Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

Cited by (153)

Items 101–153 of 153

  1. Genetic-and-Epigenetic Interspecies Networks for Cross-Talk Mechanisms in Human Macrophages and Dendritic Cells during MTB Infection
    Chengwei Li, Yun‐Lin Lee, Bor‐Sen Chen · 2016 · Frontiers in Cellular and Infection Microbiology
  2. Mycobacterium tuberculosis RpfE-Induced Prostaglandin E2 in Dendritic Cells Induces Th1/Th17 Cell Differentiation
    Hye‐Soo Park, Seunga Choi, Yong Woo Back, Kang-In Lee, Han‐Gyu Choi, Hwa‐Jung Kim · 2021 · International Journal of Molecular Sciences
  3. A novel multivalent tuberculosis vaccine confers protection in a mouse model of tuberculosis
    Kristin Griffiths, Daniel O. Villarreal, David B. Weiner, Shabaana A. Khader · 2016 · Human Vaccines & Immunotherapeutics
  4. Can miRNA Indicate Risk of Illness after Continuous Exposure to M. tuberculosis?
    Cleonardo Augusto da Silva, Arthur Ribeiro-dos-Santos, Wanderson Gonçalves e Gonçalves, Pablo Pinto, Rafael Pompeu Pantoja, Tatiana Vinasco‐Sandoval, André Ribeiro-dos-Santos, Mara Helena Hutz, Amanda Ferreira Vidal, Gilderlânio Santana de Araújo et al. · 2021 · International Journal of Molecular Sciences
  5. Cotreatment With Clofazimine and Rapamycin Eliminates Drug-Resistant Tuberculosis by Inducing Polyfunctional Central Memory T-Cell Responses
    Dhiraj Kumar Singh, Ashima Bhaskar, Isha Pahuja, Aishwarya Shaji, Barnani Moitra, Yufang Shi, Ved Prakash Dwivedi, Gobardhan Das · 2023 · The Journal of Infectious Diseases
  6. Advax4 delta inulin combination adjuvant together with ECMX, a fusion construct of four protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection
    Bruno de Paula Oliveira Santos, Monalisa Martins Trentini, Renato Beilner Machado, Mara Rúbia Nunes Celes, André Kipnis, Nikolai Petrovsky, Ana Paula Junqueira‐Kipnis · 2017 · Human Vaccines & Immunotherapeutics
  7. A multiple T cell epitope comprising DNA vaccine boosts the protective efficacy of Bacillus Calmette–Guérin (BCG) against Mycobacterium tuberculosis
    Sudeep K. Maurya, Mohammad Aqdas, Deepjyoti Kumar Das, Sanpreet Singh, Sajid Nadeem, Gurpreet Kaur, Javed Naim Agrewala · 2020 · BMC Infectious Diseases
  8. Strategies to Improve BCG Vaccine Efficacy
    Prerna Bali, Sultan Tousif, Gobardhan Das, Luc Van Kaer · 2015 · Immunotherapy
  9. Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System
    Ting-Yu Angela Liao, Alice Lau, Sunil Joseph, Vesa Pekka Hytönen, Zakaria Hmama · 2015 · PLoS ONE
  10. Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice
    Yu-Min Chuang, Michael L. Pinn, Petros C. Karakousis, Chien‐Fu Hung · 2018 · Frontiers in Cellular and Infection Microbiology
  11. Cell Differentiation Degree as a Factor Determining the Role for Different T-Helper Populations in Tuberculosis Protection
    Irina V. Lyadova, Irina Nikitina · 2019 · Frontiers in Immunology
  12. Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy
    Linna Wei, Liping Liu, Zudi Meng, Kai Qi, Xuehan Gao, Jihong Feng, Junmin Luo · 2024 · Inflammation Research
  13. Biapenem, a Carbapenem Antibiotic, Elicits Mycobacteria Specific Immune Responses and Reduces the Recurrence of Tuberculosis
    Isha Pahuja, Akanksha Verma, Antara Ghoshal, Suparba Mukhopadhyay, Anjna Kumari, Aishwarya Shaji, Shivam Chaturvedi, Ved Prakash Dwivedi, Ashima Bhaskar · 2023 · Microbiology Spectrum
  14. Vaccine efficacy of a Mycobacterium tuberculosis Beijing‐specific proline‐glutamic acid (PE) antigen against highly virulent outbreak isolates
    Kee Woong Kwon, Hong‐Hee Choi, Seung Jung Han, Jong‐Seok Kim, Woo Sik Kim, Hongmin Kim, Lee‐Han Kim, Soon Myung Kang, Jaehun Park, Sung Jae Shin · 2019 · The FASEB Journal
