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Measurements of Plasma Methoxytyramine, Normetanephrine, and Metanephrine as Discriminators of Different Hereditary Forms of Pheochromocytoma
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BACKGROUND: Pheochromocytomas are rare catecholamine-producing tumors derived in more than 30% of cases from mutations in 9 tumor-susceptibility genes identified to date, including von Hippel-Lindau tumor suppressor (VHL); succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB); and succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD). Testing of multiple genes is often undertaken at considerable expense before a mutation is detected. This study assessed whether measurements of plasma metanephrine, normetanephrine, and methoxytyramine, the O-methylated metabolites of catecholamines, might help to distinguish different hereditary forms of the tumor. METHODS: Plasma concentrations of O-methylated metabolites were measured by liquid chromatography with electrochemical detection in 173 patients with pheochromocytoma, including 38 with multiple endocrine neoplasia type 2 (MEN 2), 10 with neurofibromatosis type 1 (NF1), 66 with von Hippel-Lindau (VHL) syndrome, and 59 with mutations of SDHB or SDHD. RESULTS: In contrast to patients with VHL, SDHB, and SDHD mutations, all patients with MEN 2 and NF1 presented with tumors characterized by increased plasma concentrations of metanephrine (indicating epinephrine production). VHL patients usually showed solitary increases in normetanephrine (indicating norepinephrine production), whereas additional or solitary increases in methoxytyramine (indicating dopamine production) characterized 70% of patients with SDHB and SDHD mutations. Patients with NF1 and MEN 2 could be discriminated from those with VHL, SDHB, and SDHD gene mutations in 99% of cases by the combination of normetanephrine and metanephrine. Measurements of plasma methoxytyramine discriminated patients with SDHB and SDHD mutations from those with VHL mutations in an additional 78% of cases. CONCLUSIONS: The distinct patterns of plasma catecholamine O-methylated metabolites in patients with hereditary pheochromocytoma provide an easily used tool to guide cost-effective genotyping of underlying disease-causing mutations.
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“Additionally, measurements of plasma methoxytyramine discriminated patients with SDH mutations from those with VHL mutations in a further 78% of cases (181).”
From Adrenal incidentaloma (2020) · cites this paper as [181]
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“In 1 large study of patients with pheochromocytoma and/or paraganglioma, patients with NF1 and MEN2 mutations could be discriminated from those with VHL and SDH mutations in 99% of cases by the relative concentrations of normetanephrine and metanephrine, as all patients with NF1 and MEN2 presented with tumors characterized by increased plasma concentrations of metanephrine, in contrast to patients”
From Adrenal incidentaloma (2020) · cites this paper as [181]
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Lenders, J. W. M., Eisenhofer, G., Mannelli, M., & Pacák, K. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67139-5 · Cited by 1,541
Self-citationGerm-Line Mutations in Nonsyndromic Pheochromocytoma
Neumann, H. P. H., Bausch, B., McWhinney, S. R., Bender, B., Gimm, O., Franke, G., Schipper, J., Klisch, J., Altehoefer, C., Zerres, K., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020152 · Cited by 1,350
Biochemical Diagnosis of Pheochromocytoma: Which Test Is Best?
