The DOI matches its Crossref record.
Use of the Local False Discovery Rate for Identification of Metabolic Biomarkers in Rat Urine Following Genkwa Flos-Induced Hepatotoxicity
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Various animal studies and in vitro models have identified changes in the metabolomic profile in the presence of DILI [13,16,22,23,24,25,26,27,28,29,30,31,32,33,34,35].”
From Metabolomic Analysis of Pediatric Patients with Idiosyncratic Drug-Induced Liver Injury According to the Updated RUCAM (2023) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 24
- RS Plumb, 2002, Metabonomics: the use of electrospry mass spectrometry coupled to reversed-phase liquid chromatography show a potential for the screening of rat urine in drug development, Rapid Commun Mass Spectrom[J], 16, 1991, 10.1002/rcm.813 · DOI
- R Goodacre, 2004, Metabolomics by numbers: acquiring and understanding global metabolite data, Trends Biotechnol, 22, 245, 10.1016/j.tibtech.2004.03.007 · DOI
- LJ Sweetlove, 2005, Regulation of metabolic networks: understanding metabolic complexity in the systems biology era, New Phytol, 168, 9, 10.1111/j.1469-8137.2005.01513.x · DOI
- RS Plumb, 2003, Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids, Rapid Commun Mass Spectrom [J], 17, 2632, 10.1002/rcm.1250 · DOI
- EM Lenz, 2004, A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependant changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity, Analyst, 129, 535, 10.1039/b400159c · DOI
- ID Wilson, 2005, HPLC-MS-based methods for the study of metabonomics, J Chromatography B, 817, 67, 10.1016/j.jchromb.2004.07.045 · DOI
- AR Fernie, 2004, Metabolite profiling: from diagnostics to systems biology, Nat Rev Mole Cell Biol, 5, 763, 10.1038/nrm1451 · DOI
- C Bettcher, 2007, Evaluation of matrix effects in metabolite profiling based on capillary liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry, Anal Chem, 79, 1507, 10.1021/ac061037q · DOI
- O Fiehn, 2001, Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks, Comparative and Functional Genomics, 2, 155, 10.1002/cfg.82 · DOI
- LM Raamsdonk, 2001, A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations, Nature biotechnology, 19, 45, 10.1038/83496 · DOI
- JC Lindon, 2001, Pattern recognition methods and applications in biomedical magnetic resonance, Progress in Nuclear Magnetic Resonance Spectroscopy, 39, 1, 10.1016/S0079-6565(00)00036-4 · DOI
- S Moco, 2007, Metabolomics technologies and metabolite identification, TrAC Trends in Analytical Chemistry, 26, 855, 10.1016/j.trac.2007.08.003 · DOI
- JC Lindon, 2006, Metabonomics techniques and applications to pharmaceutical research & development, Pharmaceutical research, 23, 1075, 10.1007/s11095-006-0025-z · DOI
- GEP Box, 1954, Some theorems on quadratic forms applied in the study of analysis of variance problems: effect of inequality of variance in one-way classification, Ann Math Statist, 25, 33
- Wall M., Rechtsteiner A., Rocha L. (2003). Singular value decomposition and principal component analysis. A practical approach to microarray data analysis, 91–109. · DOI
- O Alter, 2000, Singular value decomposition for genome-wide expression data processing and modeling, Proc Natl Acad Sci USA, 97, 10101, 10.1073/pnas.97.18.10101 · DOI
- A Fukushima, 2011, Metabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach, BMC Systems biology, 5, 1, 10.1186/1752-0509-5-1 · DOI
- Efron B (2010) Large-scale inference: empirical Bayes methods for estimation, testing, and prediction (Vol. 1). Cambridge University Press. · DOI
- Geng L, Ma C, Zhang L, Yang G, Cui Y, <etal>et al</etal>.. (2012) Metabonomic study of Genkwa Flos-induced hepatotoxicity and effect of herb-processing procedure on toxicity. Phytother Res. DOI:10.1002/ptr.4748. · DOI
- R Rousseau, 2008, Comparison of some chemometric tools for metabonomics biomarker identification, Chemometrics and Intelligent Laboratory Systems, 91, 54, 10.1016/j.chemolab.2007.06.008 · DOI
- B Efron, 2004, Large-scale simultaneous hypothesis testing: the choice of a null hypothesis, Journal of the American Statistical Association, 99, 96, 10.1198/016214504000000089 · DOI · Paper page
- B Efron, 2002, Empirical Bayes methods and false discovery rates for microarrays, Genetic epidemiology, 23, 70, 10.1002/gepi.1124 · DOI · Paper page
- Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B (Methodological) 289–300. · DOI · Paper page
- Z Yang, 2013, Empirical Bayes estimation of posterior probabilities of enrichment: A comparative study of five estimators of the local false discovery rate, BMC Bioinformatics, 14(1), 87, 10.1186/1471-2105-14-87 · DOI
Cited by
Sorted by citations
Andújar-Vera, F., Alés-Palmer, M. L., Muñoz-de-Rueda, P., Iglesias-Baena, I., & Ocete-Hita, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713562 · Cited by 10
Metadata
- Authors
- Li, Z., Li, Q., Geng, L., Chen, X., & Bi, K.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2013-07-02
- Volume
- 8
- Issue
- 7
- Pages
- e67451
- ISSN
- 1932-6203
- PMC
- PMC3699555
- Cited by
- 7
- References
- 0
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review