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The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn’s disease

Glas, Jürgen, Seiderer, Julia, Bayrle, Corinna, Wetzke, Martin, Fries, Christoph, Tillack, Cornelia, Olszak, Torsten, Beigel, Florian, Steib, Christian, Friedrich, Matthias, Diegelmann, Julia, Czamara, Darina, Brand, Stephan·2011·PLoS ONE
DOI 10.1371/journal.pone.0029309PMC PMC3248444
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Research works printed but not linked: 76

  1. JP Hugot, 2001, Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease., Nature, 411, 599, 10.1038/35079107 · DOI · Paper page
  2. Y Ogura, 2001, A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease., Nature, 411, 603, 10.1038/35079114 · DOI · Paper page
  3. RH Duerr, 2006, A genome-wide association study identifies IL23R as an inflammatory bowel disease gene., Science, 314, 1461, 10.1126/science.1135245 · DOI · Paper page
  4. J Glas, 2007, rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants., PLoS ONE, 2, e819, 10.1371/journal.pone.0000819 · DOI
  5. J Hampe, 2007, A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1., Nat Genet, 39, 207, 10.1038/ng1954 · DOI
  6. J Glas, 2008, The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population., Am J Gastroenterol, 103, 682, 10.1111/j.1572-0241.2007.01694.x · DOI
  7. C Libioulle, 2007, Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4., PLoS Genet, 3, e58, 10.1371/journal.pgen.0030058 · DOI
  8. S Brand, 2009, Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease., Gut, 58, 1152, 10.1136/gut.2008.163667 · DOI
  9. K Kawamura, 2005, Differentiation, maturation, and survival of dendritic cells by osteopontin regulation., Clin Diagn Lab Immunol, 12, 206, 10.1128/CDLI.12.1.206-212.2005 · DOI
  10. A O'Regan, 2000, Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation., Int J Exp Pathol, 81, 373, 10.1046/j.1365-2613.2000.00163.x · DOI
  11. CM Giachelli, 2000, Osteopontin: a versatile regulator of inflammation and biomineralization., Matrix Biol, 19, 615, 10.1016/S0945-053X(00)00108-6 · DOI
  12. R Mori, 2008, Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring., J Exp Med, 205, 43, 10.1084/jem.20071412 · DOI
  13. T Uede, 2011, Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases., Pathol Int, 61, 265, 10.1111/j.1440-1827.2011.02649.x · DOI
  14. SA Lund, 2009, The role of osteopontin in inflammatory processes., J Cell Commun Signal, 3, 311, 10.1007/s12079-009-0068-0 · DOI
  15. AC Renkl, 2005, Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype., Blood, 106, 946, 10.1182/blood-2004-08-3228 · DOI
  16. S Ohshima, 2002, Enhanced local production of osteopontin in rheumatoid joints., J Rheumatol, 29, 2061
  17. L Bazzichi, 2009, Osteopontin is associated with increased arterial stiffness in rheumatoid arthritis., Mol Med, 15, 402, 10.2119/molmed.2009.00052 · DOI
  18. H Sennels, 2008, Circulating levels of osteopontin, osteoprotegerin, total soluble receptor activator of nuclear factor-kappa B ligand, and high-sensitivity C-reactive protein in patients with active rheumatoid arthritis randomized to etanercept alone or in combination with methotrexate., Scand J Rheumatol, 37, 241, 10.1080/03009740801910320 · DOI
  19. E Buommino, 2009, Osteopontin: a new emerging role in psoriasis., Arch Dermatol Res, 301, 397, 10.1007/s00403-009-0939-5 · DOI
  20. MH Vogt, 2010, Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers., Mult Scler, 16, 443, 10.1177/1352458509359723 · DOI
  21. G Murugaiyan, 2008, Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis., J Immunol, 181, 7480, 10.4049/jimmunol.181.11.7480 · DOI
  22. M Braitch, 2008, Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis., Arch Neurol, 65, 633, 10.1001/archneur.65.5.633 · DOI
  23. M Niino, 2003, Genetic polymorphisms of osteopontin in association with multiple sclerosis in Japanese patients., J Neuroimmunol, 136, 125, 10.1016/S0165-5728(03)00004-3 · DOI · Paper page
  24. T Standal, 2004, Role of osteopontin in adhesion, migration, cell survival and bone remodeling., Exp Oncol, 26, 179
  25. R Zohar, 1998, Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration., Eur J Oral Sci, 106, 401, 10.1111/j.1600-0722.1998.tb02206.x · DOI