Lenders, J. W. M., Pacak, K., Walther, M. M., Linehan, W. M., Mannelli, M., Friberg, P., Keiser, H. R., Goldstein, D. S., & Eisenhofer, G. (2002) · JAMA · doi:10.1001/jama.287.11.1427 · Cited by 1,134
Self-citationGenetic Testing in Pheochromocytoma or Functional Paraganglioma
Amar, L., Bertherat, J. Y., Baudin, É., Ajzenberg, C., Paillerets, B. B., Chabre, O., Chamontin, B., Delemer, B., Giraud, S., Murat, A., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.1484 · Cited by 683
Pheochromocytoma: recommendations for clinical practice from the First International Symposium
Pacák, K., Eisenhofer, G., Ahlman, H., Bornstein, S. R., Gimenez‐Roqueplo, A., Grossman, A. B., Kimura, N., Mannelli, M., McNicol, A. M., & Tischler, A. S. (2007) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0396 · Cited by 675
Self-citationSDHA is a tumor suppressor gene causing paraganglioma
Burnichon, N., Brière, J.-J., Libé, R., Vescovo, L., Rivière, J., Tissier, F., Jouanno, E., Jeunemaı̂tre, X., Bénit, P., Tzagoloff, A., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq206 · Cited by 645
van Nederveen, F. H., Gaal, J., Favier, J., Korpershoek, E., Oldenburg, R. A., de Bruyn, E. M., Sleddens, H. F. B. M., Derkx, P., Rivière, J., Dannenberg, H., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70164-0 · Cited by 554
Self-citationEisenhofer, G., Goldstein, D. S., Stull, R., Keiser, H. R., Sunderland, T., Murphy, D. L., & Kopin, I. J. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.11.2030 · Cited by 477
Self-citationGermline mutations in TMEM127 confer susceptibility to pheochromocytoma
Qin, Y., Yao, L., King, E. E., Buddavarapu, K., Lenci, R. E., Chocron, E. S., Lechleiter, J. D., Sass, M., Aronin, N., Schiavi, F., et al. (2010) · Nature Genetics · doi:10.1038/ng.533 · Cited by 379
Eisenhofer, G., Lenders, J. W. M., Linehan, W. M., Walther, M. M., Goldstein, D. S., & Keiser, H. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906173402404 · Cited by 346
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Amodru, V., Guérin, C., Delcourt, S., Romanet, P., Loundou, A., Viana, B., Brue, T. C., Castinetti, F., Sebag, F. A., Pacák, K., et al. (2017) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-017-3833-y · Cited by 37
Eisenhofer, G., Brown, S., Peitzsch, M., Pelzel, D., Lattke, P., Glöckner, S., Stell, A., Prejbisz, A., Faßnacht, M., Beuschlein, F., et al. (2013) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563213487894 · Cited by 36
Self-citationPheochromocytoma and paraganglioma: germline genetics and hereditary syndromes
Turin, C. G., Crenshaw, M. M., & Fishbein, L. M. (2022) · Endocrine Oncology · doi:10.1530/eo-22-0044 · Cited by 37
Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma
Vícha, A., Taïeb, D., & Pacák, K. (2014) · Endocrine Related Cancer · doi:10.1530/erc-13-0398 · Cited by 35
Krumeich, L. N., Cucchiara, A. J., Nathanson, K. L., Kelz, R. R., Fishbein, L. M., Fraker, D. L., Roses, R. E., Cohen, D. L., & Wachtel, H. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab401 · Cited by 33
Li, S., Ding, Y.-Q., Si, Y.-L., Ye, M., Xu, C., & Qi, X.-P. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.543246 · Cited by 32
Pheochromocytomas are diagnosed incidentally and at older age in neurofibromatosis type 1
Moramarco, J., Ghorayeb, N. E., Dumas, N., Nolet, S., Boulanger, L., Burnichon, N., Lacroix, A., Haffaf, Z. E., Gimenez‐Roqueplo, A., Hamet, P., et al. (2016) · Clinical Endocrinology · doi:10.1111/cen.13265 · Cited by 31
When should genetic testing be performed in patients with neuroendocrine tumours?
