The DOI matches its Crossref record.
Ultrasound-Mediated Cavitation of Magnetic Nanoparticles for Drug Delivery Applications
Open accessAbstract
Magnetic nanoparticles guided by an external magnetic field can be used to deliver drugs (e.g., chemotherapeutics) to malignant regions (e.g., tumor tissue). Some nonmagnetic, sonosensitive nanoparticles are known to generate cavitation induced by focused ultrasound. This can can be used to monitor spatial/temporal particle distribution and to stimulate local drug release in target regions. Little to nothing is known about the sonosensitivity of magnetic nanoparticles. Therefore, we investigated this physical phenomenon in the present contribution. We showed that certain magnetic nanoparticles have high cavitation potential and are promising for further research in this regard.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 8
- R. Tietze, S. Lyer, S. Duerr, T.Struffert, T. Engelhorn, et al. Efficient Drug-Delivery Using Magnetic Nanoparticles - Biodistribution and Therapeutic Effects in Tumour Bearing Rabbits, Nanomedicine vol. 9(7): 961-971, 2013.
- S. Lyer, R. Tietze, H. Unterweger, J. Zaloga, R. Singh, J. Matuszak, M. Poettler, RP. Friedrich, S. Duerr, I. Cicha, C. Janko, C. Alexiou. Nanomedical innovation: the SEON- concept for an improved cancer therapy with magnetic nanoparticles. Nanomedicine (Lond), vol 10(21): pp. 3287- 3304, 2015.
- D. Kalyane, N. Raval, R. Maheshwari, V. Tambe, K. Kalia, Rakesh K. Tekade. Employment of enhanced permeability and retention effect (EPR): Nanoparticle-based precision tools for targeting of therapeutic and diagnostic agent in cancer, Materials Science and Engineering: C, vol. 98: pp. 1252-1276, 2019.
- J. Oh, M. D. Feldman, J. Kim, C. Condit, S. Emelianov, T. E. Milner. Detection of magnetic nanoparticles in tissue using magneto-motive ultrasound. Nanotechnology, vol. 17: pp. 4183-4190, 2006.
- M.Fink, S. Lyer, C. Alexiou, H. Ermert. Sonographic detection of iron oxide nanoparticles employing shear waves. Current Directions in Biomedical Engineering, vol. 4(1), pp. 457-459, 2018.
- P. Hiltl, A. Grebner, M. Fink, S. J. Rupitsch, H. Ermert, G. Lee. Inertial cavitation of lyophilized and rehydrated nanopar- ticles of poly (L-lactic acid) at 835 kHz and 1.8 MPa ultra- sound. Scientific Reports, vol. 9(1): pp. 1-10, 2019.
- M .Wan, Y. Feng, G. t. Haar (Eds.). Cavitation in Biomedicine, Principles and Techniques, Springer, 2015.
- B. George, M. Lehner, M. Fink, S. J. Rupitsch, H. Ermert, P. T. Hiltl, U. Savšek, G. Lee. Determination of the Cavitation Pressure Threshold in Focused Ultrasound Wave Fields applied to Sonosensitive, Biocompatible Nanoparticles for Drug Delivery Applications, Current Directions in Biomedical Engineering, vol. 6(3): pp. 539-542, 2020.
Cited by
Sorted by citations
Thalmayer, A. S., Götz, K., Lübke, M., & Fischer, G. (2024) · Current Directions in Biomedical Engineering · doi:10.1515/cdbme-2024-2159
Metadata
- Authors
- Huber, C., George, B., Rupitsch, S. J., Ermert, H., Ullmann, I., Vossiek, M., & Lyer, S.
- Affiliations
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- University of Freiburg (DE)
- Universitätsklinikum Erlangen (DE)
- Corresponding author
- Huber, Christian
- ORCID
- Venue
- Current Directions in Biomedical Engineering
- Publisher
- Walter de Gruyter GmbH
- Published
- 2022-08-01
- Volume
- 8
- Issue
- 2
- Pages
- 568-571
- ISSN
- 2364-5504 (ISSN-L)
- OpenAlex
- W4294218656
- Cited by
- 9
- References
- 0
- Citations by year
- 2025: 6 · 2024: 3
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Current Directions in Biomedical Engineering (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft (452821018)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
- Physical Sciences › Physics and Astronomy › Acoustics and Ultrasonics › Ultrasound and Cavitation Phenomena
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- magnetic nanoparticles, acoustic cavitation, focused ultrasound, drug delivery, targeted drug release, magnetic guidance, tumor targeting, chemotherapeutics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review