Development of the instrument to assess the credibility of effect modification analyses (ICEMAN) in randomized controlled trials and meta-analyses

Schandelmaier, Stefan, Briel, Matthias, Varadhan, Ravi, Schmid, Christopher H., Devasenapathy, Niveditha, Hayward, Rodney A., Gagnier, Joel, Borenstein, Michael +8 more·2020·Canadian Medical Association Journal

DOI 10.1503/cmaj.200077

Cited by (749)

Items 301–400 of 749

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Methods for Integrating Trials and Non-experimental Data to Examine Treatment Effect Heterogeneity
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Risk of kidney and liver diseases after COVID‐19 infection: A systematic review and meta‐analysis
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Subgroup analyses and heterogeneity of treatment effects in randomized trials: a primer for the clinician
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Systematic review and meta-analysis of the safety of chloroquine and hydroxychloroquine from randomized controlled trials on malarial and non-malarial conditions
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Evidence-based Urology: Subgroup Analysis in Randomized Controlled Trials
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Effects of the informed health choices secondary school intervention after 1 year: a prospective meta-analysis using individual participant data
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Anemia Acuity Effect on Transfusion Strategies in Acute Myocardial Infarction
François Martin Carrier, Howard A. Cooper, Gerard Portela, Marnie H. Bertolet, Gilles Lemesle, Micah T. Prochaska, Sarang Kim, John Hunter Alexander, Ian Crozier, Grégory Ducrocq et al. · 2024 · JAMA Network Open
Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac arrest
Omar Dewidar, Audrey L Blewer, Marina Del Rios, Laurie J. Morrison · 2025 · Resuscitation
Matching-Adjusted Indirect Comparison Studies in Oncology: A Scoping Review Focused on Reporting Quality
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Not Closing Compared With Closing the Endometrial Layer During Cesarean Delivery
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REVISE: re-evaluating the inhibition of stress erosions in the ICU—statistical analysis plan for a randomized trial
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The Aging, Community and Health Research Unit Community Partnership Program (ACHRU-CPP) for older adults with diabetes and multiple chronic conditions: study protocol for a randomized controlled trial
J. Ploeg, M. Markle-Reid, R. Valaitis, Kathryn Fisher, Rebecca Ganann, Johanne Blais, Tracey Chambers, Robyn Connors, Andrea Gruneir, F. Légaré et al. · 2022 · BMC Geriatrics
Lessening Organ Dysfunction With Vitamin C (LOVIT) Trial: Statistical Analysis Plan
Neill K. J. Adhikari, Ruxandra L Pinto, Andrew G. Day, Marie-Hélène Masse, Julie Ménard, Sheila Sprague, Djillali Annane, Yaseen M. Arabi, Marie‐Claude Battista, Dian Cohen et al. · 2022 · JMIR Research Protocols
Effects of inulin-type fructans supplementation on cardiovascular disease risk factors: a protocol for a systematic review and meta-analysis of randomised controlled trials
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MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial
Perrine Janiaud, Chiara Zecca, Anke Salmen, Pascal Benkert, Sabine Schädelin, Annette Orleth, Lilian Demuth, Aleksandra Maleska Maceski, Cristina Granziera, Johanna Oechtering et al. · 2024 · Trials
Effects of acupuncture on ischemic stroke: A systematic review with meta-analyses and trial sequential analyses
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The FRIENDS preventive programme for reducing anxiety symptoms in children and adolescents: A systematic review and meta-analysis
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Superficial Parasternal Intercostal Plane Block for Analgesia After Cardiac Surgery: An Updated Meta-analysis of Randomized Controlled Trials With Meta-regression and Trial Sequential Analysis
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Honghao Lai, Gihad E. NESRALLAH, Gordon H Guyatt, Robin W.M. Vernooij, Jiayi Liu, Weilong Zhao, Liangying Hou, Bei Pan, Jiajie Huang, Norm R. C. Campbell et al. · 2026 · BMC Medicine
Anti-epithelial-derived cytokines for severe asthma: Systematic review and meta-analysis
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Nonlinear effects and effect modification at the participant-level in IPD meta-analysis part 2: methodological guidance is available
Nadine Marlin, Peter John Godolphin, Richard Hooper, Richard D Riley, Ewelina Rogozińska · 2023 · Journal of Clinical Epidemiology
An overview of statistical methods for biomarkers relevant to early clinical development of cancer immunotherapies
David Dejardin, Anton Kraxner, Emilie Schindler, Nicolas Städler, Marcel Wolbers · 2024 · Frontiers in Immunology
Modern trials are most useful when they are pragmatic and explanatory – there is no continuum
Perrine Janiaud, Lars G. Hemkens · 2024 · Journal of Clinical Epidemiology
The Diagnostic Accuracy of Serum Procalcitonin for Sepsis in Adult Patients in the Emergency Department