O’Shea, T., & Druce, M. R. (2017) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-017-9430-3 · Cited by 31
Connecting Molecular Pathways to Hereditary Cancer Risk Syndromes
Testa, J. R., Malkin, D. M., & Schiffman, J. D. (2013) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbook_am.2013.33.81 · Cited by 29
Grouzmann, E., Matter, M., Bilz, S., Herren, A., Triponez, F., Henzen, C., Kim, K., Zulewski, H., Buclin, T., Brakch, N., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1557 · Cited by 28
Pathophysiology and Diagnosis of Disorders of the Adrenal Medulla: Focus on Pheochromocytoma
Lenders, J. W. M., & Eisenhofer, G. (2014) · Comprehensive physiology · doi:10.1002/cphy.c130034 · Cited by 30
Self-citationGuérin, C., Romanet, P., Taïeb, D., Brue, T. C., Lacroix, A., Sebag, F. A., Barlier, A., & Castinetti, F. (2017) · Endocrine Related Cancer · doi:10.1530/erc-17-0266 · Cited by 27
Huang, X. B., Guo, X., Wang, H., & Zhang, H. (2014) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2014.11.038 · Cited by 26
Mel'nichenko, G., Troshina, E., Bel'tsevich, D., Kuznetsov, N. S., & Yukina, M. (2015) · Endocrine Surgery · doi:10.14341/serg2015315-33 · Cited by 26
Eid, M., Foukal, J., Sochorová, D., Tuček, Š., Starý, K., Kala, Z., Mayer, J., Němeček, R., Trna, J., & Kunovský, L. (2023) · Cancer Medicine · doi:10.1002/cam4.6010 · Cited by 26
Ghosal, S., Vanova, K. H., Uher, O., Das, S., Patel, M. A., Meuter, L., Huynh, T., Jha, A., Talvacchio, S. K., Knue, M., et al. (2022) · Endocrine · doi:10.1007/s12020-022-03218-1 · Cited by 26
Genetic testing in the clinical care of patients with pheochromocytoma and paraganglioma
Rana, H. Q., Rainville, I. R., & Vaidya, A. (2014) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000059 · Cited by 26
Gieldon, L., Masjkur, J. R., Richter, S., Därr, R., Lahera, M., Aust, D. E., Zeugner, S., Rump, A., Hackmann, K., Tzschach, A., et al. (2017) · European Journal of Endocrinology · doi:10.1530/eje-17-0714 · Cited by 24
Self-citationDeutschbein, T., Faßnacht, M., Weismann, D., Reincke, M., Mann, K., & Petersenn, S. (2014) · Clinical Endocrinology · doi:10.1111/cen.12590 · Cited by 24
Kline, G. A., Boyd, J. M., Leung, A. A. C., Tang, A. R., & Sadrzadeh, H. (2020) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2020.01.005 · Cited by 24
Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma
Osinga, T. E., Links, T. P., Dullaart, R. P. F., Pacák, K., van der Horst‐Schrivers, A. N. A., Kerstens, M. N., & Kema, I. P. (2017) · The FASEB Journal · doi:10.1096/fj.201601131r · Cited by 28
Noortman, W. A., Vriens, D., de Geus‐Oei, L., Slump, C. H., Aarntzen, E. H. J. G., van Berkel, A., Timmers, H. J. L. M., & van Velden, F. H. P. (2022) · European Radiology · doi:10.1007/s00330-022-09034-5 · Cited by 22
Self-citationFliedner, S. M. J., Brabant, G. E., & Lehnert, H. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2760-3 · Cited by 22
The clinical genetics of phaeochromocytoma and paraganglioma
Gunawardane, P. T. K., & Grossman, A. B. (2017) · Archives of Endocrinology and Metabolism · doi:10.1590/2359-3997000000299 · Cited by 20
Smith, J. D., Ellsperman, S. E., Basura, G. J., & Else, T. (2021) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.256 · Cited by 20
Osinga, T. E., van den Eijnden, M. H. A., Kema, I. P., Kerstens, M. N., Dullaart, R. P. F., de Jong, W. H. A., Sluiter, W. J., Links, T. P., & van der Horst‐Schrivers, A. N. A. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3418 · Cited by 18
Buffet, A., Calsina, B., Flores, S. K., Giraud, S., Lenglet, M., Romanet, P., Deflorenne, E., Aller, J., Bourdeau, I., Paillerets, B. B., et al. (2020) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2019-106519 · Cited by 20
The Evaluation and Treatment of Endocrine Forms of Hypertension
Velasco, A., & Vongpatanasin, W. (2014) · Current Cardiology Reports · doi:10.1007/s11886-014-0528-x · Cited by 19
Twentyman, J. M., Cradic, K. W., Singh, R., & Grebe, S. K. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2012.186601 · Cited by 19
Self-citationThe NF1 gene: a frequent mutational target in sporadic pheochromocytomas and beyond
Welander, J., Söderkvist, P., & Gimm, O. (2013) · Endocrine Related Cancer · doi:10.1530/erc-13-0046 · Cited by 19
Fliedner, S. M. J., Shankavaram, U. T., Marzouca, G., ELKAHLOUN, A. G., Jochmanová, I., Därr, R., Linehan, W. M., Timmers, H. J. L. M., Tischler, A. S., Papaspyrou, K., et al. (2016) · Neoplasia · doi:10.1016/j.neo.2016.07.008 · Cited by 20
Self-citationPheochromocytoma/Paraganglioma: Is This a Genetic Disorder?
