Point-of-care testing performed by healthcare professionals outside the hospital setting: consensus based recommendations from the IFCC Committee on Point-of-Care Testing (IFCC C-POCT)
Open accessAbstract
The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Committee on Point-of-Care Testing (C-POCT) supports the use of point-of-care testing (POCT) outside of the hospital setting performed by healthcare professionals without formal laboratory education because of its numerous benefits. However, these benefits are associated with risks that must be managed, to ensure the provision of reliable test results and minimize harm to the patient. Healthcare professionals, local regulatory bodies, accredited laboratories as well as manufacturers should actively be engaged in education, oversight and advice to ensure that the healthcare professional selects the appropriate equipment and is able to analyze, troubleshoot and correctly interpret the point-of-care (POC) test results.
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In decentralized settings, several additional factors may contribute to reduced accuracy, including operator training, sample collection technique, time from sampling to analysis, ambient environmental conditions, and adherence to device-specific quality control protocols.
“In decentralized settings, several additional factors may contribute to reduced accuracy, including operator training, sample collection technique, time from sampling to analysis, ambient environmental conditions (including temperature and humidity), and adherence to device-specific quality control protocols (13).”
From Comparison of point‑of‑care HbA1c devices with laboratory HPLC methods: A systematic review and meta‑analysis (2026) · cites this paper as [13]
The quality-management passage (section 4; page unavailable) calls for operator training and monitoring temperature and humidity during storage, while sections 4.1 and 5 address quality control and sample-collection competency as safeguards for reliable results. The copy does not identify time from sampling to analysis as a factor reducing accuracy, and its temperature-and-humidity recommendation concerns storage rather than ambient conditions during testing. (LLM, conf=0.85)
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Research works printed but not linked: 14
- Kost GJ, Ehrmeyer SS, Chernow B, Winkelman JW, Zaloga GP, Dellinger RP, et al. The laboratory-clinical interface: point-of-care testing. Chest 1999;115:1140-54.
- St John A. The evidence to support point-of-care. Clin Biochem Rev 2010; 31:111-9.
- Lingervelder D, Koffijberg H, Emery JD, Fennessy P, Price CP, van Marwijk H, et al. How to realize the benefits of point-of-care testing at the general practice: a comparison of four high-income countries. Int J Health Policy Manag 2022;11:2248-60.
- Stavelin A, Sandberg S. Harmonization activities of Noklus -a quality improvement organization for point-of-care laboratory examinations. Clin Chem Lab Med 2018;57:106-14.
- Bukve T, Stavelin A, Sandberg S. Effect of participating in a quality improvement system over time for point-of-care C-reactive protein, glucose, and hemoglobin testing. Clin Chem 2016;62:1474-81.
- Sandberg S, Fraser CG, Horvath AR, Jansen R, Jones G, Oosterhuis W, et al. Defining analytical performance specifications: consensus statement from the 1st strategic conference of the European federation of clinical chemistry and laboratory medicine. Clin Chem Lab Med 2015;3:833-5.
- Khan AI. Quality requirements for point of care testing when traditional systems fail. In: Kost GJ, Curtis CM, editors. Global point of care: strategies for disasters, emergencies, and public health resilience. Washington (DC): AACC Press; 2015:3-10 pp.
- Kost GJ. Geospatial hotspots need point-of-care strategies to stop highly infectious outbreaks. Arch Pathol Lab Med 2020;144:1166-90.
- Price CP, Smith I, Van den Bruel A. Improving the quality of point-of- care testing. Fam Pract 2018;35:358-64.
- Gidske G, Sandberg S, Fossum AL, Binder S, Langsjøen EC, Solsvik AE, et al. Point-of-care testing in primary healthcare: a scoring system to determine the frequency of performing internal quality control. Clin Chem Lab Med 2022;60:740-7.
- Khan AI, Khan M, Tirimacco R. Catering for the point-of-care testing explosion. EJIFCC 2021;32:244-54.
- Clinical and Laboratory Standards Institute (CLSI). Risk management techniques to identify and control laboratory error sources. Approved guideline -second edition. CLSI document EP18-A2. Wayne, PA: Clinical and Laboratory Standards Institute; 2009.
- Clinical and Laboratory Standards Institute (CLSI). Point-of-care cnnectivity. Approved standard -second edition. CLSI document POCT01-A2. Wayne, PA: Clinical and Laboratory Standards Institute; 2006.
- Clinical and Laboratory Standards Institute (CLSI). Information technology security of in vitro diagnostic instruments and software systems; approved standard-second edition. CLSI document AUTO11-A2. Wayne, PA: Clinical Laboratory Standards Institute; 2014.
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Kost, G. J., Füzéry, A. K., Caratao, L. K. R., Tinsay, S., Zadran, A., & Ybañez, A. P. (2023) · International Journal of Health Geographics · doi:10.1186/s12942-023-00359-y · Cited by 8 · see citing works
Self-citationWei, Y., Gu, M., Ren, Y., & Hu, Z. (2026) · Biomedical Reports · doi:10.3892/br.2026.2120 · Cited by 3 · see citing works
“…several additional factors may contribute to reduced accuracy, including operator training, sample collection technique, time from sampling to analysis, ambient environmental condi‑ tions (including temperature and humidity), and adherence to device‑specific quality control protocols (13).”
- Authors
- Khan, A. I., Pratumvinit, B., Jacobs, E., Kost, G. J., Kary, H., Balla, J., Shaw, J., Milevoj Kopcinovic, L., Vaubourdolle, M., Oliver, P., Jarvis, P. R. E., Pamidi, P., Erasmus, R. T., O’Kelly, R., Musaad, S., & Sandberg, S.
- Affiliations
- Temple University (US)
- Siriraj Hospital (TH)
- EJ Consulting LLC , Newark , USA
- University of California, Davis (US)
- King Faisal Specialist Hospital & Research Centre (SA)
- Klinicka biochemia a imunochemia , Analyticko-diagnosticke laboratorium, s.r.o. Presov , Slovakia
- University of Ottawa (CA)
- Department of Clinical Chemistry, Sestre Milosrdnice University Hospital Center , Zagreb , Croatia
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospital Universitario La Paz (ES)
- New Medical Sensors , Abbott Laboratories , Alameda , CA , USA
- Werfen (United States) (US)
- Stellenbosch University (ZA)
- Association of Clinical Biochemists in Ireland , Dublin , Ireland
- Waitemata District Health Board (NZ)
- Haraldsplass Diakonale Sykehus (NO)
- Corresponding author
- Khan, Adil I.
- ORCID
- Venue
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Publisher
- Walter de Gruyter GmbH
- Published
- 2023-06-02
- Volume
- 61
- Issue
- 9
- Pages
- 1572-1579
- ISSN
- 1434-6621 (ISSN-L)
- 1437-4331
- OpenAlex
- W4379113663
- Cited by
- 33
- References
- 0
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 12 · 2023: 3
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Chemistry and Laboratory Medicine (CCLM) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Health Sciences › Health Professions › Health Information Management › Healthcare Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Keywords
- point-of-care testing, patient safety, test reliability, regulatory oversight, IFCC recommendations
- MeSH terms
- Point-of-Care Testing, Delivery of Health Care, Hospitals, Humans, Laboratories, Point-of-Care Systems, Consensus
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