The complex relationship between physical activity and diabetes: an overview
Abstract
Diabetes mellitus (DM) is a widespread condition, representing a challenging disease to manage. Exercise is being increasingly recommended as part of the therapeutic regimen for DM but the management of different forms of physical activity is difficult for individuals with diabetes, trainers, and physicians. Regular exercise can improve health and well-being, helping individuals to achieve their target lipid profile, body composition, cardio-respiratory fitness, and glycemic goals. People with diabetes tend to be as inactive as the general population, with a large percentage of individuals not achieving the minimum amount of recommended physical activity levels. Indeed, several barriers to exercise exist for persons with diabetes, including sports eligibility, multi-modality management of diabetic athletes, and inadequate knowledge about adequate type and intensity of exercise. The aim of the present review is to provide the current understanding of mechanisms, recommendations, and beneficial effects of different modalities of exercise for the treatment of DM.
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In subjects with diabetes or obesity, exercise increases insulin sensitivity independently of changes in body fat with nutritional interventions.
“In subjects with diabetes or obesity, exercise is the cornerstone of therapeutic interventions. It increases insulin sensitivity independently of changes in body fat with nutritional interventions”
From Effects of diet, lifestyle, Chrononutrition and alternative dietary interventions on postprandial Glycemia and insulin resistance (2022) · cites this paper as [241]
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References 91 · Cited by 35
- Authors
- Palermi, S., Iacono, O., Sirico, F., Modestino, M., Ruosi, C., Spera, R., & De Luca, M.
- Affiliations
- University of Naples Federico II (IT)
- Department of Translational Medical Sciences , University Federico II , Naples , Italy
- Venue
- Journal of Basic and Clinical Physiology and Pharmacology
- Publisher
- Walter de Gruyter GmbH
- Published
- 2021-09-29
- Volume
- 33
- Issue
- 5
- Pages
- 535-547
- ISSN
- 0792-6855 (ISSN-L)
- 2191-0286
- OpenAlex
- W3204529047
- Cited by
- 35
- References
- 91
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 9 · 2023: 6 · 2022: 11 · 2021: 1
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Basic and Clinical Physiology and Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- diabetes mellitus, physical activity, exercise therapy, barriers to exercise, sports eligibility, exercise intensity, glycemic control, lipid profile, body composition, cardiorespiratory fitness, exercise recommendations
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Diabetes Mellitus, Type 2, Humans, Lipids, Physical Fitness, Sports, Exercise
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