CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature
Swanson, Phillip A., Hart, Geoffrey T., Russo, Matthew V., Nayak, Debasis, Yazew, Takele, Peña, Mirna, Khan, Shahid M., Janse, Chris J. +2 more·2016·PLOS Pathogens
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- CD8+ T cells promote tubule-interstitial damage in malaria-induced acute kidney injuryDouglas Esteves Teixeira¹, Sarah A.S. Alves, Alessandro S. Pinheiro, Leandro S. Silva, Rodrigo Pacheco Silva-Aguiar, Diogo B. Peruchetti, Tatiana Almeida Pádua, Mariana Conceicao de Souza, Celso Caruso‐Neves, Ana Acácia S. Pinheiro · 2025 · Frontiers in Cellular and Infection Microbiology
- IFNγ-inducible Gbp4 and Irgb6 contribute to experimental cerebral malaria pathology in the olfactory bulbJulia Matsuo-Dapaah, Jalal Alshaweesh, Michelle Sue Jann Lee, Tomoya Hayashi, Rashmi Dash, Masafumi Kuroda, Kazuki Tainaka, Manabu Ozawa, Ayumi Kuratani, Masahiro Yamamoto et al. · 2025 · mBio
- Microglia exhibit a dynamic response, modulating inducible nitric oxide synthase expression and the production of pro-inflammatory cytokines during experimental cerebral malariaLucas Freire-Antunes, Uyla Ornellas-Garcia, Marcos Vinícius Rangel-Ferreira, Mônica Lucas Ribeiro-Almeida, Leonardo J. M. Carvalho, Cláudio Tadeu Daniel‐Ribeiro, Flávia Lima Ribeiro-Gomes · 2025 · Frontiers in Immunology
- Activation of the HIF1α Pathway in Neurologic Disease: A Targetable Master Regulator to Reduce NeuropathologyJavonte Thelwell, Aaron J. Johnson · 2026 · Neuroglia
- Human Cerebral Malaria and Experimental Cerebral Malaria in Mice: Relevance and ApplicabilityJayalakshmi Krishnan · 2017 · MOJ Biology and Medicine
- Cerebral malaria: Understanding the parasite pathogenesis in the brainEmílio Telles de Sá Moreira, Hugo Caire Castro-Faria-Neto, Patricia Rodrigues Pinto dos Reis · 2024 · Elsevier eBooks
- Cerebral Malaria: Clinicians, Extracellular Vesicles, and Therapeutically-Rational Exchange (T-REX)Ryan Philip Jajosky, Audrey Nadine Jajosky, Philip G. Jajosky · 2024 · Preprints.org
- Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrierAlina Batzilla, Pia Dernick, Jon Bezney, Andreas R. Gschwind, Fumio Nakaki, Mireia Altadill, Hannah Fleckenstein, Livia Piatti, Sílvia Sanz, Manuel Fiegl et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Malaria: pathology, immune response, and vaccine design: A mini reviewHenry S. Pan, Haley O. Tucker · 2020 · Neurology and Neuroscience
- The Liver-Stage Plasmodium Infection is a Critical Checkpoint for Development of Experimental Cerebral MalariaYuko Sato, Stefanie Ries, Werner Stenzel, Simon Fillatreau, Kai Matuschewski · 2018 · SSRN Electronic Journal
- Studies on the immunological mechanisms leading to protection or pathology during malaria infectionDaniel McGuire · 2019
- Cerebral MalariaPatrícia Reis, Vanessa Estato, Hugo Caire de Castro Faria Neto · 2020
- Cerebral malaria is regulated by host mediated changes in Plasmodium gene expressionClare Kai Cimperman, Mirna Peña, Sohret Meryem Gokcek, Brandon P. Theall, Meha V. Patel, Anisha Sharma, Chen‐Feng Qi, Daniel E. Sturdevant, Louis H. Miller, Patrick L. Collins et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- MalariaJayalakshmi Krishnan · 2023 · BENTHAM SCIENCE PUBLISHERS eBooks
- Cytolytic CD8+ T cell response to SARS-CoV-2 and non-SARS-CoV-2-related viruses is associated with severe manifestation of COVID-19Kristina Allers, Verena Moos, Jörg Hofmann, Mario Witkowski, Hildrun Haibel, Stefan Angermair, Thomas Schneider · 2023 · Clinical Immunology
- Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cellsJacob Hildebrand, Noah R. Daniels, Emma M. Dehm, Benjamin D. Fisher, Joseph K. Guter, Chris J. Janse, Erin D. Lucas, Jules A. Sangala, Trevor N. Tankersley, Geoffrey T. Hart et al. · 2025 · PLoS Pathogens
- Additional file 2 of Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8+ T cells in cerebral malariaYi Wang, Shen, Yan, Liang, Jiao, Wang, Shubiao, Yuxiao Huang, Zhu, Qinghao, Zhang, Xizhi, Kangjie Yu, Tong, Guodong, Chao Yang et al. · 2024 · Figshare
- Additional file 1 of Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8+ T cells in cerebral malariaYi Wang, Yan Shen, Liang, Jiao, Wang, Shubiao, Yuxiao Huang, Zhu, Qinghao, Zhang, Xizhi, Kangjie Yu, Tong, Guodong, Chao Yang et al. · 2024 · Figshare
- Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria modelSha-sha Chen, Qingxin Yang, Yu Zhong, Defu Liu, Lifang Zhou, Han-cheng Wei, Changling Li, Junwei Song, Yu-hang Wang, Xiao Hu et al. · 2026 · mBio
- Etude de la présentation des antigènes du CMH de classe II aux lymphocytes T CD4 au cours du stade sanguin du paludisme chez la sourisMarion Draheim · 2017
- Rôle de la présentation antigénique par les cellules endothéliales de la barrière hémato-encéphalique dans les pathologies inflammatoires affectant le système nerveux centralCéline Meyer · 2018
- Etude de l'impact des infections parasitaires et virales sur les maladies inflammatoires médiées par les lymphocytes TAli Hassan · 2019 · theses.fr (ABES)
- Role of ATP2B4 and human malaria : looking for functional genetic variants associated with malariaSamia Nisar · 2020
- Is the Association of Granzyme B and the Exported Parasite Hsp70 a Possible Trojan Horse of Severe Malaria?Tendamudzimu Harmfree Dongola, Addmore Shonhai · 2026 · Advances in experimental medicine and biology