  15. Targeting endogenous gaseous signaling molecules as novel host-directed therapies against tuberculosis infection
    Kamini Gautam, Sheetal Negi, Vikram Saini · 2021 · Free Radical Research
  16. Shared characteristics between Mycobacterium tuberculosis and fungi contribute to virulence.
    Samuel J. Willcocks, B. Wren · 2014 · Future Microbiology
  17. Regulation of antibacterial (antitubercular) immunity mediated by T-helper type-17 lymphocytes
    Кононова Татьяна Евгеньевна, Olga I. Urazova, В. В. Новицкий, Чурина Елена Георгиевна · 2013 · Molecular Biology
  18. Revisiting Immunotherapy in Tuberculosis
    Debapriya Bhattacharya · 2013 · Mycobacterial Diseases
  19. Tuberculosis: Molecular Basis of Pathogenesis
    Phillip P. Salvatore, Ying Zhang · 2017 · Elsevier eBooks
  20. Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen
    Takahiro USHIGUSA, Yoshiyuki Koyama, Tomoko Ito, Kenichi Watanabe, James Kenn CHAMBERS, Aya Hasegawa, Kazuyuki Uchida, Ryoji Kanegi, Shingo Hatoya, Toshio Inaba et al. · 2017 · Journal of Veterinary Medical Science
  21. Mycobacterium tuberculosis effector proteins: functional multiplicity and regulatory diversity
    Lihua Qiang, Yong Zhang, Cui Hua Liu · 2021 · Cellular and Molecular Immunology
  22. A comparative investigation on the role and interaction of EsxA and EsxB in host immune response
    Yuanyang Yi, Hanqing Wang, Lingling Su, Hao Wang, Baojiang Zhang, Yan Su · 2021 · Microbial Pathogenesis
  23. Roles of mycobacterium tuberculosis ESAT-6 in the development of renal injury.
    Yanting Gao, Li Sun, Feng Jiang-min · 2015 · PubMed Central
  24. Expression and Purification of the Recombinant Cytochrome P450 CYP141 Protein of Mycobacterium Tuberculosis as a Diagnostic Tool and Vaccine Production
    Reza Heidari, Mohammad Rabiei, Davood Darban‐Sarokhalil, Amirhooshang Alvandi, Narges Abdian, Ehsan Aryan, Neda Soleimani, Abolfazl Gholipour · 2015 · Iranian Red Crescent Medical Journal
  25. Effects of helminths and Mycobacterium tuberculosis infection on HIV-1
    Emily E. I. M. Mouser, Georgios Pollakis, William A. Paxton · 2012 · Current Opinion in HIV and AIDS
  26. Early secretory antigenic target-6 of Mycobacterium tuberculosis: enigmatic factor in pathogen–host interactions
    Ramesh Chandra Rai, Ved Prakash Dwivedi, Samit Chatterjee, Durbaka V. R. Prasad, Gobardhan Das · 2012 · Microbes and Infection
  27. Evaluation of Mycobacterium tuberculosis Early Secreted Antigenic Target 6 Recombinant Protein as a Diagnostic Marker in Skin Test
    Jale Moradi, Nader Mosavari, Mahmoud Ebrahimi, Reza Arefpajohi, Majid Tebianian · 2014 · Osong Public Health and Research Perspectives
  28. Modulation of Macrophage Responses by CMX, a Fusion Protein Composed of Ag85c, MPT51, and HspX from Mycobacterium tuberculosis
    Adeliane Castro da Costa, Danilo Pires Resende, Bruno de Paula Oliveira Santos, Karina Furlani Zoccal, Lúcia Helena Faccioli, André Kipnis, Ana Paula Junqueira‐Kipnis · 2017 · Frontiers in Microbiology
  29. Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
    Bikul Das, Lekhika Pathak, Sukanya Gayan, Bidisha Pal, Partha Jyoti Saikia, Tutumoni Baishya, Nihar Ranjan Das, Rupam Das, Mallika Maral, Ranjit Mahanta et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Expression and epitope prediction of MPT64 recombinant proteins from clinical isolates of Mycobacterium tuberculosis as immunoserodiagnostic candidates
    Fihiruddin Fihiruddin, Nurul Inayati, Raudatul Jannah, Lalu Unsunnidhal, Asmarani Kusumawati · 2022 · Veterinary World
  31. D er p2 recombinant bacille C almette‐ G uerin priming of bone marrow‐derived dendritic cells suppresses D er p2‐induced T helper17 function in a mouse model of asthma
    Shuoyao Qu, Hai‐Feng Ou‐Yang, Yalong He, Zhikui Li, Jie-Ran Shi, Liqiang Song, Changgui Wu · 2013 · Respirology
  32. Immunoinhibitory effects of anti-tuberculosis therapy induce the host vulnerability to tuberculosis recurrence
    Isha Pahuja, Antara Ghoshal, Ahmed Abdallah Okieh, Akanksha Verma, Kriti Negi, Meetu Agarwal, Nidhi Subhash Chandra, Saurabh Kumar Sharma, Ashima Bhaskar, Ved Prakash Dwivedi · 2024 · Microbiology Spectrum
  33. ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway
    Xiaofei Huang, Yuqun Zeng, Jingru Lin, Huazhen Liu, Chun-Ling Liang, Yuchao Chen, Feifei Qiu, Jonathan S. Bromberg, Zhenhua Dai · 2025 · Frontiers in Immunology
