The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Association of Depression and Life-Sustaining Treatment Preferences in Patients With COPD
Abstract
Study objective Depressive symptoms and reduced health-related quality of life are common in patients with severe COPD. Therefore, understanding the association between preferences for life-sustaining treatment and depression or quality of life is important in providing care. No prior studies have examined the effects of depression and quality of life on treatment preferences in this population.Design and patients Cross-sectional study of 101 patients with oxygen-prescribed COPD.Methods Patients completed the St. George's Respiratory Questionnaire, Center for Epidemiologic Studies-Depression survey, and questions regarding their preferences for mechanical ventilation and cardiopulmonary resuscitation if needed to sustain life.Results Median age was 67.4 years, and median FEV1 was 26.3% predicted. Depression was significantly associated with preferences for resuscitation (50% of depressed patients and 23% of patients without depression refused resuscitation; p = 0.007), but was not associated with preferences for mechanical ventilation. Health-related quality of life was not associated with preferences for either resuscitation or mechanical ventilation.Conclusions Clinicians caring for patients with oxygen-prescribed COPD should understand that health-related quality of life does not predict treatment preferences and should not influence clinicians' views of patients' treatment preferences. However, depression does appear to influence patients' treatment decisions for cardiopulmonary resuscitation, and improvement in depressive symptoms should trigger a reassessment of these preferences.
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“Furthermore, depression has been found to have a profound impact on end-of-life decisions because depressed patients more often opt for “do not resuscitate” decisions.58”
From Anxiety and Depression in COPD (2008) · cites this paper as [58]
In the citing paper
“In addition, depression lowers quality of life and decreases adherence to treatment.22,58”
From Anxiety and Depression in COPD (2008) · cites this paper as [58]
Citations
Cites
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Research works printed but not linked: 1
- Stapleton, 2002, Association of quality of life and depression with treatment preferences for CPR and mechanical ventilation in severe COPD [abstract], Am J Respir Crit Care Med, 165, A22
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Anxiety and Depression in COPD
Maurer, J., Rebbapragada, V., Borson, S., Goldstein, R., Kunik, M. E., Yohannes, A. M., & Hanania, N. A. (2008) · Chest · doi:10.1378/chest.08-0342 · Cited by 720
Lanken, P. N., Terry, P. B., DeLisser, H. M., Fahy, B. F., Hansen-Flaschen, J. H., Heffner, J. E., Levy, M. M., Mularski, R. A., Osborne, M. L., Prendergast, T. J., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200605-587st · Cited by 725
Moens, K., Higginson, I. J., Harding, R., Brearley, S. G., Caraceni, A. T., Cohen, J., Costantini, M., Deliëns, L., Francke, A. L., Kaasa, S., et al. (2014) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2013.11.009 · Cited by 444
Definition, epidemiology and natural history of COPD
Viegi, G., Pistelli, F., Sherrill, D. L., Maio, S., Baldacci, S., & Carrozzi, L. (2007) · European Respiratory Journal · doi:10.1183/09031936.00082507 · Cited by 434
Palliative and end-of-life care for patients with severe COPD
Curtis, J. R. (2007) · European Respiratory Journal · doi:10.1183/09031936.00126107 · Cited by 287
Self-citation
Metadata
- Authors
- Stapleton, R. D., Nielsen, E. L., Engelberg, R. A., Patrick, D. L., & Curtis, J. R.
- Affiliations
- University of Washington (US)
- Corresponding author
- Stapleton, Renee D.
- Venue
- Chest
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 127
- Issue
- 1
- Pages
- 328-334
- ISSN
- 0012-3692 (ISSN-L)
- OpenAlex
- W2154886013
- Cited by
- 121
- References
- 36
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2020: 2 · 2019: 6 · 2018: 5 · 2017: 5 · 2016: 6 · 2015: 4 · 2014: 5 · 2013: 4 · 2012: 9
- FWCI
- 13.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- CHEST Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- depression, chronic obstructive pulmonary disease, life-sustaining treatment preferences, cardiopulmonary resuscitation, mechanical ventilation, health-related quality of life, end-of-life decisions, oxygen therapy
- MeSH terms
- Aged, Cross-Sectional Studies, Depression, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Respiration, Artificial, Comorbidity, Logistic Models, Cardiopulmonary Resuscitation, Pulmonary Disease, Chronic Obstructive
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