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Cited by 793

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Cyclodextrins in drug delivery

Loftsson, Thorsteinn, Jarho, Pekka, Másson, Már, Järvinen, Tomi·2005·Expert Opinion on Drug Delivery

Abstract

Cyclodextrins are a family of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic central cavity. Cyclodextrin molecules are relatively large with a number of hydrogen donors and acceptors and, thus, in general they do not permeate lipophilic membranes. In the pharmaceutical industry cyclodextrins have mainly been used as complexing agents to increase aqueous solubility of poorly soluble drugs, and to increase their bioavailability and stability. Studies in both humans and animals have shown that cyclodextrins can be used to improve drug delivery from almost any type of drug formulation. However, the addition of cyclodextrins to existing formulations without further optimisation will seldom result in acceptable outcome. Currently there are approximately 30 different pharmaceutical products worldwide containing drug/cyclodextrin complexes on the market.

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Metadata

Authors
Loftsson, T., Jarho, P., Másson, M., & Järvinen, T.
Venue
Expert Opinion on Drug Delivery
Published
2005-03
Volume
2
Issue
2
Pages
335-351
ISSN
  • 1742-5247 (ISSN-L)
  • 1744-7593
OpenAlex
W2107001533
Cited by
793
References
3
FWCI
7.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cyclodextrins in drug delivery. https://app.cochat.ai/papers/10.1517/17425247.2.1.335
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Loftsson, T., Jarho, P., Másson, M., & Järvinen, T. (2005). Cyclodextrins in drug delivery. Expert Opinion on Drug Delivery. https://doi.org/10.1517/17425247.2.1.335

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.