Fishbein, L. M. (2019) · Current Cardiology Reports · doi:10.1007/s11886-019-1184-y · Cited by 19
Raygada, M. J., King, K. S., Adams, K. T., Stratakis, C. A., & Pacák, K. (2014) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2013-0369 · Cited by 20
Self-citationMoraitis, A. G., Martucci, V. L., & Pacák, K. (2014) · Endocrine Practice · doi:10.4158/ep13268.ra · Cited by 17
Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma
Sue, M., Martucci, V. L., Frey, F., Lenders, J. W. M., Timmers, H. J. L. M., Pęczkowska, M., Prejbisz, A., Brede, S., Bornstein, S. R., Arlt, W., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0756 · Cited by 17
Self-citationPET detectives: Molecular imaging for phaeochromocytomas and paragangliomas in the genomics era
Ryder, S. J., Love, A., Duncan, E. L., & Pattison, D. A. (2020) · Clinical Endocrinology · doi:10.1111/cen.14375 · Cited by 18
Radioimmunoassay of Chromogranin A and Free Metanephrines in Diagnosis of Pheochromocytoma
Bílek, R., Zelinka, T., Vlček, P., Duskova, J., Michalský, D., Novák, K., Václavíková, E., & Widimsky, J., Jr. (2017) · Physiological Research · doi:10.33549/physiolres.933719 · Cited by 17
Management of Head and Neck Paragangliomas: A Series of 9 Cases and Review of the Literature
Destito, D., Bucolo, S., Florio, A., & Quattrocchi, C. (2012) · Ear Nose & Throat Journal · doi:10.1177/014556131209100811 · Cited by 16
Gutiérrez, A., Primo, E. N., Eguílaz, M., Parrado, C., Rubianes, M. D., & Rivas, G. A. (2016) · Microchemical Journal · doi:10.1016/j.microc.2016.08.001 · Cited by 16
Liquid chromatography tandem mass spectrometry for plasma metadrenalines
Davies, S. L., & Davison, A. S. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.05.024 · Cited by 16
Precision Medicine in Phaeochromocytoma and Paraganglioma
Winzeler, B. F., Challis, B., & Casey, R. T. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11111239 · Cited by 17
Hereditary and Sporadic Pheochromocytoma: Comparison of Imaging, Clinical, and Laboratory Features
Chung, R., O’Shea, A., Sweeney, A. T., Mercaldo, N. D., McDermott, S., & Blake, M. A. (2022) · American Journal of Roentgenology · doi:10.2214/ajr.21.26918 · Cited by 16
Bima, C., Bioletto, F., Lopez, C., Bollati, M., Arata, S., Procopio, M., Gesmundo, I., Ghigo, E., Maccario, M., & Parasiliti‐Caprino, M. (2022) · Biomedicines · doi:10.3390/biomedicines10081813 · Cited by 15
Choat, H. M., Derrevere, K., Knight, L., Brown, W., & Mack, E. H. (2014) · Case Reports in Endocrinology · doi:10.1155/2014/502734 · Cited by 15
Pheochromocytomas in Multiple Endocrine Neoplasia Type 2
Tsang, V., Tacon, L. J., Learoyd, D., & Robinson, B. G. (2015) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-319-22542-5_7 · Cited by 15
Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use
Tsiomidou, S., Pamporaki, C., Geroula, A., van Baal, L., Weber, F., Dralle, H., Schmid, K. W., Führer, D., & Unger, N. (2022) · Clinical Endocrinology · doi:10.1111/cen.14724 · Cited by 16
Hypoxia signaling pathway: A central mediator in endocrine tumors
Watts, D., Jaykar, M. T., Bechmann, N., & Wielockx, B. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1103075 · Cited by 15
Patin, F., Crinière, L., Francia, T., Kassem, S., Pierre, P. R., Bruno, C., Vayne, C., Vourc’h, P., Bretagne, I. B., Andres, C. R., et al. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.05.008 · Cited by 15
