Cited by 7Explainable Artificial Intelligence (XAI)Artificial Intelligence in HealthcareMachine Learning in Healthcare

Explainability in action: A metric-driven assessment of local explanations for healthcare tabular models

Open access
Qureshi, M. Atif, Noor, Abdul Aziz, Manzoor, Awais, Mazhar Qureshi, Muhammad Deedahwar, Younus, Arjumand, Rashwan, Wael·2026·PLOS One

Abstract

Explainable AI (XAI) is increasingly used in clinical machine learning, yet quantitative evaluation of explanation quality is often reported inconsistently across methods and datasets. We present a reproducible, metric-driven framework for evaluating XAI methods on healthcare tabular data. The framework consolidates six established, family-specific metrics, fidelity, simplicity, consistency, robustness, precision, and coverage, into explicit equations; pairs them with a pre-specified focal-model protocol; and releases open-source code with a method–metric applicability map. We evaluate LIME, SHAP, Anchors, EBM, and TabNet across four public healthcare tabular datasets. Post-hoc explainers are applied to a single selected Random Forest focal predictor to control model-induced variability, whereas EBM and TabNet are assessed through their native interpretability mechanisms. Global explanation summaries are reported descriptively only. The results show that SHAP/TreeSHAP provides exact score reconstruction for the Random Forest setting, while LIME produces simpler but lower-fidelity explanations with greater instance-level variability. LIME and SHAP show the strongest rank agreement among the evaluated pairs, although agreement varies across datasets. TabNet often yields compact native explanations, but these must be interpreted alongside its dataset-specific predictive performance. EBM and TabNet show low sensitivity under the fixed Gaussian-jitter robustness protocol, while Anchors produces high-precision rules with reduced coverage at stricter thresholds. Overall, the framework enables controlled comparison under explicit method–metric and focal-model assumptions, supporting more transparent XAI selection for tabular machine learning. Although demonstrated in healthcare, the framework is transferable to other high-stakes tabular domains. Source code: https://github.com/matifq/XAI_Tab_Health .

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1371/journal.pone.0351473

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Authors
Qureshi, M. A., Noor, A. A., Manzoor, A., Mazhar Qureshi, M. D., Younus, A., & Rashwan, W.
Affiliations
  • Technological University Dublin (IE)
  • University College Dublin (IE)
  • National University of Ireland, Maynooth (IE)
Corresponding author
Qureshi, M. Atif
Venue
PLOS One
Published
2026-07-08
Volume
21
Issue
7
Pages
e0351473
ISSN
1932-6203 (ISSN-L)
OpenAlex
W7167702792
Cited by
7
References
7
Citations by year
2026: 7
FWCI
16.24
Type
journal article
Language
en
Open access
Locations
  • PLoS ONE (publishedVersion, cc-by)
  • medRxiv (acceptedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • PubMed Central (publishedVersion, cc-by)
  • Arrow - TU Dublin (Technological University Dublin) (submittedVersion, cc-by)
Funders
  • Research Ireland (GOIPG/2022/660, GOIPG/2021/1354)
  • Research Ireland Centre for Research Training in Machine Learning (18/CRT/6183)
  • Research Ireland, ADAPT Research Centre (13/RC/2106_P2)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
Keywords
explainable AI, local explanations, explanation quality metrics, tabular machine learning, lime, SHAP, anchors, explainable boosting machine, TabNet, random forest, explanation fidelity, explanation robustness
MeSH terms
Machine Learning, Random Forest, Delivery of Health Care, Humans

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review