Evaluating deep learning-based melanoma classification using immunohistochemistry and routine histology: A three center study

Wies, Christoph; Schneider, Lucas; Haggenmüller, Sarah; Bucher, Tabea-Clara; Hobelsberger, Sarah; Heppt, Markus V.; Ferrara, Gerardo; Krieghoff-Henning, Eva I.; Brinker, Titus J.

doi:10.1371/journal.pone.0297146

Evaluating deep learning-based melanoma classification using immunohistochemistry and routine histology: A three center study

Pathologists routinely use immunohistochemical (IHC)-stained tissue slides against MelanA in addition to hematoxylin and eosin (H&E)-stained slides to improve their accuracy in diagnosing melanomas. The use of diagnostic Deep Learning (DL)-based support systems for automated examination of tissue…