Current Diagnostic Status of Pheochromocytomaand Future Perspective: A Mini Review
Khatami, F., & Tavangar, S. M. (2017) · Iranian journal of pathology · doi:10.30699/ijp.2017.26267 · Cited by 14
Therapies targeting the signal pathways of pheochromocytoma and paraganglioma
Liu, Y., Liu, L., & Zhu, F. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s219056 · Cited by 14
Glycemic disorders in patients with pheochromocytomas and sympathetic paragangliomas
Castro, M. A., Ojeda, C. M., García-Centeno, R., López-García, M.-C., Lamas, C., Hanzu, F. A., Mora, M., Tous, M. D. C., Gómez, P. R. D. V., Ramírez, P. A. P., et al. (2022) · Endocrine Related Cancer · doi:10.1530/erc-22-0218 · Cited by 15
Feocromocitoma-paraganglioma: del diagnóstico bioquímico al genético
Megías, M. C., Rodrı́guez-Puyol, D., Rodríguez, L. F., Sención-Martínez, G., & Miguel, P. M. (2016) · Nefrología · doi:10.1016/j.nefro.2016.03.010 · Cited by 13
Liu, Z., Liu, Q., Deng, Y., Zhao, H., Zeng, J., Zhang, T., Zhang, J., Wang, J., Zhou, W., & Zhang, C. (2021) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-021-03715-8 · Cited by 13
Pereira, B. D., Silva, T., Bernardo, A. T., César, R., Luíz, H. V., Pacák, K., & Mota‐Vieira, L. (2018) · International Journal of Endocrinology · doi:10.1155/2018/8470642 · Cited by 13
Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation
Collins, N., & Dietzek, A. M. (2011) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2011.06.084 · Cited by 12
Genetics of Pheochromocytoma and Paraganglioma
Pereira, B. D., Luíz, H. V., Ferreira, A. G., & Portugal, J. (2019) · Codon Publications eBooks · doi:10.15586/paraganglioma.2019.ch1 · Cited by 12
Dopamine concentration in blood platelets is elevated in patients with head and neck paragangliomas
Osinga, T. E., van der Horst‐Schrivers, A. N. A., van Faassen, M. H. J. R., Kerstens, M. N., Dullaart, R. P. F., Peters, M. A. M., van der Laan, B. F. A. M., de Bock, G. H., Links, T. P., & Kema, I. P. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2015-0631 · Cited by 12
Zhao, B., Zhou, Y., Zhao, Y., Zhao, Y., Wu, X., Bi, Y., Luo, Y., Ji, Z., & Rong, S. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00165 · Cited by 13
Andrade, M. D. O., da Cunha, V. S., de Oliveira, D. C., de Moraes, O. L., & Lofrano‐Porto, A. (2018) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-3997000000033 · Cited by 12
A nomogram for predicting the presence of germline mutations in pheochromocytomas and paragangliomas
Su, T. W., Zhong, X., Ye, L., Song, W., Jiang, L., Xie, J., Jiang, Y., Zhou, W., Zhang, C., Wu, L., et al. (2019) · Endocrine · doi:10.1007/s12020-019-02075-9 · Cited by 12
Eisenhofer, G., Vocke, C. D., ELKAHLOUN, A. G., Huynh, T.-T., Prodanov, T., Lenders, J., Timmers, H. J. L. M., Benhammou, J. N., Linehan, W. M., & Pacák, K. (2012) · Hormone and Metabolic Research · doi:10.1055/s-0032-1304662 · Cited by 11
Self-citationPuliani, G., Sesti, F. F., Feola, T., Leo, N. D., Polti, G., Verrico, M., Modica, R., Colao, A., Lenzi, A., Isidori, A. M., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020588 · Cited by 11
Liu, L., Xie, W., Song, Z., Wang, T., Li, X., Gao, Y., Li, Y., Zhang, J., & Guo, X. (2021) · Clinical Endocrinology · doi:10.1111/cen.14585 · Cited by 10
Tsoli, M., Daskalakis, K., Kassi, E. N., Kaltsas, G., & Tsolakis, A. V. (2021) · Biology · doi:10.3390/biology10070580 · Cited by 10
