The DOI matches its Crossref record; 60 of the 62 references it cites were found in a registry or an index.
Prevalence and Associated Positive Psychological Variables of Depression and Anxiety among Chinese Cervical Cancer Patients: A Cross-Sectional Study
Open accessAbstract
BACKGROUND: The prevalence of depression and anxiety and its associated factors in cervical cancer are not well evaluated in China. Meanwhile, with increasing attention given to positive psychological variables in oncology field, there is a need to conduct a study to explore the integrative effects of positive psychological variables on depression/anxiety so as to provide patients a more holistic cancer care. The aim of this study was to assess the prevalence of depression/anxiety as well as the integrative effects of hope, optimism and general self-efficacy on depression/anxiety among Chinese cervical cancer patients. METHODS: A multi-centre, cross-sectional study was conducted of consecutive inpatients at the Liaoning Cancer Hospital & Institute and the Shengjing Hospital of China Medical University in Liaoning Province, northeast China. A total of 224 cervical cancer patients eligible for this study completed questionnaires on demographic and clinic variables, Hospital Anxiety and Depression Scale, Herth Hope Index, Life Orientation Scale-Revised, and General Self-Efficacy Scale during February and August 2013. RESULTS: The prevalence of depression and anxiety was 52.2% and 65.6% in cervical cancer patients. The anxiety score was significantly higher in patients at the period of 4-6 months after diagnose and at cancer stage II. Hierarchical regression analyses indicated that hope, optimism and general self-efficacy as a whole accounted for 31.3% variance of depression and 35.6% variance of anxiety. Under standardized estimate (β) sequence, hope, optimism and general self-efficacy significantly associated with depression, respectively; hope and optimism were also significant individual predictors of anxiety. CONCLUSIONS: The high prevalence of depression and anxiety among cervical cancer patients should receive more attention in Chinese medical settings. More importantly, efforts to develop the integrated psychosocial interventions are effective and necessary to alleviate depression/anxiety in cervical cancer patients by synthesizing and integrating the individual protective effects of hope, optimism and general self-efficacy.
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“For instance, hope is negatively associated with depression, anxiety, and psychological distress among cancer patients [19–22].”
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“%) and 65.6% (possible cases: 24.1%; probable cases: 41.5%), and the prevalence of co-morbidity was 45.5% in our study, indicating that depression and anxiety coexisted in Chinese cervical cancer patients, similar to this situation in China and foreign countries [5,49].”
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Experiences of Women Living with Cervical Cancer: A Study in the Tamale Metropolis
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InfluentialScripcariu, I.-S., Matasariu, D. R., Socolov, D. G., Anton, G., Balan, R. A., Ursu, R. G., Radu, V. D., Avasiloaiei, A. L., Ionescu, C., Visternicu, M., et al. (2026) · Medical Sciences · doi:10.3390/medsci14060657
“In a cross-sectional study of 224 patients, Chinese researchers (2013) [6] reported a prevalence of depression of approximately 52.2%, with a high co-occurrence of anxiety, and found that psychosocial resources, including hope and optimism, were associated with lower depression scores.”
Influential
Metadata
- Authors
- Yang, Y.-L., Liu, L., Wang, X.-X., Wang, Y., & Wang, L.
- Affiliations
- China Medical University (CN)
- Corresponding author
- Wang, Lie
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-04-10
- Volume
- 9
- Issue
- 4
- Pages
- e94804
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3983270
- OpenAlex
- W2072487399
- Cited by
- 108
- References
- 62
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 9 · 2023: 16 · 2022: 12 · 2021: 12 · 2020: 9 · 2019: 7 · 2018: 6 · 2017: 8 · 2016: 9 · 2015: 4 · 2014: 2
- FWCI
- 3.70
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- China Medical University
- Shengjing Hospital
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Applied Psychology › Optimism, Hope, and Well-being
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Keywords
- cervical cancer, depression, anxiety, hope, optimism, general self-efficacy, prevalence, psychosocial interventions, Chinese patients, tumor stage, time since diagnosis
- MeSH terms
- Adaptation, Psychological, Adult, Aged, Anxiety, Uterine Cervical Neoplasms, China, Cross-Sectional Studies, Depression, Female, Humans, Middle Aged, Psychiatric Status Rating Scales, Quality of Life, Prevalence, Self Efficacy, Young Adult, Hope
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