Decoy activity through microRNAs: the therapeutic implications
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miRNAs are highly conserved in mammalians.
“Importantly, miRNAs are highly conserved in mammalians17 and are crucial players in key cellular processes, such as inflammation, cell death, and differentiation.”
From TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity (2020) · cites this paper as [17]
Dysfunction in one single miRNA can concomitantly impair several biological functions by acting on distinct mRNA targets.
“Remarkably, dysfunction in one single miRNA can concomitantly impair several biological functions by acting on distinct mRNA targets, as previously described by us16–20.”
From TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity (2020) · cites this paper as [17]
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Research works printed but not linked: 31
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Sorted by citations
TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity
Brás, J. P., Bravo, J., Freitas, J., Barbosa, M. A., Santos, S. G., Summavielle, T., & Almeida, M. I. (2020) · Cell Death & Disease · doi:10.1038/s41419-020-2626-6 · Cited by 236 · see citing works
Self-citationManaging MicroRNAs with Vector-Encoded Decoy-Type Inhibitors
Bak, R. O., Hollensen, A. K., & Mikkelsen, J. G. (2013) · Molecular Therapy · doi:10.1038/mt.2013.113 · Cited by 49 · see citing works
- Authors
- Almeida, M. I., Reis, R. M., & Calin, G. A.
- Venue
- Expert Opinion on Biological Therapy
- Publisher
- Informa UK Limited
- Published
- 2012-06
- Volume
- 12
- Issue
- 9
- Pages
- 1153-1159
- ISSN
- 1471-2598
- 1744-7682
- PMC
- PMC3799811
- Cited by
- 30
- References
- 0
- Language
- en
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