A randomized controlled trial of cognitive behavior therapy for borderline personality disorder: rationale for trial, method, and description of sample
Open accessAbstract
This paper describes the rationale for a randomized controlled trial, comparing cognitive behavior therapy in addition to treatment as usual with treatment as usual alone, for borderline personality disorder. Previous pioneering randomized controlled trials of psychotherapies have suffered from methodological weaknesses and have not always been reported clearly to allow adequate evaluation of either the individual study or comparisons across studies to be undertaken. We report on the recruitment and randomization, design, and conduct of an ongoing randomized controlled trial of one hundred and six patients with borderline personality disorder. Primary and secondary hypotheses and their planned analyses are stated. The baseline characteristics of 106 patients meeting diagnostic criteria for borderline personality disorder are described.
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For Davidson 2006, attention bias was high risk because more attention was paid to experimental group participants.
“Attention bias: equal amounts of attention to all groups (obligatory treatment components)? High risk More attention paid to EG participants.”
From Psychological therapies for people with borderline personality disorder. (2012) · cites this paper as Davidson 2006
In CBT versus TAU (Davidson 2006), there were no statistically significant between-group differences at post-treatment for any outcome.
“There were no statistically significant between-group differences at post-treatment for any out outcome.”
From Psychological therapies for people with borderline personality disorder. (2012) · cites this paper as Davidson 2006
The Methods > Statistical Issues section (page unavailable) describes planned comparisons at 12 and 24 months, while Results > Recruitment reports how many patients were randomized. Neither reports post-treatment between-group results or whether differences were statistically significant (searched for post-treatment significance and 12-month CBT-versus-TAU outcomes). (LLM, conf=0.76)
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References 29 · Cited by 67
Research works printed but not linked: 29
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- Authors
- Davidson, K., Tyrer, P., Gumley, A., Tata, P., Norrie, J., Palmer, S., Millar, H., Drummond, L., Seivewright, H., Murray, H., & Macaulay, F.
- Affiliations
- University of Aberdeen (GB)
- Venue
- Journal of Personality Disorders
- Publisher
- Guilford Publications
- Published
- 2006-10
- Volume
- 20
- Issue
- 5
- Pages
- 431-449
- ISSN
- 0885-579X (ISSN-L)
- PMC
- PMC1847748
- OpenAlex
- W2006034893
- Cited by
- 67
- References
- 29
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 4 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 3 · 2013: 5 · 2012: 5
- FWCI
- 8.49
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Personality Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
- Funders
- Wellcome Trust (064027/Z01/Z, 064027)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- borderline personality disorder, cognitive behavioral therapy, usual care, psychotherapy efficacy, trial design, randomization, patient recruitment, baseline characteristics, hypothesis testing
- MeSH terms
- Adult, Aged, Borderline Personality Disorder, Female, Humans, Male, Middle Aged, Professional-Patient Relations, Psychiatric Status Rating Scales, Research Design, Cognitive Behavioral Therapy, Treatment Outcome, Patient Selection, Cross-Over Studies
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