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Zygosity diagnosis in young twins by parental report
Open accessAbstract
This study reports on zygosity determination in twins of childhood age. Parents responded to questionnaire items dealing with twin similarity in physical characteristics and frequency of mistaking one twin for another by parents, relatives and strangers. The accuracy of zygosity diagnosis was evaluated across twins aged 6, 8, and 10 and across parents. In addition, it was examined whether the use of multiple raters and the use of longitudinal data lead to an improvement of zygosity assignment. Complete data on zygosity questions and on genetic markers or blood profiles were available for 618 twin pairs at the age of 6 years. The method used was predictive discriminant analyses. Agreement between zygosity assigned by the replies to the questions and zygosity determined by DNA markers/blood typing was around 93%. The accuracy of assignment remained constant across age and parents. Analyses of data provided by both parents and collected over multiple ages did not result in better prediction of zygosity. Details on the discriminant function are provided.
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Cited by
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Rosenberg, R. E., Law, J. K., Yenokyan, G., McGready, J., Kaufmann, W. E., & Law, P. A. (2009) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2009.98 · Cited by 495
Netherlands Twin Register: From Twins to Twin Families
Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J.-J., Posthuma, D., van Beijsterveldt, T. C. E. M., Hudziak, J. J., Bartels, M., et al. (2006) · Twin Research and Human Genetics · doi:10.1375/183242706779462426 · Cited by 400
Self-citationHeritability of Autistic Traits in the General Population
Hoekstra, R. A., Bartels, M., Verweij, C. J. H., & Boomsma, D. I. (2007) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.161.4.372 · Cited by 320
Self-citationBokhorst, C. L., Bakermans-kranenburg, M. J., Pasco fearon, R. M., Van ijzendoorn, M. H., Fonagy, P., & Schuengel, C. (2003) · Child Development · doi:10.1046/j.1467-8624.2003.00637.x · Cited by 297
Rietveld, M. J. H., Hudziak, J. J., Bartels, M., van Beijsterveldt, C. E. M., & Boomsma, D. I. (2004) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2004.00247.x · Cited by 223
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Metadata
- Authors
- Rietveld, M., van der Valk, J., Bongers, I., Stroet, T., Slagboom, P., & Boomsma, D.
- Venue
- Twin Research (2000)
- Publisher
- Cambridge University Press (CUP)
- Published
- 2000-09-01
- Volume
- 3
- Issue
- 3
- Pages
- 134-141
- ISSN
- 1369-0523 (ISSN-L)
- 0000-0000
- OpenAlex
- W2145817007
- Cited by
- 203
- References
- 0
- FWCI
- 5.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rietveld, M., van der Valk, J., Bongers, I., Stroet, T., Slagboom, P., & Boomsma, D. (2000). Zygosity diagnosis in young twins by parental report. Twin Research (2000). https://doi.org/10.1375/136905200320565409
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