Thyroid-specific transcription factors
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TSH binding to TSHR activates signal transduction pathways that regulate TTF activities, which in turn control expression of thyroid-specific functional proteins including NIS, pendrin, TG, TPO, DUOX(A)1/2, DIO1 and DIO2, participating in TH synthesis and secretion.
“Binding of TSH to TSHR activates signal transduction pathways that regulate TTF activities, which in turn control the gene expression of many thyroid-specific functional proteins, including NIS, pendrin, TG, TPO, DUOX(A)1/2, DIO1 and DIO2, that participate in the synthesis and secretion of THs (158, 159).”
From Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion (2022) · cites this paper as [158]
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Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion
Jing, L., & Zhang, Q. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.992883 · Cited by 61 · see citing works
- Authors
- KAMBE, F., & SEO, H.
- Affiliations
- Research Institute of Environmental Medicine, Nagoya University (JP)
- Venue
- Endocrine Journal
- Publisher
- Japan Endocrine Society
- Published
- 1997
- Volume
- 44
- Issue
- 6
- Pages
- 775-784
- ISSN
- 0918-8959 (ISSN-L)
- 1348-4540
- OpenAlex
- W2049480843
- Cited by
- 36
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 1 · 2016: 2 · 2012: 2
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Endocrine Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- thyroid development, thyroid differentiation, transcriptional regulation, thyroid hormone signaling
- MeSH terms
- PAX8 Transcription Factor, Thyroid Nuclear Factor 1, Animals, Cloning, Molecular, DNA-Binding Proteins, Embryonic and Fetal Development, Gene Expression Regulation, Humans, Nuclear Proteins, Protein Processing, Post-Translational, Thyroid Gland, Transcription Factors, Trans-Activators, Paired Box Transcription Factors
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