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A KETO-MEDIET APPROACH WITH COCONUT SUBSTITUTION AND EXERCISE MAY DELAY THE ONSET OF ALZHEIMER’S DISEASE AMONG MIDDLE-AGED
Abstract
Background: Coconut oil has been widely used to improve health because there is much information available by word of mouth, in books, and on the internet. However, researchers still continue to search for the best diets to improve the quality of life, especially for people with cognitive decline. Objectives: The aim of this review is to develop a novel dietary approach, the Keto-Mediet, which may help prevent the onset of Alzheimer’s disease. Methods: Evidence gained through literature review from 1982 to 2015 on gene-by-diet interaction and lipid and glucose metabolism in the brains of Alzheimer’s patients is converted into the new Keto-Mediet approach. Design: The Keto-Mediet approach combines the benefits of a Ketogenic diet and a Mediterranean diet into a pyramidal model that is rich in various types of vitamins and substitutes coconuts for saturated animal fats. Limited glucose intake is intended to delay brain degeneration. A revised adult food pyramid was created to illustrate the principles of the Keto-Mediet approach. Conclusion: The Keto-Mediet approach represents and interprets food groups according to the revised adult food pyramid. This approach also encourages adherence to this healthy diet and lifestyle changes including exercise for people whose age ranges from 40 to 75 years. Those who comply with this approach will significantly enhance their knowledge and adopt a healthier lifestyle, as compared to those whose modern eating patterns are typically less healthy. Therefore, the Keto-Mediet approach can be applied in hopes of preventing and decreasing Alzheimer’s disease in different ethnicities and cultural groups.
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“Animal studies have shown that VCO can enhance calcium absorption and reduce bone loss, potentially benefiting individuals with osteoporosis.”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [155]
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Ajibola, O. O. (2025) · Discover Food · doi:10.1007/s44187-025-00746-3 · Cited by 6
“This effect is linked to its antioxidant capacity and ability to modulate bone metabolism [155].”
Metadata
- Authors
- Perng, B. C., Chen, M., Perng, J. C., & Jambazian, P.
- Affiliations
- California State University Los Angeles (US)
- Venue
- The Journal of Prevention of Alzheimer's Disease
- Publisher
- Elsevier BV
- Published
- 2016
- Volume
- 4
- Issue
- 1
- Pages
- 1-7
- ISSN
- 2274-5807 (ISSN-L)
- OpenAlex
- W2561576407
- Cited by
- 8
- References
- 0
- Citations by year
- 2025: 2 · 2024: 1 · 2021: 3 · 2020: 1 · 2019: 1
- FWCI
- 0.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Prevention of Alzheimer s Disease (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Food Science › Coconut Research and Applications
- Keywords
- Alzheimer's disease prevention, ketogenic diet, Mediterranean diet, saturated fat, dietary intervention, physical activity, cognitive decline, gene-diet interaction, brain lipid metabolism, glucose metabolism, food pyramid, middle-aged adults, lifestyle modification
- MeSH terms
- Healthy Lifestyle, Adult, Aged, Alzheimer Disease, Cocos, Exercise Therapy, Humans, Middle Aged, Diet, Mediterranean, Diet, Ketogenic
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- CoChat. (2026). Citation check: A KETO-MEDIET APPROACH WITH COCONUT SUBSTITUTION AND EXERCISE MAY DELAY THE ONSET OF ALZHEIMER’S DISEASE AMONG MIDDLE-AGED. https://app.cochat.ai/papers/10.14283/jpad.2016.104
- The paper
- Perng, B. C., Chen, M., Perng, J. C., & Jambazian, P. (2016). A KETO-MEDIET APPROACH WITH COCONUT SUBSTITUTION AND EXERCISE MAY DELAY THE ONSET OF ALZHEIMER’S DISEASE AMONG MIDDLE-AGED. The Journal of Prevention of Alzheimer's Disease. https://doi.org/10.14283/jpad.2016.104