Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies

Codolo, Gaia, Plotegher, Nicoletta, Pozzobon, Tommaso, Brucale, Marco, Tessari, Isabella, Bubacco, Luigi, de Bernard, Marina·2013·PLoS ONE

Cited by (587)

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  75. References
    Christopher A. Shaw · 2017 · Wiley eBooks
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  77. Ester Prodrug NLRP3 Inflammasome Inhibitor NT-0796 is Brain Active due to Activation by Local Expression of Carboxylesterase-1
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  79. Age-associated diseases: the role of the inflammasome complex
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  80. The potential role of CGRP in synuclein-associated neurodegenerative disorders
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  81. hCeO2@CA-074Me Nanoparticles Alleviate Inflammation and Improve Osteogenic Microenvironment by Regulating the CTSB-NLRP3 Signaling Pathway
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  82. Neuropharmacological Interventions of Plant Origin for Parkinson's Disease: A Comprehensive Appraisal
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  83. C-Reactive Protein and Neurodegenerative Diseases
    Inês Lopes Cardoso, Maria Fernanda C. Leal · 2020 · Springer eBooks
  84. Current and future clinical utilities of Parkinson’s disease and dementia biomarkers: can they help us conquer the disease?
    Gilbert J. Ho, Yoshiki Takamatsu, Masaaki Waragai, Ryoko Wada, Shuei Sugama, Takato Takenouchi, Masayo Fujita, Alysha Ali, Mindy Hsin-I Hsieh, Makoto Hashimoto · 2019 · Expert Review of Neurotherapeutics
  85. Unraveling Neurodegeneration: Common Molecular Mechanisms and Novel Therapeutic Concepts in Major Neurodegenerative Disorders
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  86. Emerging targets signaling for inflammation in Parkinson’s disease drug discovery
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  87. Influence of Cigarette Aerosol in Alpha-Synuclein Oligomerization and Cell Viability in SH-SY5Y: Implications for Parkinson’s Disease
    Yuxin Shen, Pe-Shuen Lee, Ming-Chu Teng, Jhih-Hong Huang, Chia C. Wang, Hsiu‐Fang Fan · 2024 · ACS Chemical Neuroscience
  88. The genetic advantage of healthy centenarians: unraveling the central role of NLRP3 in exceptional healthspan
    Stefan F. F. Verlinden · 2024 · Frontiers in Aging
  89. Therapeutic potential of Canna edulis RS3-resistant starch in alleviating neuroinflammation and apoptosis in a Parkinson's disease rat model
    Qian-Kun He, Xueyong Wang, Wei Hu, Jing Cai, Peng Chen, Ming-wei Liu, Yuan-Hua Wu · 2024 · Heliyon
  90. Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia
    Karl E. Biggs, Emma N. Fikse, Faith L. Anderson, Arminja Nadine Kettenbach, Matthew C. Havrda · 2025 · Journal of Neuroscience
  91. Inflammasome-Mediated Inflammation in Neurodegenerative Diseases
    Jun Young Park, Yeo Wool Kang, Won Gil Cho · 2019 · The Open Neurology Journal
  92. Alpha-synuclein promotes dopaminergic neuron death in Parkinson’s disease through microglial and NLRP3 activation
    Sarah Klein · 2020 · USURJ University of Saskatchewan Undergraduate Research Journal
  93. RETRACTED ARTICLE: Role of TLR2 and TLR4 Signaling in Parkinson’s Disease: An Insight into Associated Therapeutic Potential
    Gagandeep Kaur, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Arun Kumar, Sandeep Arora, SIMONA GABRIELA BUNGAU · 2021 · Journal of Molecular Neuroscience · Retracted
  94. How cytosolic compartments play safeguard functions against neuroinflammation and cell death in cerebral ischemia
    Fari Ryan, Seyed Esmaeil Khoshnam, Fariba Khodagholi, Ghorbangol Ashabi, Abolhassan Ahmadiani · 2021 · Metabolic Brain Disease
  95. The Role of Inflammasomes in the Pathogenesis of Neurodegenerative Diseases
    Denis V. Shevchuk, Anna A. Abramova, Mariya N. Zakharova · 2022 · Neurochemical Journal
  96. Potential Impact of Bioactive Compounds as NLRP3 Inflammasome Inhibitors: An Update
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  97. Sulphonylureas as Adjunct Therapeutic Agents in the Treatment of Autoimmune Conditions: A Narrative Review
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  98. Negative regulatory mechanisms of NLRP3 inflammasome
    Wei Zhao, Ying QIN · 2018 · Scientia Sinica Vitae
  99. An Overview of Alpha Synuclein Protein and Its Role in Parkinson’s disease
    Zeynep Bengisu Kaya, Pergin Atilla · 2021 · Acta Medica
  100. Inflammaging Targets
    Miriam Capri, Claudio Franceschi, Stefano Salvioli · 2019 · Elsevier eBooks