Inter-individual variability in the adaptive responses to endurance and sprint interval training: a randomized crossover study.
Open accessAbstract
The current study examined the adaptive response to both endurance (END) and sprint interval training (SIT) in a group of twenty-one recreationally active adults. All participants completed three weeks (four days/ week) of both END (30 minutes at ~65% VO2peak work rate (WR) and SIT (eight, 20-second intervals at ~170% VO2peak WR separated by 10 seconds of active rest) following a randomized crossover study design with a three-month washout period between training interventions. While a main effect of training was observed for VO2peak, lactate threshold, and submaximal heart rate (HR), considerable variability was observed in the individual responses to both END and SIT. No significant positive relationships were observed between END and SIT for individual changes in any variable. Non-responses were determined using two times the typical error (TE) of measurement for VO2peak (0.107 L/min), lactate threshold (15.7 W), and submaximal HR (10.7bpm). Non-responders in VO2peak, lactate threshold, and submaximal HR were observed following both END and SIT, however, the individual patterns of response differed following END and SIT. Interestingly, all individuals responded in at least one variable when exposed to both END and SIT. These results suggest that the individual response to exercise training is highly variable following different training protocols and that the incidence of non-response to exercise training may be reduced by changing the training stimulus for non-responders to three weeks of END or SIT.
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No global non-responders exist.
“Remarkably, it has also been highlighted that no “global non-responders” exist (Ross et al., 2015; Bonafiglia et al., 2016; Montero and Lundby, 2017; Pickering and Kiely, 2017c, 2018b; Toigo, 2019).”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Bonafiglia et al., 2016
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References 47 · Cited by 172
- Authors
- Bonafiglia, J. T., Rotundo, M. P., Whittall, J. P., Scribbans, T. D., Graham, R. B., & Gurd, B. J.
- Affiliations
- Queen's University (CA)
- University of Ottawa (CA)
- Corresponding author
- Gurd, Brendon J.
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-12-09
- Volume
- 11
- Issue
- 12
- Pages
- e0167790
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC5147982
- OpenAlex
- W2559920125
- Cited by
- 172
- References
- 47
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 17 · 2023: 16 · 2022: 17 · 2021: 20 · 2020: 17 · 2019: 27 · 2018: 27 · 2017: 16
- FWCI
- 47.87
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Natural Sciences and Engineering Research Council of Canada (402635)
- Canadian Foundation for Innovation (25476)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Physical Performance
- Keywords
- interindividual variability, exercise training response, endurance training, sprint interval training, peak oxygen uptake, lactate threshold, submaximal heart rate, non-responders, typical error of measurement, training stimulus
- MeSH terms
- High-Intensity Interval Training, Adaptation, Physiological, Female, Heart Rate, Humans, Male, Oxygen Consumption, Physical Endurance, Running, Cross-Over Studies, Lactic Acid, Young Adult
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