  26. MD Begum, 2007, Suppression of the bacterial antigen-specific T cell response and the dendritic cell migration to the lymph nodes by osteopontin., Microbiol Immunol, 51, 135, 10.1111/j.1348-0421.2007.tb03884.x · DOI
  27. AW O'Regan, 2000, Osteopontin augments CD3-mediated interferon-gamma and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells., J Leukoc Biol, 68, 495, 10.1189/jlb.68.4.495 · DOI
  28. Y Koguchi, 2002, Penicillium marneffei causes osteopontin-mediated production of interleukin-12 by peripheral blood mononuclear cells., Infect Immun, 70, 1042, 10.1128/IAI.70.3.1042-1048.2002 · DOI
  29. Y Koguchi, 2003, High plasma osteopontin level and its relationship with interleukin-12-mediated type 1 T helper cell response in tuberculosis., Am J Respir Crit Care Med, 167, 1355, 10.1164/rccm.200209-1113OC · DOI
  30. N Gassler, 2002, Expression of osteopontin (Eta-1) in Crohn disease of the terminal ileum., Scand J Gastroenterol, 37, 1286, 10.1080/003655202761020560 · DOI
  31. J Agnholt, 2007, Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease., Scand J Immunol, 65, 453, 10.1111/j.1365-3083.2007.01908.x · DOI
  32. JN Gordon, 2005, Osteopontin: a new addition to the constellation of cytokines which drive T helper cell type 1 responses in Crohn's disease., Gut, 54, 1213, 10.1136/gut.2004.063412 · DOI
  33. T Sato, 2005, Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response., Gut, 54, 1254, 10.1136/gut.2004.048298 · DOI
  34. R Mishima, 2007, High plasma osteopontin levels in patients with inflammatory bowel disease., J Clin Gastroenterol, 41, 167, 10.1097/MCG.0b013e31802d6268 · DOI
  35. H Masuda, 2005, Osteopontin expression in ulcerative colitis is distinctly different from that in Crohn's disease and diverticulitis., J Gastroenterol, 40, 409, 10.1007/s00535-005-1567-2 · DOI
  36. H Masuda, 2003, Distinct gene expression of osteopontin in patients with ulcerative colitis., J Surg Res, 111, 85, 10.1016/S0022-4804(03)00046-5 · DOI
  37. AP da Silva, 2009, Osteopontin attenuation of dextran sulfate sodium-induced colitis in mice., Lab Invest, 89, 1169, 10.1038/labinvest.2009.80 · DOI
  38. J Zhong, 2006, Osteopontin deficiency protects mice from Dextran sodium sulfate-induced colitis., Inflamm Bowel Dis, 12, 790, 10.1097/00054725-200608000-00015 · DOI
  39. K Heilmann, 2008, Osteopontin as two-sided mediator of intestinal inflammation., J Cell Mol Med, 13, 1162, 10.1111/j.1582-4934.2008.00428.x · DOI
  40. N Barizzone, 2011, Association of osteopontin regulatory polymorphisms with systemic sclerosis., Hum Immunol, 72, 930, 10.1016/j.humimm.2011.06.009 · DOI
  41. A Chiocchetti, 2010, The osteopontin gene +1239A/C single nucleotide polymorphism is associated with type 1 diabetes mellitus in the Italian population., Int J Immunopathol Pharmacol, 23, 263, 10.1177/039463201002300124 · DOI
  42. K Schmidt-Petersen, 2009, Osteopontin gene variation and cardio/cerebrovascular disease phenotypes., Atherosclerosis, 206, 209, 10.1016/j.atherosclerosis.2009.02.015 · DOI
  43. R Marciano, 2009, Association of alleles at polymorphic sites in the Osteopontin encoding gene in young type 1 diabetic patients., Clin Immunol, 131, 84, 10.1016/j.clim.2008.11.004 · DOI
  44. MS Silverberg, 2005, Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology., Can J Gastroenterol, 19, 5, 10.1155/2005/269076 · DOI
  45. J Glas, 2010, Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset., PLoS ONE, 5, e10373, 10.1371/journal.pone.0010373 · DOI
  46. J Glas, 2011, CEACAM6 gene variants in inflammatory bowel disease., PLoS ONE, 6, e19319, 10.1371/journal.pone.0019319 · DOI
  47. J Glas, 2010, The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants., PLoS ONE, 5, e14466, 10.1371/journal.pone.0014466 · DOI
  48. J Glas, 2009, Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease., Am J Gastroenterol, 104, 1737, 10.1038/ajg.2009.163 · DOI
  49. A Chiocchetti, 2005, Osteopontin gene haplotypes correlate with multiple sclerosis development and progression., J Neuroimmunol, 163, 172, 10.1016/j.jneuroim.2005.02.020 · DOI
  50. S Han, 2008, Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction., PLoS One, 3, e0001757, 10.1371/journal.pone.0001757 · DOI
  51. A Maver, 2009, Genetic variation in osteopontin gene is associated with susceptibility to sarcoidosis in Slovenian population., Dis Markers, 27, 295, 10.1155/2009/864313 · DOI
