuronal mitochondria as a therapeutic approachIsaac G. Onyango, Gorazd Bernard Stokin · 2020 · Elsevier eBooks
- Alzheimer’s disease, epigenetics, and exerciseStuart M. Raleigh, Tom Cullen · 2021 · Elsevier eBooks
- Roles of glycolytic and pyruvate metabolism enzymes in Alzheimer’s disease glycometabolic reprogramming and their therapeutic potentialMinmin Chen, Changmin Zuo, Runzhi Li, Jinlong Zhang, Zeshan Yao, Liping Li, Li Cheng · 2026 · Discover Neuroscience
- Microglial immunometabolism in Alzheimer's disease: A stage-resolved trajectory from adaptive remodeling to the metabolic paradoxYue Zou, Yi Ou, Hang Zhao, Ge Chen, Zhong Chen, Yunqin Li, Junliang Jiang · 2026 · Biomedicine & Pharmacotherapy
- Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathiesYuanyuan Yong, Yu-Xin Hu, Qian Feng, Xiao-Gang Zhou, Lu Yu, Da-Lian Qin, Jia-Ning Mi, Jian-Ming Wu, Jian-Xin Liu, An-Guo Wu · 2026 · International Journal of Molecular Medicine
- Dietary Impact on Neuronal Autophagy Control and Brain HealthClaudia Ntsapi, André du Toit, Ben Loos · 2019 · IntechOpen eBooks
- Glucose facilitates Aβ oligomerization and tau phosphorylation in C. elegans model of Alzheimer’s diseaseWaqar Ahmad · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Metabolic study of Alzheimer’s disease using mutant C. elegansWaqar Ahmad · 2017 · The University of Queensland
- Ketogenic Diets for the Treatment of Neurologic DiseaseChrista Whelan Habela, Eric Heath Kossoff · 2015 · Wiley eBooks
- Magnetic Resonance Spectroscopy of Metabolic Changes in the Brains of Mice Given 2-Deoxy-D-Glucose and LipopolysaccharideM. Moshkin, A. Akulov, D. Petrovskii, O. Saik, E. D. Petrovskii, A. Savelov, I. Koptyug · 2014 · Neuroscience and Behavioral Physiology
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