Explainability in action: A metric-driven assessment of local explanations for healthcare tabular models
Open accessAbstract
Explainable AI (XAI) is increasingly used in clinical machine learning, yet quantitative evaluation of explanation quality is often reported inconsistently across methods and datasets. We present a reproducible, metric-driven framework for evaluating XAI methods on healthcare tabular data. The framework consolidates six established, family-specific metrics, fidelity, simplicity, consistency, robustness, precision, and coverage, into explicit equations; pairs them with a pre-specified focal-model protocol; and releases open-source code with a method–metric applicability map. We evaluate LIME, SHAP, Anchors, EBM, and TabNet across four public healthcare tabular datasets. Post-hoc explainers are applied to a single selected Random Forest focal predictor to control model-induced variability, whereas EBM and TabNet are assessed through their native interpretability mechanisms. Global explanation summaries are reported descriptively only. The results show that SHAP/TreeSHAP provides exact score reconstruction for the Random Forest setting, while LIME produces simpler but lower-fidelity explanations with greater instance-level variability. LIME and SHAP show the strongest rank agreement among the evaluated pairs, although agreement varies across datasets. TabNet often yields compact native explanations, but these must be interpreted alongside its dataset-specific predictive performance. EBM and TabNet show low sensitivity under the fixed Gaussian-jitter robustness protocol, while Anchors produces high-precision rules with reduced coverage at stricter thresholds. Overall, the framework enables controlled comparison under explicit method–metric and focal-model assumptions, supporting more transparent XAI selection for tabular machine learning. Although demonstrated in healthcare, the framework is transferable to other high-stakes tabular domains. Source code: https://github.com/matifq/XAI_Tab_Health .
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Ali, S., Abuhmed, T., El-Sappagh, S., Muhammad, K., Alonso-Moral, J. M., Confalonieri, R., Guidotti, R., Del Ser, J., Díaz-Rodríguez, N., & Herrera, F. (2023) · Information Fusion · doi:10.1016/j.inffus.2023.101805 · Cited by 1,762 · cited 1× · see citing works
“Fidelity [46] evaluates how accurately an XAI method replicates the behavior of the original predictive model.”
Antoniadi, A. M., Du, Y., Guendouz, Y., Wei, L., Mazo, C., Becker, B. A., & Mooney, C. (2021) · Applied Sciences · doi:10.3390/app11115088 · Cited by 629 · see citing works
Nauta, M., Trienes, J., Pathak, S., Nguyen, E., Peters, M., Schmitt, Y., Schlötterer, J., van Keulen, M., & Seifert, C. (2023) · ACM Computing Surveys · doi:10.1145/3583558 · Cited by 590 · see citing works
Accurate intelligible models with pairwise interactions
Lou, Y., Caruana, R., Gehrke, J., & Hooker, G. (2013) · Proceedings of the 19th ACM SIGKDD international conference on Knowledge discovery and data mining · doi:10.1145/2487575.2487579 · Cited by 564 · see citing works
Explainable AI for clinical and remote health applications: A survey on tabular and time series data
Di Martino, F., & Delmastro, F. (2023) · Artificial Intelligence Review · doi:10.1007/s10462-022-10304-3 · Cited by 216 · see citing works
Explainable AI for 6G Use Cases: Technical Aspects and Research Challenges
Wang, S., Qureshi, M. A., Miralles-Pechuán, L., Huynh-The, T., Gadekallu, T. R., & Liyanage, M. (2024) · IEEE Open Journal of the Communications Society · doi:10.1109/ojcoms.2024.3386872 · Cited by 170 · see citing works
Self-citationUnveiling Explainable <scp>AI</scp> in Healthcare: Current Trends, Challenges, and Future Directions
Noor, A. A., Manzoor, A., Mazhar Qureshi, M. D., Qureshi, M. A., & Rashwan, W. (2025) · WIREs Data Mining and Knowledge Discovery · doi:10.1002/widm.70018 · Cited by 52 · see citing works
Self-citation
Flagged first, then by citations
- Authors
- Qureshi, M. A., Noor, A. A., Manzoor, A., Mazhar Qureshi, M. D., Younus, A., & Rashwan, W.
- Affiliations
- Technological University Dublin (IE)
- University College Dublin (IE)
- National University of Ireland, Maynooth (IE)
- Corresponding author
- Qureshi, M. Atif
- Venue
- PLOS One
- Publisher
- Public Library of Science (PLoS)
- Published
- 2026-07-08
- Volume
- 21
- Issue
- 7
- Pages
- e0351473
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC13345234
- OpenAlex
- W7167702792
- Cited by
- 7
- References
- 7
- Citations by year
- 2026: 7
- FWCI
- 16.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- medRxiv (acceptedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion, cc-by)
- Arrow - TU Dublin (Technological University Dublin) (submittedVersion, cc-by)
- Funders
- Research Ireland (GOIPG/2022/660, GOIPG/2021/1354)
- Research Ireland Centre for Research Training in Machine Learning (18/CRT/6183)
- Research Ireland, ADAPT Research Centre (13/RC/2106_P2)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
- Keywords
- explainable AI, local explanations, explanation quality metrics, tabular machine learning, lime, SHAP, anchors, explainable boosting machine, TabNet, random forest, explanation fidelity, explanation robustness
- MeSH terms
- Machine Learning, Random Forest, Delivery of Health Care, Humans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review