  52. SN Kariuki, 2009, Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus., Genes Immun, 10, 487, 10.1038/gene.2009.15 · DOI
  53. AC Forton, 2002, An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus., Hum Mutat, 19, 459, 10.1002/humu.9025 · DOI
  54. J Seiderer, 2007, Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD., Inflamm Bowel Dis, 14, 437, 10.1002/ibd.20339 · DOI
  55. S Schmechel, 2008, Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status., Inflamm Bowel Dis, 14, 204, 10.1002/ibd.20315 · DOI
  56. A Franke, 2010, Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci., Nat Genet, 42, 1118, 10.1038/ng.717 · DOI · Paper page
  57. CA Anderson, 2011, Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47., Nat Genet, 43, 246, 10.1038/ng.764 · DOI
  58. J Glas, 2011, Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease., Inflamm Bowel Dis, 17, 1917, 10.1002/ibd.21562 · DOI
  59. S D'Alfonso, 2005, Two single-nucleotide polymorphisms in the 5′ and 3′ ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus., Arthritis Rheum, 52, 539, 10.1002/art.20808 · DOI
  60. AP Xu, 2007, Osteopontin gene polymorphism in association with systemic lupus erythematosus in Chinese patients., Chin Med J (Engl), 120, 2124, 10.1097/00029330-200712010-00011 · DOI
  61. R Marciano, 2006, A polymorphic variant inside the osteopontin gene shows association with disease course in oligoarticular juvenile idiopathic arthritis., Ann Rheum Dis, 65, 662, 10.1136/ard.2005.040626 · DOI
  62. AE Hensiek, 2003, Osteopontin gene and clinical severity of multiple sclerosis., J Neurol, 250, 943, 10.1007/s00415-003-1120-2 · DOI
  63. A Mas, 2007, The 795CT polymorphism in osteopontin gene is not associated with multiple sclerosis in a Spanish population., Mult Scler, 13, 250, 10.1177/1352458506070944 · DOI
  64. E Urcelay, 2005, Osteopontin gene polymorphisms in Spanish patients with rheumatoid arthritis., J Rheumatol, 32, 405
  65. S Brand, 2006, IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration., Am J Physiol Gastrointest Liver Physiol, 290, G827, 10.1152/ajpgi.00513.2005 · DOI
  66. K Sugimoto, 2008, IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis., J Clin Invest, 118, 534
  67. LA Zenewicz, 2008, Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease., Immunity, 29, 947, 10.1016/j.immuni.2008.11.003 · DOI
  68. S Brand, 2007, IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro., Am J Physiol Gastrointest Liver Physiol, 292, G1019, 10.1152/ajpgi.00239.2006 · DOI
  69. SJ Aujla, 2008, IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia., Nat Med, 14, 275, 10.1038/nm1710 · DOI
  70. Y Zheng, 2008, Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens., Nat Med, 14, 282, 10.1038/nm1720 · DOI
  71. L Liaw, 1998, Altered wound healing in mice lacking a functional osteopontin gene (spp1)., J Clin Invest, 101, 1468, 10.1172/JCI2131 · DOI
  72. G Chen, 2010, Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis., Arthritis Rheum, 62, 2900, 10.1002/art.27603 · DOI
  73. ML Shinohara, 2008, Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin., Immunity, 29, 68, 10.1016/j.immuni.2008.05.008 · DOI
  74. G Murugaiyan, 2010, Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation., Proc Natl Acad Sci U S A, 107, 11495, 10.1073/pnas.1002099107 · DOI
  75. G Murugaiyan, 2009, IL-27 is a key regulator of IL-10 and IL–17 production by human CD4+ T cells., J Immunol, 183, 2435, 10.4049/jimmunol.0900568 · DOI
  76. J Diegelmann, 2011, A novel role for IL-27 as mediator of intestinal epithelial barrier protection mediated via differential STAT signaling and induction of antibacterial and anti-inflammatory proteins., J Biol Chem

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Metadata

Authors
Glas, J., Seiderer, J., Bayrle, C., Wetzke, M., Fries, C., Tillack, C., Olszak, T., Beigel, F., Steib, C., Friedrich, M., Diegelmann, J., Czamara, D., & Brand, S.
Venue
PLoS ONE
Publisher
Public Library of Science (PLoS)
Published
2011-12-29
Volume
6
Issue
12
Pages
e29309
ISSN
1932-6203
DOI
10.1371/journal.pone.0029309
PMC
PMC3248444
Cited by
42
References
0
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified)

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