The RASopathies: Biology, genetics and therapeutic options
Longo, J. F., & Carroll, S. L. (2022) · Advances in cancer research · doi:10.1016/bs.acr.2021.07.007 · Cited by 10
Rajan, S., Zaidi, G., Agarwal, G., Mishra, A., Agarwal, A., Mishra, S. K., & Bhatia, E. (2015) · World Journal of Surgery · doi:10.1007/s00268-015-3255-6 · Cited by 10
Hypertension artérielle d’origine surrénale : reconnaître, évaluer et prendre en charge
Amar, L., Lorthioir, A., Giavarini, A., Plouin, P., & Azizi, M. (2014) · La Presse Médicale · doi:10.1016/j.lpm.2013.06.032 · Cited by 9
When Biochemical Phenotype Predicts Genotype: Pheochromocytoma and Paraganglioma
Yan, Q., Bancos, I., Gruber, L., Bancos, C., McKenzie, T. J., Babovic‐Vuksanovic, D., & Young, W. F. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.01.010 · Cited by 9
Metastatic sympathetic paraganglioma in a patient with loss of the SDHC gene
Rich, T. A., Jackson, M., Román-Gonzaléz, A., Shah, K. B., Cote, G. J., & Jiménez, C. (2015) · Familial Cancer · doi:10.1007/s10689-015-9821-0 · Cited by 9
Pitfalls in Genetic Analysis of Pheochromocytomas/Paragangliomas—Case Report
Canu, L., Rapizzi, E., Zampetti, B., Fucci, R., Nesi, G., Richter, S., Qin, N., Giaché, V., Bergamini, C., Parenti, G., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4453 · Cited by 9
Self-citationFeocromocitoma: experiencia clínica de tres décadas en un estudio multicéntrico
Iglesias, P., Santacruz, E., García-Sancho, P., Marengo, A. P., Guerrero‐Pérez, F., Pian, H. G., Fajardo, C., Villabona, C. M., & Díez, J. J. (2020) · Revista Clínica Española · doi:10.1016/j.rce.2019.12.016 · Cited by 9
Khurana, M. L., Gupta, P., Khadgawat, R., Bal, C., Kumar, G., Sharma, S., & Tandon, N. (2015) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.163183 · Cited by 9
Multiple Endocrine Neoplasia Type 2 and Medullary Thyroid Carcinoma
Tacon, L. J., Learoyd, D., & Robinson, B. G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00149-9 · Cited by 9
Smy, L., Kushnir, M. M., & Frank, E. L. (2021) · Journal of Mass Spectrometry and Advances in the Clinical Lab · doi:10.1016/j.jmsacl.2021.08.001 · Cited by 8
Garrahy, A., Casey, R. T., Wall, D., Bell, M., & O’Shea, P. M. (2015) · International Journal of Clinical Practice · doi:10.1111/ijcp.12612 · Cited by 8
Kline, G. A., & Chin, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803412-5.00005-7 · Cited by 8
Pheochromocytoma: A three-decade clinical experience in a multicenter study
Iglesias, P., Santacruz, E., García-Sancho, P., Marengo, A. P., Guerrero‐Pérez, F., Pian, H. G., Fajardo, C., Villabona, C. M., & Díez, J. J. (2020) · Revista Clínica Española (English Edition) · doi:10.1016/j.rceng.2019.12.011 · Cited by 8
Davidson, D. F., Bradshaw, N., Perry, C. G., Lindsay, R. S., & Freel, E. M. (2012) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/acb.2012.012021 · Cited by 8
Thompson, M. J., Parameswaran, V., & Burgess, J. R. (2018) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/0004563218811865 · Cited by 8
Kamilaris, C. D. C., & Stratakis, C. A. (2018) · HORMONES · doi:10.1007/s42000-018-0072-y · Cited by 7
Wong, C.-L., Fok, C.-K., & Tam, V. H.-K. (2018) · Endocrinology Diabetes and Metabolism Case Reports · doi:10.1530/edm-18-0006 · Cited by 7
Biochemically Silent Pheochromocytoma Presenting with Hypertensive Crisis During Surgery
