Altered Phosphorylation of the Proteasome Subunit Rpt6 Has Minimal Impact on Synaptic Plasticity and Learning

Scudder, Samantha L.; Gonzales, Frankie R.; Howell, Kristin K.; Stein, Ivar S.; Dozier, Lara E.; Anagnostaras, Stephan G.; Zito, Karen; Patrick, Gentry N.

doi:10.1523/eneuro.0073-20.2021

Altered Phosphorylation of the Proteasome Subunit Rpt6 Has Minimal Impact on Synaptic Plasticity and Learning

Dynamic control of protein degradation via the ubiquitin proteasome system (UPS) is thought to play a crucial role in neuronal function and synaptic plasticity. The proteasome subunit Rpt6, an AAA ATPase subunit of the 19S regulatory particle (RP), has emerged as an important site for regulation …