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Effect of bortezomib on the treatment of multiple myeloma: a systematic review protocol
Lucas Oliveira Cantadori, Rafael Dezen Gaiolla, Vânia dos Santos Nunes Nogueira · 2022 · BMJ Open
metaCOVID : A web‐application for living meta‐analyses of COVID ‐19 trials
Theodoros Evrenoglou, Isabelle Boutron, Georgios Seitidis, Lina Ghosn, Anna Chaimani · 2023 · Research Synthesis Methods
Effectiveness and Safety of Non-Invasive Neuromodulation for Vision Restoration: A Systematic Review and Meta-Analysis
Paula Alejandra Navarro, William Omar Contreras López, Alejandro Tello, P.L. Cárdenas, Marcos David Vargas, Luz Catherine Martinez Malo, Juan José Yepes-Núñez · 2023 · Neuro-Ophthalmology
Are novel glucose‐lowering agents' cardiorenal benefits generalizable to individuals of Black race? A meta‐trial sequential analysis to address disparities in cardiovascular and renal outcome trials enrolment
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Universal irradiation of platelets: Does irradiation affect the quality, effectiveness, and safety of platelets for transfusion?
Lorna Cain, Louise J. Geneen, Michael D. Wiltshire, Catherine Kimber, S. Proffitt, Josie Sandercock, Carolyn J. Doree, Susan J Brunskill, Lise J Estcourt · 2024 · Transfusion Medicine Reviews
Tacrolimus versus cyclosporine immunosuppression in lung transplantation: a systematic review and meta-analysis
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Acupuncture for the Management of Chronic Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lei Lan, Li Wang, Behnam Sadeghirad, Juan Tang, Yunyu Liu, Rachel Couban, Wenbin Ma, Jason Walter Busse · 2025 · Current Pain and Headache Reports
Secondary malignancies after treatment of testicular germ cell tumors: a systematic review and meta-analysis
Ahmad Mousa, Ali Amiri, Sanchit Kaushal, Emma Wilson, Viranda H. Jayalath, David‐Dan Nguyen, Isabelle Tan, Robert James Hamilton · 2025 · JNCI Journal of the National Cancer Institute
Low-intensity shockwave therapy for erectile dysfunction
Onuralp Ergun, Kwangmin Kim, Myung Ha Kim, Eu Chang Hwang, Yooni A. Blair, Ahmet Güdeloğlu, Sijo Joseph Parekattil, Philipp Dahm · 2025 · Cochrane Database of Systematic Reviews
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Non-invasive respiratory support in pediatric patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis of randomized controlled trials
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Pharmacologic Modulation of Circadian Rhythms for Delirium Prevention: An Age‐Stratified Systematic Review and Meta‐Analysis
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Matthew J. Summers, Julia L.M. Bels, Amalia Karahalios, Rukshala Kavindi Gunaratne, Jeffrey Presneill, Mark Philip Plummer, Zheng‐Yii Lee, Daren Keith Heyland, Dieter Mesotten, Christian Stoppe et al. · 2026 · Clinical Nutrition
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Digital devices for tuberculosis treatment adherence
Gabriele Vilyte, Tilly Fox, Anke C. Rohwer, Jimmy A Volmink, Michael McCaul · 2023 · Cochrane Database of Systematic Reviews
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Jim M Smit, Philip A. van der Zee, Sara C. M. Stoof, Michel Egide van Genderen, Dominic Snijders, Wim G. Boersma, P. Confalonieri, Francesco Salton, Marco Confalonieri, M-C. Shih et al. · 2023 · medRxiv
Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials
Taji Heravi, Ala, Gryaznov, Dmitry, Schandelmaier, Stefan, Kasenda, Benjamin, Briel, Matthias, Adherence to SPIRIT Recommendations (ASPIRE) Study Group, von Niederhäusern, Belinda, Speich, Benjamin, Ojeda-Ruiz, Elena, Blümle, Anette et al. · 2021 · JAMA Network Open
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The credibility of subgroup analyses reported in stroke trials is low: A systematic review
Ayoola Ademola, Lehana Thabane, Joel Adekanye, Ayooluwanimi Okikiolu, Samuel Babatunde, Mohammed Almekhlafi, Bijoy K. Menon, Michael D. Hill, Kevin A. Hildebrand, Tolulope T. Sajobi · 2023 · International Journal of Stroke
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Neil Corrigan, Julia M. Brown, Richard Emsley, David George Jayne, Rebecca E. A. Walwyn · 2023 · Trials
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Maryam Ghadimi, Reed Alexander Cunningham Siemieniuk, Mark B Loeb, João Pedro Lima, Danial Aminaei, Huda A. Gomaa, Ying Wang, Afeez Abiola Hazzan, John Basmaji, Liang Yao et al. · 2025 · Clinical Microbiology and Infection
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WHO COVID-19 therapeutic guidelines
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Health Equity in Systematic Reviews: A Tutorial—Part 2 Implementing Health Equity Throughout Your Methods
Jennifer Petkovic, Jordi Pardo Pardo, Vivian Andrea Welch, Omar Dewidar, Lara J. Maxwell, Andrea J. Darzi, Tamara Lotfi, Lawrence C. E. Mbuagbaw, Kevin C Pottie, Peter Tugwell · 2025 · Cochrane Evidence Synthesis and Methods
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Efficacy of Antiinflammatory Therapies for Adults With Non-Cystic Fibrosis Bronchiectasis
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