  34. Mycobacterium bovis infection in cattle induces differential expression of prolactin receptor isoforms in macrophages
    Gonzálo López-Rincón, Jose Angel Gutierrez-Pabello, Fernando Díaz-Otero, José Francisco Muñóz-Valle, Ana Laura Pereira-Suárez, Ciro Estrada‐Chávez · 2013 · Comparative Immunology Microbiology and Infectious Diseases
  35. MicroRNA research: The new dawn of Tuberculosis
    Priyanka Mehta · 2020 · Indian Journal of Tuberculosis
  36. Th17: A New Player to be Considered in Tuberculosis Studies
    César Pedroza-Roldán · 2012 · Journal of Bacteriology & Parasitology
  37. Immunoregulation by ESAT-6: From Pathogenesis of Tuberculosis to Potential Anti-Inflammatory and Anti-Rejection Application
    Weihui Lu, Jingru Lin, Yuming He, Bin Yang, Feifei Qiu, Zhenhua Dai · 2025 · Pharmaceuticals
  38. The Role of MicroRNAs in Viral and Bacterial Infections
    Laura Gröger, Eckart U. Meese, Andreas Keller · 2025 · Annual Review of Pathology Mechanisms of Disease
  39. Reply to Levis and Rendini
    Dhiraj Kumar Singh, Ved Prakash Dwivedi, Anand Ranganathan, William R. Bishai, Luc Van Kaer, Gobardhan Das · 2017 · The Journal of Infectious Diseases
  40. Membrane Insertion of Mycobacterium tuberculosis EsxA in Cultured Lung Epithelial Cells
    Qi Zhang, Javier Aguilera, Salvador Vazquez Reyes, Jianjun Sun · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  41. Mycobacterial surface-associated ESX-1 virulence factors play a role in mycobacterial adherence and invasion into lung epithelial cells
    Yanqing Bao, Qi Zhang, Lin Wang, Javier Aguilera, Salvador Vazquez Reyes, Jianjun Sun · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Bergenin potentiates BCG efficacy by enriching mycobacteria-specific adaptive memory responses via the Akt-Foxo-Stat4 axis
    Suparba Mukhopadhyay, Isha Pahuja, Ahmed Abdallah Okieh, Darshana Pandey, Vinod Yadav, Ashima Bhaskar, Ved Prakash Dwivedi · 2024 · Tuberculosis
  43. Immunological Manifestations in Sarcoidosis
    Mirjam Kool, Caroline E. Broos · 2018 · Elsevier eBooks
  44. INDUCTION OF STRONGER AND LONG LASTING VACCINE IMMUNITY TO TUBERCULOSIS
    Pearl Bakhru · 2012 · Digital Commons-TMC (Texas Medical Center)
  45. References
    2021 · Elsevier eBooks
  46. Major Contribution of Myeloid Cells In TB specific Host Gene Signature: Revelations from Re-Analysis of Publicly Available Datasets
    Anuradha Gautam, Saroj Kant Mohapatra, Bhaswati Pandit · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Abstract 2772: The development of immunotherapy agents from the indigenous herbal plants and microbes used by the tantric practitioner of Vedic Jiva Upakara Cikitsha Tantra (Vedic altruism-based medicine system) of Assam, India
    Lekhika Pathak, Tutumoni Baishya, Partha Saikia, Nihar Ranjan Das, Sailen Baishya, Rupam Das, Pragya Dutta, Chayanika Das, Mallika Maral, Gakul Das et al. · 2023 · Cancer Research
  48. A sinalização através do receptor Axl desempenha um papel protetor para o hospedeiro durante a tuberculose experimental
    André Aparecido dos Santos Correa · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  49. Papel de IL-1α na comorbidade obesidade e tuberculose
    Vinícius Bottura Apolloni · 2024 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  50. Limitation of Deleterious iNOS ‐Expressing Interstitial Macrophages Is Dependent on Protective IL ‐1α and IL ‐17 in Tuberculosis and Existing Obesity
    Vinícius Bottura Apolloni, Rômulo Silva de Oliveira, Ualter Guilherme Cipriano, Giseli Furlan Corrêa, Ana Flávia Gembre, Thais Fernanda de Campos Fraga‐Silva, Leandra Náira Zambelli Ramalho, Diego Luís Costa, Vânia Luiza Deperon Bonato · 2025 · Immunology
  51. Additional file 1 of A multiple T cell epitope comprising DNA vaccine boosts the protective efficacy of Bacillus Calmette–Guérin (BCG) against Mycobacterium tuberculosis
    Sudeep K. Maurya, Aqdas, Mohammad, Das, Deepjyoti Kumar, Sanpreet Singh, Nadeem, Sajid, Kaur, Gurpreet, Agrewala, Javed Naim · 2020 · Figshare
  52. Deciphering the immune response to respiratory pathogens - Role of programmed death-ligand 1
    Emmanuel Stephen Victor · 2016 · theses.fr (ABES)
  53. Engineering internally his-tagged ESX secretion system fusion antigens for tuberculosis nanoparticle vaccines
    Wen-Ling Hsu, Yang Jiao, Wei‐Chiao Huang, Kristina N. Tran, Brennen T. Troyer, Matthew G. Hvasta, Brian A. Kuhlman, Andrés Obregón‐Henao, Jonathan F. Lovell · 2026 · Journal of Biological Chemistry