EFFECT OF CREATINE PHOSPHATE SUPPLEMENTATION ON ANAEROBIC WORKING CAPACITY AND BODY WEIGHT AFTER TWO AND SIX DAYS OF LOADING IN MEN AND WOMEN
Abstract
The purpose of this study was to determine the effects of 2 and 6 days of creatine phosphate loading on anaerobic working capacity (AWC) and body weight (BW) in men and women. Sixty-one men (n = 31) and women (n = 30) randomly received 1 of 3 treatments (4 x 5 g.d(-1) x 6 days) using a double blind design: (a) 18 g dextrose as placebo (PL); (b) 5.0 g Cr + 20 g dextrose (Cr); or (c) 5.0 g Cr + 18 g dextrose + 4 g of sodium and potassium phosphates (CrP). AWC was determined at baseline and following 2 and 6 days of supplementation using the Critical Power Test. BW increased significantly over time, and the mean value for the men was significantly greater compared to that for women, but there were no interactions (p > 0.05). There were gender-specific responses for AWC expressed in both absolute values (kJ) and relative to BW (kJ. kg(-1)), with the women demonstrating no significant interactions. For the men, CrP loading significantly increased AWC following 2 days (23.8%) and 6 days (49.8%) of supplementation vs. PL (kJ and kJ.kg(-1)). Cr supplementation increased AWC 13-15% in both genders compared to PL (1.1%- 3.0% decline); although this result was not statistically significant, it may have some practical significance.
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Co-ingesting creatine monohydrate with HMB, beta-alanine, phosphates, or alpha-lipoic acid may have some additive effects.
“Several studies have also indicated that co-ingesting CM with other potentially ergogenic nutrients such as beta-hydroxy-beta-methylbutyrate (HMB) (Jowko et al. 2001), beta-alanine (Hoffman et al. 2006), phosphates (Eckerson et al. 2005), and alpha-lipoic acid (Burke et al. 2003b) may have some additive effects.”
From Analysis of the efficacy, safety, and regulatory status of novel forms of creatine (2011) · cites this paper as Eckerson et al. 2005
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Analysis of the efficacy, safety, and regulatory status of novel forms of creatine
Jäger, R., Purpura, M., Shao, A., Inoue, T., & Kreider, R. B. (2011) · Amino Acids · doi:10.1007/s00726-011-0874-6 · Cited by 181 · see citing works
Creatine supplementation in women's health: a lifespan perspective
Smith-Ryan, A. E., Cabre, H. E., Eckerson, J. M., & Candow, D. G. (2021) · Nutrients · doi:10.3390/nu13030877 · Cited by 92 · see citing works
Barber, J. J., McDermott, A. Y., McGaughey, K. J., Olmstead, J. D., & Hagobian, T. A. (2013) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e318252f6b7 · Cited by 40 · see citing works
Fazio, C., Elder, C. L., & Harris, M. M. (2022) · Journal of Strength & Conditioning Research · doi:10.1519/jsc.0000000000003873 · Cited by 20 · see citing works
- Authors
- Eckerson, J. M., Stout, J. R., Moore, G. A., Stone, N. J., Iwan, K. A., Gebauer, A. N., & Ginsberg, R.
- Affiliations
- Creighton University (US)
- Florida Atlantic University (US)
- Venue
- The Journal of Strength and Conditioning Research
- Published
- 2005
- Volume
- 19
- Issue
- 4
- Pages
- 756
- ISSN
- 1064-8011 (ISSN-L)
- 1533-4287
- OpenAlex
- W1964720379
- Cited by
- 50
- References
- 0
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 2 · 2016: 4 · 2015: 3 · 2014: 1 · 2013: 3 · 2012: 5
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Strength and Conditioning Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- creatine loading, body weight, sex differences, phosphate, dextrose placebo
- MeSH terms
- Adult, Analysis of Variance, Body Weight, Cardiotonic Agents, Double-Blind Method, Female, Humans, Male, Phosphocreatine, Sex Factors, Anaerobic Threshold, Ergometry, Dietary Supplements
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