Gupta, N., Brau, K. L., Sasson, A. R., & Goldner, W. S. (2015) · AACE Clinical Case Reports · doi:10.4158/ep15800.cr · Cited by 7
Sze, C., O’Toole, S. M., Tirador, R., Akker, S. A., Matson, M. B., Perry, L., Druce, M. R., Dekkers, T., Deinum, J., Lenders, J. W. M., et al. (2017) · Hormone and Metabolic Research · doi:10.1055/s-0042-124419 · Cited by 7
Self-citationPheochromocytoma-paraganglioma: Biochemical and genetic diagnosis
Megías, M. C., Rodrı́guez-Puyol, D., Rodríguez, L. F., Sención-Martínez, G., & Miguel, P. M. (2016) · Nefrología (English Edition) · doi:10.1016/j.nefroe.2016.11.002 · Cited by 7
Clinical Predictors of Pseudohypoxia-Type Pheochromocytomas
Baechle, J. J., Smith, P. M., Ortega, C. A., Wang, T. S., Solórzano, C. C., & Kiernan, C. M. (2022) · Annals of Surgical Oncology · doi:10.1245/s10434-022-11419-1 · Cited by 6
Biomarqueurs en endocrinologie
d’Herbomez, M., Bauters, C. C., Cortet‐Rudelli, C., Dewailly, D., Cao, C. D., & Wémeau, J.-L. (2013) · La Presse Médicale · doi:10.1016/j.lpm.2013.11.003 · Cited by 6
Activation of RAS Signalling is Associated with Altered Cell Adhesion in Phaeochromocytoma
Rossitti, H. M., Dutta, R. K., Larsson, C., Ghayee, H. K., Söderkvist, P., & Gimm, O. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218072 · Cited by 6
Paragangliomas in Carney–Stratakis Syndrome
Khurana, A., Mei, L., Faber, A. C., Smith, S. C., & Boikos, S. A. (2019) · Hormone and Metabolic Research · doi:10.1055/a-0918-8340 · Cited by 6
Heritable and Syndromic Pheochromocytoma and Paraganglioma
Kopp, P. A. (2018) · Contemporary Endocrinology · doi:10.1007/978-3-319-77048-2_4 · Cited by 5
Griffin, T. P., Casey, R. T., Wall, D., Bell, M., & O’Shea, P. M. (2016) · Practical Laboratory Medicine · doi:10.1016/j.plabm.2016.05.001 · Cited by 5
Evolving Clinical Presentation and Assessment of Pheochromocytoma: A Review
MERCADO-ASIS, L. B., Siao, R. M., & Amba, N. F. (2017) · Journal of Medicine University of Santo Tomas · doi:10.35460/2546-1621.2017-0050 · Cited by 5
Pacák, K., Timmers, H. J. L. M., & Eisenhofer, G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00110-4 · Cited by 5
Self-citationPheochromocytoma and multiple endocrine neoplasia syndromes
Waguespack, S. G., & Ying, A. K. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-4858-7.00023-8 · Cited by 5
Dahlmann, P., Onkes, M., Kunte, S. C., Auer, M. K., Disko, U., Wang, K., Lottspeich, C., Stüfchen, I., Schweizer, J. R. D. O. L., Mansour, N., et al. (2025) · EJNMMI Reports · doi:10.1186/s41824-025-00275-3 · Cited by 4
Novel Gene Variants in a Nationwide Cohort of Patients with Pheochromocytoma and Paraganglioma
de la Piscina, I. M., Diego, E., Baquero, C., Fernández-Rubio, E., Torre, E. L. M., Rodríguez, M. D. M., de Azua, T. R., Castaño, L. A., Valdés, N., & on behalf of the Collaborative Working Group (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212056 · Cited by 4
Sakai, K., Asano, M., Hamaguchi, M., Taniguchi, H., Ukimura, O., & Fukui, M. (2023) · Clinical Medicine Insights Endocrinology and Diabetes · doi:10.1177/11795514221148556 · Cited by 4
From arterial hypertension complications to von Hippel-Lindau syndrome diagnosis
Kozaczuk, S., & Beń‐Skowronek, I. (2015) · The Italian Journal of Pediatrics/Italian journal of pediatrics · doi:10.1186/s13052-015-0158-y · Cited by 4
Endocrine hypertension: What is new?
