The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mitochondrial DNA Sequence Analysis of Human Skeletal Remains: Identification of Remains from the Vietnam War
Abstract
Deoxyribonucleic acid (DNA) sequence analysis of the control region of the mitochondrial DNA (mtDNA) genome was used to identify human skeletal remains returned to the United States government by the Vietnamese government in 1984. The postmortem interval was thought to be 24 years at the time of testing, and the remains presumed to be an American service member. DNA typing methods using nuclear genomic DNA, HLA-DQ alpha [1] and the variable number of tandem repeat (VNTR) locus D1S80 [2], were unsuccessful using the polymerase chain reaction (PCR) [3]. Amplification of a portion of the mtDNA control region was performed, and the resulting PCR product subjected to DNA sequence analysis. The DNA sequence generated from the skeletal remains was identical to the maternal reference sequence, as well as the sequence generated from two siblings (sisters). The sequence was unique when compared to more than 650 DNA sequences found both in the literature and provided by personal communications. The individual sequence polymorphisms were present in only 23 of the more than 1300 nucleotide positions analyzed. These results support the observation [4] that in cases where conventional DNA typing is unavailable, mtDNA sequencing can be used for human remains identification.
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Cites
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Mitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature · doi:10.1038/325031a0 · Cited by 3,100
Maternal inheritance of human mitochondrial DNA.
Giles, R. E., Blanc, H., Cann, H. M., & Wallace, D. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.11.6715 · Cited by 1,365
Cited by
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Butler, J., Shen, Y., & McCord, B. (2003) · Journal of Forensic Sciences · doi:10.1520/jfs2003043 · Cited by 481
Prinz, M., Carracedo, A., Mayr, W. R., Morling, N., Parsons, T. J., Sajantila, A., Scheithauer, R., Schmitter, H., & Schneider, P. M. (2007) · Forensic Science International: Genetics · doi:10.1016/j.fsigen.2006.10.003 · Cited by 403
Validation of mitochondrial DNA sequencing for forensic casework analysis
Wilson, M. R., DiZinno, J. A., Polanskey, D., Replogle, J., & Budowle, B. (1995) · International Journal of Legal Medicine · doi:10.1007/bf01369907 · Cited by 351
Use of bleach to eliminate contaminating DNA from the surface of bones and teeth
Kemp, B. M., & Smith, D. G. (2005) · Forensic Science International · doi:10.1016/j.forsciint.2004.11.017 · Cited by 321
Quality of cell products: authenticity, identity, genomic stability and status of differentiation
Dittmar, K. E. J., Simann, M., Zghoul, N., Schön, O., Meyring, W., Hannig, H., Macke, L., Dirks, W. G., Miller, K., Garritsen, H. S. P., et al. (2010) · Transfusion Medicine and Hemotherapy · doi:10.1159/000284401 · Cited by 24
Metadata
- Authors
- Holland, M., Fisher, D., Mitchell, L., Rodriquez, W., Canik, J., Merril, C., & Weedn, V.
- Venue
- Journal of Forensic Sciences
- Publisher
- ASTM International
- Published
- 1993-05-01
- Volume
- 38
- Issue
- 3
- Pages
- 542-553
- ISSN
- 0022-1198 (ISSN-L)
- OpenAlex
- W1570931397
- Cited by
- 315
- References
- 3
- FWCI
- 4.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- Holland, M., Fisher, D., Mitchell, L., Rodriquez, W., Canik, J., Merril, C., & Weedn, V. (1993). Mitochondrial DNA Sequence Analysis of Human Skeletal Remains: Identification of Remains from the Vietnam War. Journal of Forensic Sciences. https://doi.org/10.1520/jfs13439j
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