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Cited by 49Nasal Surgery and Airway StudiesSinusitis and nasal conditionsAllergic Rhinitis and Sensitization

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Riduzione volumetrica dei turbinati inferiori con radiofrequenze: risultati clinici a lungo termine

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De Corso, E., Bastanza, G., Di Donfrancesco, V., Guidi, M.L., Morelli Sbarra, G., Passali, G., Poscia, A., de Waure, C., Paludetti, G., Galli, J.·2016·Acta Otorhinolaryngologica Italica
DOI 10.14639/0392-100x-964PMC PMC4977007
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Abstract

Lo scopo del nostro studio è stato quello di valutare i risultati a lungo termine della procedura di riduzione volumetrica dei turbinati inferiori mediante radiofrequenze (RVTR). Abbiamo eseguito una valutazione prospettica longitudinale a lungo termine di 305 pazienti affetti da rinite (114 allergici e 191 non allergici) refrattari alla terapia medica e sottoposti a intervento di RVTR (gennaio 2004 - dicembre 2010). I pazienti sono stati seguiti per un Follow-up medio di 39,70±19,41 mesi (minimo-24, massimo-60 mesi) e sono stati valutati mediante la somministrazione del questionario NOSE-scale prima e dopo l’intervento a distanza di un mese e successivamente ogni anno per 5 anni. I pazienti sono stati considerati affetti da recidiva durante il periodo di follow-up in caso di ricomparsa dei sintomi con un aumento del punteggio totale del NOSE scale di almeno il 75% e necessità di riassumere trattamenti medici. La ricorrenza è stata valutata mediante analisi di sopravvivenza con il metodo di Kaplan-Meyer. Complessivamente abbiamo documentato una buona soddisfazione dei pazienti per quanto riguarda la procedura, con un elevato controllo del dolore e poche complicanze. Nel post-operatorio abbiamo avuto un significativo miglioramento di ostruzione nasale e respirazione orale vicariante (p < 0,05). Dopo 36 mesi abbiamo osservato un peggioramento dei sintomi, in particolare, dopo 36 mesi con un progressivo crescente tasso di recidive significativamente più elevato nei pazienti allergici rispetto a quelli non-allergici (p < 0,05). Abbiamo anche osservato una leggera diminuizione della soddisfazione generale dei pazienti. Il nostro studio conferma la buona tollerabilità da parte dei pazienti della procedura di decongestione dei turbinati inferiori con radiofrequenze con un basso rischio di complicanze. I nostri dati confermano inoltre una buona efficacia a lungo termine nella maggior parte dei pazienti per almeno 36 mesi dopo l’intervento con una probabilità di rimanere liberi da recidiva in questo periodo sempre superiore a 0,8. Nei mesi successivi si assiste a una progressiva riduzione del beneficio clinico in particolare nei pazienti allergici, con una differenza statisticamente significativa rispetto ai pazienti non allergici (p < 0,05).

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Figures

Fig. 1. The figure shows differences respect to baseline of NOSE scale scores items comparing time 0 (PRE intervention) and time 1 values (4 week POST intervention). (1) Nose obstruction and stuffiness. (2) Nose blockage or obstruction. (3) Trouble breathing through my nose or mouth breathing. (4) Trouble sleeping. (5) Unable to get enough air through my nose during exercise or exertion.
Fig. 1. The figure shows differences respect to baseline of NOSE scale scores items comparing time 0 (PRE intervention) and time 1 values (4 week POST intervention). (1) Nose obstruction and stuffiness. (2) Nose blockage or obstruction. (3) Trouble breathing through my nose or mouth breathing. (4) Trouble sleeping. (5) Unable to get enough air through my nose during exercise or exertion.CC BY-NC-ND · PubMed Central
Fig. 2. Temporal trend of the benefit obtained with surgery considering evolution during long-term follow-up of mean NOSE scores for items that significantly improved after surgery.
Fig. 2. Temporal trend of the benefit obtained with surgery considering evolution during long-term follow-up of mean NOSE scores for items that significantly improved after surgery.CC BY-NC-ND · PubMed Central
Fig. 3. Temporal trend of global patient satisfaction evaluated during longterm follow-up by the VAS score (range 0-10). The indicator represents the mean VAS scores about global satisfaction at each follow-up visit.
Fig. 3. Temporal trend of global patient satisfaction evaluated during longterm follow-up by the VAS score (range 0-10). The indicator represents the mean VAS scores about global satisfaction at each follow-up visit.CC BY-NC-ND · PubMed Central
Fig. 4. Estimation of recurrence over time by Kaplan-Meier analysis in all 305 patients enrolled.
Fig. 4. Estimation of recurrence over time by Kaplan-Meier analysis in all 305 patients enrolled.CC BY-NC-ND · PubMed Central
Fig. 5. Estimation of relapse over time by Kaplan-Meier analysis in allergic patients (n = 114) and non-allergic patients (n = 191). The difference between curves was significant by log rank test.
Fig. 5. Estimation of relapse over time by Kaplan-Meier analysis in allergic patients (n = 114) and non-allergic patients (n = 191). The difference between curves was significant by log rank test.CC BY-NC-ND · PubMed Central

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Citations

Cites

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Research works printed but not linked: 34

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Metadata

Authors
De Corso, E., Bastanza, G., Di Donfrancesco, V., Guidi, M. L., Morelli Sbarra, G., Passali, G., Poscia, A., de Waure, C., Paludetti, G., & Galli, J.
Affiliations
  • Department of Head and Neck Surgery - Otorhinolaryngology, Catholic University of the Sacred Heart Rome, Italy;
  • Università Cattolica del Sacro Cuore (IT)
  • Department of Intensive Care and Anesthesiology, Catholic University School of Medicine and Surgery, Rome, Italy;
ORCID
Venue
Acta Otorhinolaryngologica Italica
Publisher
Pacini Editore
Published
2016-05
Volume
36
Issue
3
Pages
199-205
ISSN
  • 0392-100X (ISSN-L)
  • 1827-675X
DOI
10.14639/0392-100x-964
PMC
PMC4977007
OpenAlex
W2398908475
Cited by
49
References
1
Citations by year
2026: 6 · 2025: 4 · 2024: 1 · 2023: 7 · 2022: 11 · 2021: 6 · 2020: 3 · 2019: 2 · 2018: 6 · 2017: 3
FWCI
4.06
Type
journal article
Language
it
Open access
Locations
  • Acta Otorhinolaryngologica Italica (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
  • Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
  • Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
Keywords
inferior turbinate reduction, refractory rhinitis, allergic rhinitis, nasal obstruction, nasal patency, recurrence, long-term outcomes, NOSE scale, patient satisfaction, postoperative complications, mouth breathing, turbinate hypertrophy, radiofrequency ablation
MeSH terms
Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Rhinitis, Otorhinolaryngologic Surgical Procedures, Time Factors, Turbinates, Treatment Outcome, Ablation Techniques, Young Adult

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