Correction: A standardised framework to identify optimal animal models for efficacy assessment in drug development
Open accessAbstract
[This corrects the article DOI: 10.1371/journal.pone.0218014.].
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In much of the academic literature, important model features are chosen post hoc by the authors and not prospectively by an independent third party with expertise in the therapeutic problem at hand.
“But even here there is a common problem in much of the academic literature: the important model features are chosen post hoc by the authors and not prospectively by an independent third party that has expertise in the therapeutic problem at hand10.”
From Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology (2022) · cites this paper as [10]
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Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology
Ewart, L., Apostolou, A., Briggs, S. A., Carman, C. V., Chaff, J. T., Heng, A. R., Jadalannagari, S., Janardhanan, J., Jang, K.-J., Joshipura, S. R., et al. (2022) · Communications Medicine · doi:10.1038/s43856-022-00209-1 · Cited by 337 · see citing works
- Authors
- Ferreira, G. S., Veening-Griffioen, D. H., Boon, W. P. C., Moors, E. H. M., Gispen-de Wied, C. C., Schellekens, H., & van Meer, P. J. K.
- ORCID
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2019-07-22
- Volume
- 14
- Issue
- 7
- Pages
- e0220325
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W4235921548
- Cited by
- 22
- References
- 0
- Citations by year
- 2026: 3 · 2025: 5 · 2023: 1 · 2022: 3 · 2021: 6 · 2020: 4
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Health Sciences › Veterinary › Small Animals › Veterinary Pharmacology and Anesthesia
- Keywords
- animal models, drug efficacy evaluation, drug development
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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