Koch, C. A. (2012) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.1016/s1646-3439(12)70010-x · Cited by 4
Données récentes sur l’hypertension endocrine
Al‐Salameh, A., Cohen, R., Chanson, P., & Plouin, P. (2012) · Annales d Endocrinologie · doi:10.1016/s0003-4266(12)70012-4 · Cited by 4
Metabolism and secretion mechanism of catecholamine syndrome and related treatment strategies
Liu, Y., Wang, Y., Zhou, M., Zhang, L., Pang, Y., Wang, C., Xiao, Q., & Liu, L. (2020) · Journal of Xiangya Medicine · doi:10.21037/jxym-20-88 · Cited by 5
Metadata
- Authors
- Eisenhofer, G., Lenders, J. W., Timmers, H., Mannelli, M., Grebe, S. K., Hofbauer, L. C., Bornstein, S. R., Tiebel, O., Adams, K., Bratslavsky, G., Linehan, W. M., & Pacak, K.
- Affiliations
- Technische Universität Dresden (DE)
- Radboud University Nijmegen (NL)
- University of Florence (IT)
- Mayo Clinic (US)
- Institute of Clinical Chemistry and Laboratory Medicine and
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
- National Institutes of Health (US)
- Reproductive and Adult Endocrinology Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD
- Corresponding author
- Eisenhofer, Graeme
- ORCID
- Venue
- Clinical Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-03-01
- Volume
- 57
- Issue
- 3
- Pages
- 411-420
- ISSN
- 0009-9147 (ISSN-L)
- 1530-8561
- PMC
- PMC3164998
- OpenAlex
- W2163960412
- Cited by
- 290
- References
- 35
- Citations by year
- 2025: 6 · 2024: 6 · 2023: 15 · 2022: 16 · 2021: 20 · 2020: 16 · 2019: 16 · 2018: 17 · 2017: 32 · 2016: 19 · 2015: 32 · 2014: 31 · 2013: 27 · 2012: 22
- FWCI
- 30.48
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Clinical Chemistry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Site cant be reached (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- Deutsche Forschungsgesellschaft
- Center for Regenerative Therapies Dresden
- Dresden Tumor Center
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Center for Cancer Research
- National Cancer Institute
- Topics
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Oncology › Neuroendocrine Tumor Research Advances
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Keywords
- pheochromocytoma, familial pheochromocytoma, methoxytyramine, normetanephrine, metanephrine, von Hippel-Lindau disease, SDHB mutation, SDHD mutation, multiple endocrine neoplasia type 2, neurofibromatosis type 1, genotyping, epinephrine, norepinephrine, dopamine
- MeSH terms
- Adrenal Gland Neoplasms, Diagnosis, Differential, Dopamine, Humans, Metanephrine, Neoplastic Syndromes, Hereditary, Normetanephrine, Pheochromocytoma, Retrospective Studies, Biomarkers, Tumor
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